Plant molecular farming: systems and products

ME Horn, SL Woodard, JA Howard - Plant cell reports, 2004 - Springer
Plant molecular farming is a new and promising industry involving plant biotechnology. In
this review, we describe several diverse plant systems that have been developed to produce …

Monoclonal antibody manufacturing in transgenic plants—myths and realities

EE Hood, SL Woodard, ME Horn - Current opinion in biotechnology, 2002 - Elsevier
The number and types of antibodies expressed in plants has increased steadily since the
first reports of this accomplishment in the 1980s, illustrating the versatility of plants as a …

Plant-based vaccines: unique advantages

…, DD Turner, MR Bailey, JM Mayor, SL Woodard… - Vaccine, 2001 - Elsevier
Numerous studies have shown that viral epitopes and subunits of bacterial toxins can be
expressed and correctly processed in transgenic plants. The recombinant proteins induce …

Maize (Zea mays)‐derived bovine trypsin: characterization of the first large‐scale, commercial protein product from transgenic plants

SL Woodard, JM Mayor, MR Bailey… - Biotechnology and …, 2003 - Wiley Online Library
Bovine trypsin (EC 3.4. 21.4) is an enzyme that is widely used for commercial purposes to
digest or process other proteins, including some therapeutic proteins. The …

Delivery of subunit vaccines in maize seed

…, DE Delaney, M Garcia, B Wiggins, SL Woodard… - Journal of Controlled …, 2002 - Elsevier
The use of recombinant gene technologies by the vaccine industry has revolutionized the
way antigens are generated, and has provided safer, more effective means of protecting …

Downstream processing of recombinant proteins from transgenic feedstock

ZL Nikolov, SL Woodard - Current opinion in biotechnology, 2004 - Elsevier
The search for inexpensive production systems capable of producing large quantities of
recombinant protein has resulted in the development of new technology platforms based on …

Expression of the sweet protein brazzein in maize for production of a new commercial sweetener

…, SJ Streatfield, Z Nikolov, SL Woodard… - Plant biotechnology …, 2005 - Wiley Online Library
The availability of foods low in sugar content yet high in flavour is critically important to
millions of individuals conscious of carbohydrate intake for diabetic or dietetic purposes …

Improved recovery of active recombinant laccase from maize seed

MR Bailey, SL Woodard, E Callaway, K Beifuss… - Applied Microbiology …, 2004 - Springer
Lignolytic enzymes such as laccase have been difficult to over-express in an active form.
This paper describes the expression, characterization, and application of a fungal laccase in …

Development of an edible subunit vaccine in corn against enterotoxigenic strains of Escherichia coli

…, C Brooks, BJ Lamphear, SL Woodard… - In Vitro Cellular & …, 2002 - Springer
Advances in the development of subunit vaccines and in the production of foreign proteins in
plants together offer the prospect of stable and inexpensive vaccine delivery systems …

Fluorescent derivatives of diphenyl [1-(N-peptidylamino) alkyl] phosphonate esters: synthesis and use in the inhibition and cellular localization of serine proteases

AS Abuelyaman, D Hudig, SL Woodard… - Bioconjugate …, 1994 - ACS Publications
9500 M_1 s_1) and 600-fold better than it did PPE (A0bad/[I]= 16 M_1 s-1). FTC-Aca-Ala-Ala-
Metp (OPh) 2 (1) was a more effective inhibitor of chymotrypsin (fc0bsd/[I]= 190 M_1 s_1) …