Browsing by Title

Now showing items 3390-3409 of 10098

    • G-proteins and adenylyl cyclase in Alzheimer's disease postmortem brain 

      Garcia-Jimnez, Angela (Institutionen för klinisk neurovetenskap, arbetsterapi och äldrevårdsforskning (NEUROTEC) / Department of Clinical Neuroscience, Occupational Therapy and Elderly Care Research (NEUROTEC), 2002-01-25)
      Alzheimer's disease (AD) is the most common type of dementia in the elderly. The major pathological changes seen in the disease are the formation of neurofibrillary tangles, of which the main component is the hyperphosphorylated ...

    • G1-phase cyclin expression in neoplastic B cells 

      Scuderi, Richard (Institutionen för medicin / Department of Medicine, 2002-08-16)
      By virtue of the role of G1-phase cyclin proteins as regulators of differentiation, proliferation, and apoptosis, their improper expression can lead to altered cellular homeostasis and tumor formation. Cyclins provide the ...

    • GABA and human spermatozoa : characterization and regulation of GABA transport proteins 

      Aanesen, Arthur (Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 1998-09-04)
      The present project aimed at investigating the interaction between GABA and human spermatozoa under in vitro conditions. Our initial hypothesis was that human spermatozoa had specific binding proteins for GABA and that the ...

    • Gait and balance in Parkinson's disease : psychometric properties and effects of training 

      Löfgren, Niklas (Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2016-05-11)
      Aim: The overarching aims of this thesis were to: evaluate the psychometric properties of a new clinical balance tool in People with Parkinson’s disease (PwPD) with mild to moderate disease severity; as well as to investigate ...

    • Gait in patients with knee osteoarthritis : effects of preoperative physical therapy and two surgical interventions 

      Börjesson, Margareta (Institutionen för klinisk neurovetenskap, arbetsterapi och äldrevårdsforskning (NEUROTEC) / Department of Clinical Neuroscience, Occupational Therapy and Elderly Care Research (NEUROTEC), 2004-09-16)
      Introduction: Knee osteoarthritis is a common joint disease with impact on all different aspects of health. This thesis will focus on time and distance measurements of gait and clinical tests in patients with ...

    • Gait strategy in myelomeningocele : movements, mechanics and methods 

      Gutierrez, Elena M (Institutionen för kirurgisk vetenskap / Department of Surgical Science, 2003-09-26)
      The overall aim of this thesis was to describe the movement patterns employed in self-ambulatory children with a range of muscle paresis due to nervous tissue damage resulting from myelomeningocele, a common congenital ...

    • Galanin : a modulator of serotonin neurotransmission : relevance for depression 

      Razani, Haleh (Institutionen för neurovetenskap / Department of Neuroscience, 2001-03-02)
      Galanin is widely distributed throughout the central nervous system with multiple and diverse biological roles. In the rat, galanin-like immunoreactivity is expressed in a population of5-hydroxytryptamine (5-HT, serotonin) ...

    • Galanin and Leu-enkephalin in the rat : with special reference to adjuvant arthritis 

      Wu, Qinyang (Institutionen för laboratoriemedicin / Department of Laboratory Medicine, 2004-05-20)
      In these studies, the tissue and cellular distribution of Galanin and Leu-enkephalin were demonstrated in normal bone and joints. Furthermore, tissue levels of Galanin and Leuenkephalin were also studied in the ankles ...

    • Galanin in the pituitary and in human circulation : clinical and experimental studies 

      Grenbäck, Eva (Institutionen för molekylär medicin och kirurgi / Department of Molecular Medicine and Surgery, 2006-11-24)
      The neuropeptide galanin has important roles in the central and peripheral nervous systems where it affects memory, seizure activity, appetite and pain transmission. Galanin is also present in the endocrine system and one ...

    • Galanin receptor subtypes in rodent models of mood disorders 

      Wardi-Le Maitre, Tara (Institutionen för neurovetenskap / Department of Neuroscience, 2010-03-05)
      Major depressive disorder (MDD) is a serious mental illness, with a complex etiology. It is a multifactorial disorder caused by a combination of genetic, environmental and epigenetic factors. Exposure to stressful life ...

