Precision Medicine in Breast Cancer: A Molecular Genomics and Diagnostics Approach

H Dalal - 2024 - portal.research.lu.se
… HER2/ERBB2 DNA copy number quantification and HER2-low … strategies using large scale
analyses of breast cancer … as a potential predictive biomarker to identify which patients will …

A Survey on Evolutionary Computation for Identifying Biomarkers of Complex Disease

J Liang, Z Hu, Y Bi, H Cheng, K Yu… - … Computation, 2024 - ieeexplore.ieee.org
… (eg, cancer). With the advancement of high-throughput sequencing technology, there has …
zero; the latter is employed to selectively remove isolated genes, and it can get multi-modal …

NNICE: a deep quantile neural network algorithm for expression deconvolution

YW Jin, P Hu, Q Liu - Scientific Reports, 2024 - nature.com
… Take the immune cell types as examples, in most cancers, higher … can be identified from
bulk transcriptomic data by computational … scRNA-seq datasets from immune cells isolated by …

The Advancement and Application of the Single-Cell Transcriptome in Biological and Medical Research

K Huang, Y Xu, T Feng, H Lan, F Ling, H Xiang, Q Liu - Biology, 2024 - mdpi.com
… since its inception in 2009. Unlike bulk RNA-seq, scRNA-seq … in scRNA-seq for the
isolation of individual cells include … -chromatin with high-throughput sequencing (scATAC-seq), …

De novo assembly of transcriptomes and differential gene expression analysis using short-read data from emerging model organisms–a brief guide

DJ Jackson, N Cerveau, N Posnien - Frontiers in Zoology, 2024 - Springer
High-throughput sequencing methods have been a triumph in … identification and molecular
isolation of specific gene … assembly artefacts and significantly increase computing time [52]. If …

Review on the evolution in DNA-based techniques for molecular characterization and authentication of GMOs

Z Liang, L Ding, M Tang, X Wang, X Chen, J Xu… - Microchemical …, 2024 - Elsevier
… Its high-throughput sequencing technology has effectively addressed the limitations of
traditional identification … was successfully used to isolate flanking sequences from the transgenic …

Revolutionizing Synthetic Antibody Design: Harnessing Artificial Intelligence and Deep Sequencing Big Data for Unprecedented Advances

E Gallo - Molecular Biotechnology, 2024 - Springer
… and cost-effective high-throughput sequencing of DNA and … high-throughput computational
analyses of the enriched … S1 and S2 subunits to enrich and isolate spike protein-specific Abs …

Transcriptome analysis: a powerful tool to understand individual microbial behaviors and interactions in ecosystems

Y Sato - Bioscience, Biotechnology, and Biochemistry, 2024 - academic.oup.com
… With the development of high-throughput sequencing technology, … we can identify the
metabolic reactions promoted by the … A review of computational tools for generating metagenome-…

Cell Population Identification and Benchmarking of Tools in Single-Cell Data Analysis

A Sonrel - 2024 - zora.uzh.ch
High-throughput sequencing technologies are now widely … development of a new
computational platform, Omnibenchmark… each isolated cell transcripts to retrieve downstream the …

Regulation of tumor metastasis and CD8+ T cells infiltration by circRNF216/miR-576-5p/ZC3H12C axis in colorectal cancer

W Du, X Quan, C Wang, Q Song, J Mou… - Cellular & Molecular …, 2024 - Springer
… cells (PBMCs) were isolated from healthy individuals using density gradient … identified in
eukaryotes thanks to the advances in high-throughput sequencing and unbiased computational