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Edexcel International GCSE (9-1) Biology Student Book sample chapter

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Student Book EDEXCEL INTERNATIONAL GCSE (9-1) BIOLOGY • Develop your practical skills with investigative tasks • Check your progress and understanding using the end of the topic checklists and in-text questions • Practise your exam technique with exam-style questions in each section, annotated examples and further guidance • Gain insights into the real-life uses of science through the Science in Context sections

Biology Teacher Pack ISBN: 9780008236229

Chemistry Student Book ISBN: 9780008236212

Physics Student Book ISBN: 9780008236205

Chemistry Teacher Pack ISBN: 9780008236243

Physics Teacher Pack ISBN: 9780008236236

EDEXCEL INTERNATIONAL GCSE (9-1) BIOLOGY

Collins Edexcel International GCSE Biology provides all the material you need for your International GCSE 9-1 qualification.

EDEXCEL INTERNATIONAL GCSE (9-1) BIOLOGY Jackie Clegg, Sue Kearsey, Gareth Price and Mike Smith

ISBN 978-0-00-823619-9

9 780008 236199

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Contents

Section 2 Structure and functions in living organisms..................28

The International GCSE examination....374 Overview.......................................................................374 Assessment objectives and weightings.............375 Examination tips.........................................................375 Answering questions................................................378

Developing experimental skills..............380

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a) Level of organisation............................................30 b) Cell structure..........................................................36 c) Biological molecules.............................................43 d) Movement of substances into and out of cells...............................................................55 e) Nutrition...................................................................68 f) Respiration...............................................................97 g) Gas exchange.........................................................105 h) Transport..................................................................124 i) Excretion....................................................................148 j) Coordination and response................................157 k) Exam-style questions...........................................177

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a) Characteristics of living organisms.................10 b) Variety of living organisms................................15 c) Exam-style questions...........................................25

a) Food production....................................................322 b) Selective breeding................................................342 c) Genetic modification (genetic engineering)..........................................350 d) Cloning.....................................................................359 e) Exam-style questions...........................................367

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Section 1 The nature and variety of living organisms......................8

Section 5 Use of biological resources......................320

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Getting the best from the book............................4

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Planning and assessing the risk............................380 Carrying out the practical work safely and skilfully......................................................386 Making and recording observations and measurements....................................................390 Analysing the data and drawing conclusions...................................................................393 Evaluating the data and methods used.............400

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Section 3 Reproduction and inheritance.............188

a) Reproduction..........................................................190 b) Inheritance..............................................................214 c) Exam-style questions...........................................248

Mathematical skills....................................404 Glossary.........................................................................406 Answers..........................................................................415 Index...............................................................................434

Section 4 Ecology and the environment................254

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a) The organism in the environment..................256 b) Feeding relationships..........................................268 c) Cycles within ecosystems...................................283 d) Human influences on the environment........293 e) Exam-style questions...........................................311

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Getting the best from the book Welcome to Edexcel International GCSE Biology.

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This textbook has been designed to help you understand all of the requirements needed to succeed in the Edexcel International GCSE Biology course. Just as there are five sections in the Edexcel specification, so there are five sections in the textbook: The nature and variety of living organisms, Structure and functions in living organisms, Reproduction and inheritance, Ecology and the environment and Use of biological resources.

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Each section is split into topics. Each topic in the textbook covers the essential knowledge and skills you need. The textbook also has some very useful features which have been designed to really help you understand all the aspects of Biology which you will need to know for this specification.

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SAFETY IN THE SCIENCE LESSON This book is a textbook, not a laboratory or practical manual. As such, you should not interpret any information in this book related to practical work as including comprehensive safety instructions. Your teachers will provide full guidance for practical work and cover rules that are specific to your school.

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A brief introduction to the section to give context to the science covered in the section.

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Before the development of farming around 10 000 years ago, humans were hunter-gatherers, taking food from the wide range of plants and animals that lived in their community. As they developed the skills of farming, humans had to choose plants and animals that grew well in the local environment and provided the most food for the rapidly growing human population.