    • Gallbladder and pancreatic disease in patients with primary sclerosing cholangitis 

      Said, Karouk (Institutionen för medicin, Huddinge Sjukhus / Department of Medicine at Huddinge University Hospital, 2010-05-21)
      The aims of this study were to assess the occurrence of gallbladder abnormalities and dysfunction, to evaluate clinically useful biomarkers for premalignancy and malignancy in gallbladder epithelium and to assess presence ...

    • Gallstone disease in a Swedish population : an epidemiological investigation 

      Muhrbeck, Olle (Inst för kliniska vetenskaper, Danderyds sjukhus / Dept of Clinical Sciences, Danderyd Hospital, 1995-11-24)
      The main objective of the present thesis was to study the prevalence of gallstone disease in a community survey in Danderyd. Symptoms and risk factors for gallstone disease and the changing incidence of cholecystectomy in ...

    • Gamma knife surgery of cerebral arteriovenous malformations 

      Karlsson, Bengt (Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 1996-05-23)
      Aims of the study: to define and quantify parameters of importance for the treatment result in Gamma Knife (GK) surgery of arteriovenous malformations (AVM). To determine the natural course of AVM in order to calculate the ...

    • Gastrectomy compared to oesophagectomy for Siewert II and III gastro-oesophageal junctional cancer in relation to resection margins, lymphadenectomy and survival 

      Kauppila, Joonas H; Wahlin, Karl; Lagergren, Jesper (Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2018-02-12)
      It is unclear whether gastrectomy or oesophagectomy offer better outcomes for gastro-oesophageal junction (GOJ) cancer. A total of 240 patients undergoing total gastrectomy (n = 85) or oesophagectomy (n = 155) for Siewert ...

    • Gastric acid secretion and gut peptides : mechanisms involved in inflammatory response 

      Feldreich, Tobias Rudholm (Institutionen för medicin / Department of Medicine, 2010-10-08)
      The regulation of gastric acid secretion is complex and involves endocrine, paracrine, and neurocrine mechanisms. Among these, the interconnecting cross-talk between different gut peptides is an important part in the control ...

    • Gastric bypass : positive and negative health effects 

      Backman, Olof (Inst för kliniska vetenskaper, Danderyds sjukhus / Dept of Clinical Sciences, Danderyd Hospital, 2017-12-15)
      Obesity is a major health problem worldwide. It is preventable in theory, but in practice no country has been able to stop the development of increasing obesity. The only available treatment with sufficient long-term effect ...

    • Gastroesephageal reflux and related motility disorders after esophageal atresia : a clinical study 

      Montgomery, Madeleine (Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 1997-04-04)
      The most common congenital malformation of the esophagus is esophageal atresia (EA) with or without tracheoesophageal fistula (TEF). Successful repair of EA does not ensure normal esophageal function. Disturbed esophageal ...

    • Gastroesophageal reflux : etiological factors 

      Nordenstedt, Helena (Institutionen för molekylär medicin och kirurgi / Department of Molecular Medicine and Surgery, 2007-05-18)
      Gastroesophageal reflux disease (GERD) is one of the most common health problems in the Western world today, affecting up to 20% of the adult population weekly and 50% monthly, generating substantial suffering among patients ...

    • Gastroesophageal reflux and sleep problems 

      Lindam, Anna (Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2014-08-15)
      Gastroesophageal reflux disease (GERD) and sleep problems are common health problems in the Western world affecting up to 30% and 33% of the population respectively. GERD is associated with decreased quality of life, ...

    • Gastroesophageal reflux disease in adults : the Kalixanda study : a population-based endoscopic study 

      Ronkainen, Jukka (Institutionen för neurobiologi, vårdvetenskap och samhälle / Department of Neurobiology, Care Sciences and Society, 2006-12-21)
      Gastroesophageal reflux disease (GERD) is a common burden on health care resources in the Western world and deteriorates the health-related quality of life of those affected, but its manifestations in the general population ...