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We measured apolipoproteins (apo) A-I and B by rate immunonephelometry (rate INA) during Phase 1 of the National Health and Nutrition Examination Survey (NHANES) III. We also made the measurements by radial immunodiffusion (RID) in a 20%... more
Orotic acid (ORA) is an important biochemical marker for uridine monophosphate synthase deficiency, an autoso-mal recessive disease characterized by macrocytic hypo-chromic megaloblastic anemia, growth retardation, orotic aciduria, and... more
Me medicine vs. we medicine: reclaiming biotechnology for the common good, by Donna Dickenson, New York, Columbia University Press, 2013, 296 pp., £19.95 (hardback), ISBN 978-0-231-15974-6 “Is personalised medicine replacing public... more
BACKGROUND High-sensitivity cardiac troponin T (hs-cTnT) is a biomarker used in diagnosing myocardial injury. The clinical utility and the variation of this biomarker over time remain unclear in hemodialysis (HD) and peritoneal dialysis... more
The first generation of troponin T ELISA (TnT 1) can yield false-positive results in patients with severe skeletal muscle injury. Therefore, a cardiac-specific second-generation troponin T ELISA (TnT 2) was developed, in which the... more
Background: Circulating osteocalcin is a well-known marker for bone formation, but none of the commercial kits currently available can be used in automated sys- tems. Here we present the first semiautomated assay for human serum... more
We aimed to evaluate the in vitro osteogenic and osteoinductive potentials of BioS-2P and its ability to promote in vivo bone repair. To investigate osteogenic potential, UMR-106 osteoblastic cells were cultured on BioS-2P and Bioglass... more
We studied the changes in blood glucose concentration in blood samples collected in heparinized specimen tubes containing no other preservative, or containing NaF, D-mannose, or a combination of NaF and D-mannose. Blood concentration in... more
Cancer biomarkers are commonly used in pediatrics to monitor cancer progression, recurrence, and prognosis, but pediatric reference value distributions have not been well established for these markers. The Canadian Laboratory Initiative... more
The ABCA1 gene encodes for a member of subfamily A of the ATP-binding cassette transporters that plays an important role in cellular export of cholesterol and phospholipids; therefore, quantification of the ABCA1 mRNA is critical in many... more