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Abstract Transforming growth factor alpha (TGFα) is an important epidermal growth factor receptor (EGFR) ligand. Over-expression of both molecules in epithelial tumors has been correlated with poor prognosis and disease progression. Due... more
Abstract Transforming growth factor alpha (TGFα) is an important epidermal growth factor receptor (EGFR) ligand. Over-expression of both molecules in epithelial tumors has been correlated with poor prognosis and disease progression. Due to the importance of TGFα in ...
In this work several clones of a recombinant myeloma NS0 cell that were isolated in protein-free medium and selected by an integrated methodology that takes in account specific production and growth rates, stability of expression and... more
In this work several clones of a recombinant myeloma NS0 cell that were isolated in protein-free medium and selected by an integrated methodology that takes in account specific production and growth rates, stability of expression and resistance to apoptosis induced ...
In the present work we have carried out a comparative proteomic study of protein expression patterns by two-dimensional gel electrophoresis (2DE) in the pH range of 3–10 between the host cell line NS0 and cell lines that produce different... more
In the present work we have carried out a comparative proteomic study of protein expression patterns by two-dimensional gel electrophoresis (2DE) in the pH range of 3–10 between the host cell line NS0 and cell lines that produce different recombinant monoclonal antibodies ...