Browsing by Title

Now showing items 10086-10100 of 10100

    • X-chromosome upregulation is driven by increased burst frequency 

      Larsson , Anton J M; Coucoravas, Christos; Sandberg, Rickard; Reinius, Björn (Inst för medicinsk biokemi och biofysik / Dept of Medical Biochemistry and BiophysicsInst för cell- och molekylärbiologi / Dept of Cell and Molecular Biology, 2020-05-12)
      Ohno's hypothesis postulates that X-chromosome upregulation rectifies X-dose imbalance relative to autosomal genes, present in two active copies per cell. Here we dissected X-upregulation into kinetics of transcription, ...

    • X-ray structure analysis of short-chain dehydrogenases/reductases 

      Benach-Andreu, Jordi (Biovetenskaper och näringslära / Biosciences and Nutrition, 1999-04-26)
      X-ray crystallography and site-directed mutagenesis were used to better understand the structure/function relationships in the family of short-chain dehydrogenases/reductases (SDR). This group of enzymes constitutes a ...

    • Xenobiotics-induced phosphorylations of MDM2 

      Pääjärvi, Gerd (Institutet för miljömedicin (IMM) / Institute of Enviromental Medicine, 2006-11-24)
      The aim of the present study was to characterize the Mdm2 and p53 responses induced by DNA damaging xenobiotics and how these responses can be modified by non-genotoxic xenobiotics. During control conditions cellular levels ...

    • Yoga vid långvarig smärta. En systematisk litteraturstudie 

      Tell, Camilla (Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2013-08-28)
      Background: Patients with chronic pain are treated with various forms of treatment in primary care. Chronic pain is a major health problem and a disease in itself. It affects many factors in life, both physical and mental. ...

    • Yogaträning för barn med cerebral pares : ledrörlighet och muskelelasticitet i nedre extremiteterna 

      Isakson, Erika (Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2015-06-16)
      Background: Movement and posture are always affected in children with cerebral palsy (CP). Motor symptoms vary in degree and severity, however a decreased joint mobility in the lower extremities is common. With increasing ...

    • You are how you eat : decelerated eating may protect from obesity and eating disorders 

      Zandian, Modjtaba (Institutionen för neurobiologi, vårdvetenskap och samhälle / Department of Neurobiology, Care Sciences and Society, 2009-05-14)
      On a new framework for anorexia nervosa, learning to eat is central intervention; as patients regain a normal pattern of eating their problems dissolve. Mandometer®, a development of previous methods, allows simultaneous ...

    • Young adults in urban Pakistan : barriers and challenges for improving health behaviors in the wake of the HIV/AIDS epidemic 

      Hasnain, Syed Farid-ul (Institutionen för folkhälsovetenskap / Department of Public Health Sciences, 2010-08-26)
      Background: HIV/AIDS is spreading globally more specifically among the younger generation. The impact of HIV/AIDS on the youth cannot be underestimated. According to the UNAIDS report 2008; an estimated number of 33 ...

    • Young men's sexuality and sexually transmitted infections in Zambia 

      Ndubani, Phillimon (Institutionen för folkhälsovetenskap / Department of Public Health Sciences, 2002-10-04)
      Aim: To describe and analyse young Zambian men's sexuality and implications for sexually transmitted infections (STIs) including HIV/AIDS in Chiawa rural community and Lusaka urban compound of Misisi. Methods: Over ...

    • Young sex offenders : individual characteristics, agency reactions and criminal recidivism 

      Långström, Niklas (Institutionen för folkhälsovetenskap / Department of Public Health Sciences, 1999-04-21)
      Background: Young sex offenders (YSOs) commit a significant proportion of all reported sex crimes and many adult sex offenders report deviant sexual fantasies and sexually abusive behaviour already during adolescence. ...

    • Yrsel ur patientens perspektiv : en klinisk och epidemiologisk studie på personer med öronrelaterad yrsel 

      Mendel, Barbro (Institutionen för neurobiologi, vårdvetenskap och samhälle / Department of Neurobiology, Care Sciences and Society, 2007-11-09)
      The overall aim of this thesis was to characterize and improve assessment of self-rated health and quality of life in patients with peripheral vestibular disorder, with the ultimate goal of developing the care ...

    • Zebrafish as a model to study the neuroendocrine system and toxicity of endocrine disruptors 

      Chandrasekar, Gayathri (Inst för biovetenskaper och näringslära / Dept of Biosciences and Nutrition, 2010-12-17)
      Zebrafish is a popular vertebrate model system to study development and perform genetic analysis. It offers numerous advantages such as small size, short generation time, high fecundity, rapid and ex utero development of ...

    • β-alanine synthase : one reaction, two folds and mechanisms 

      Lundgren, Stina (Institutionen för medicinsk biokemi och biofysik (MBB) / Department of Medical Biochemistry and Biophysics, 2008-01-11)
      beta-alanine synthase (betaAS) is the third enzyme in the reductive pyrimidine catabolic pathway which is responsible for the breakdown of pyrimidine bases, including several anti-cancer drugs in higher organisms. We ...

    • ‛The virus stops with me’ : couples living positively with HIV in rural, eastern Uganda 

      King, Rachel Lisa (Inst för folkhälsovetenskap / Dept of Public Health Sciences, 2012-09-21)
      Background: Historically people living with HIV (PLHIV) were left out of the center of the HIV prevention agenda in Africa, yet more recently greater attention has been placed on interventions that forefront PLHIV. Aim: ...

    • “Should i stay, or should i go” : teachers’ motivation to stay at their workplace 

      Casely-Hayford, Jeffrey (Institutet för miljömedicin / Institute of Environmental Medicine, 2024-05-20)
      The overarching aim of this thesis was to increase the knowledge on the relationship between teachers’ psychosocial work environment and teachers’ retention intention. This was done by exploring the psychosocial work factors ...

    • ”I'm afraid, you'll have to help yourself” : people with emotionally unstable personality disorder view on meeting in healthcare 

      Hallén, Johanna; Pettersson, Katarina (Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2016-09-12)
      Background: Mental illness is one of our major public health problem and has for a long time increased both internationally and in Sweden (Socialstyrelsen, 2015). A need for knowledge of how to treat these patients adequately ...