Numerous studies have shown that viral epitopes and subunits of bacterial toxins can be
expressed and correctly processed in transgenic plants. The recombinant proteins induce …

The use of recombinant gene technologies by the vaccine industry has revolutionized the
way antigens are generated, and has provided safer, more effective means of protecting …

Advances in the development of subunit vaccines and in the production of foreign proteins in
plants together offer the prospect of stable and inexpensive vaccine delivery systems …

Transgenic plant-derived vaccines comprise a new type of bioreactor that combines plant
genetic engineering technology with an organism's immunological response. This …

The synthesis of selected antigens in plants and their oral delivery has great potential for
reducing the costs of vaccine production and administration. The application of this …

Transgenic plants expressing recombinant proteins from pathogenic microorganisms
provide an inexpensive edible vaccine for induction of local immunity. Three transgenic …

The use of edible plants for the production and delivery of vaccine proteins could provide an
economical alternative to fermentation systems. Genes encoding bacterial and viral antigens …

Epitopes often require co-delivery with an adjuvant or targeting protein to enable recognition
by the immune system. This paper reports the ability of transgenic tomato plants to express a …

Plants have been identified as promising expression systems for commercial production of
vaccine antigens. In phase I clinical trials several plant-derived vaccine antigens have been …

The authors have designed and constructed a plant-optimized synthetic gene encoding the
Escherichia coli heat-labile enterotoxin B subunit (LT-B), for use in transgenic plants as an …