The advances in knowledge about production and stability of dispersed systems enable the development of differentiated vehicles such as nanoemulsions and nanoemulgels, which have been effectively used to increase the bioavailability and... more
The advances in knowledge about production and stability of dispersed systems enable the development of differentiated vehicles such as nanoemulsions and nanoemulgels, which have been effectively used to increase the bioavailability and improve the stability of the active ingredients. Nowadays there is an intensely usage of natural bioactive materials as medicinal agent in pharmaceutical industries. Swietenia macrophylla oil is used due to the bioactivity of different parts of the plant as anti-inflammatory, anti-mutagenicity, anti-tumor. SM oil Nanoemulgels were prepared by incorporating nanoemulsion with hydrogel. First by preparing mixtures of oil, glycerol with sucrose ester (Laurate, Oleate and Palmitate) to produce pre-nanoemulsion using phase inversion technique, then nanoemulsion was produced using self-emulsification technique. After that, hydrogel was added to nanoemulsion to produce nanoemulgel. It was found that 50% oil with sucrose laurate 20% and 30% glycerol was able ...