Use of biological resources

Today we rely on a small number of plant and animal species to provide all our food. Over thousands of years, these species have been changed as they have become domesticated. Selective breeding has developed breeds and varieties that produce more of what we need, such as sheep that produce more wool, animals that have much larger muscles for the meat we eat, grain crops like wheat that produce much larger seeds. As the human population continues to grow, we need even more food. Many people hope that the new techniques of genetic engineering and cloning will help improve crop plants and farm animals so that we can continue to produce enough food for everyone.

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Starting points will help you to revise previous learning and see what you already know about the ideas to be covered in the section.

STARTING POINTS 1. Plants grow best under certain conditions. What are the best conditions for plant growth and how can we manipulate the environment to create them? 2. Pests reduce the yield of crops. What methods can be used to control crop pests and what are the advantages and disadvantages of each method? 3. We use microorganisms to make many foods. What conditions do microorganisms need for growth, and what foods can we produce using them? 4. We are increasingly farming fish in order to provide the food we need. What conditions do fish farms need to provide to maximise the growth of the fish? 5. Most of our animal breeds and crop plant varieties have been developed through selective breeding. How is this done? 6. Genetic modification is a technique that we hear about frequently in the media. What is it and what are its advantages and problems? 7. Cloning is another technique that is being used to develop plants and animals with the characteristics we need. How is cloning done, and what could it be used for?

SECTION CONTENTS a) Food production b) Selective breeding c) Genetic modification (genetic engineering) d) Cloning e) Exam-style questions ∆ The wheat in this field has been bred selectively to produce a better yield.

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The section contents shows the separate topics to be studied matching the specification order.

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Excretion

of photosynthesis. Excess amounts of these gases (not needed for other processes) are excreted through the stomata of the leaves.

INTRODUCTION

The shedding of leaves by trees, either all together in the autumn by deciduous trees or a few at a time by evergreens, is a form of excretion. Trees store metabolic waste substances in cells in the leaves, out of the way so that they do not interfere with other life processes. When the leaves are shed, this waste is shed also – we say it has been excreted because it has been removed from the body of the tree.

Knowledge check shows the ideas you should have already encountered in previous work before starting the topic.

EXCRETION IN HUMANS The metabolic activities in human cells produce many waste products that need to be excreted. Carbon dioxide is the waste product from respiration. If it remained in cells, it would change their pH and affect the activity of enzymes. It diffuses from respiring cells into the plasma of the blood and is carried around the body until it ∆ Fig. 2.104 Sweat is water and ions that have reaches the lungs. There it diffuses through the been secreted from the body via the skin. capillary and alveoli walls and is breathed out. The skin plays a minor part in excretion. Sweat, which is secreted on to the skin surface from special cells in the skin, contains water and some minerals such as sodium and chloride ions (salt). Waste products of many cell processes dissolve in the blood and are carried to the kidneys, where they are excreted. These products include Section through urea, produced from the breakdown of excess amino acids by the liver. human kidney

∆ Fig. 2.103 Shedding leaves is a way of getting rid of waste.

KNOWLEDGE CHECK ✓ Plants produce oxygen from photosynthesis, and plants and animals release carbon dioxide from respiration – these are waste substances if they are not used in other processes. ✓ Excess amino acids from digestion are broken down to form urea in the liver.

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branch of the renal artery glomerulus

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Learning objectives cover what you need to learn in this topic.

THE URINARY SYSTEM Humans have two kidneys situated just under the rib kidney cage at the back of the body, about halfway down the renal artery renal spine. The kidneys are well supplied with blood, which renal vein artery enters through the renal arteries and leaves through the renal veins. Inside the kidneys, the blood is filtered to renal ureter remove waste substances no longer needed by the vein ring of muscle bladder body. These include excess water, urea and mineral ureter urethra ions, which together form urine. Urine flows out of the kidneys down the ureters and into the bladder. The urine is stored in the bladder until a ring of muscle ∆ Fig. 2.105 The human urinary system. at the base is relaxed (usually when you go to the toilet). The urine then flows out of the bladder, through the urethra to the environment.

Bowman’s capsule proximal convoluted tubule

lo H medulla

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QUESTIONS

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LEARNING OBJECTIVES ✓ In plants, understand the origin of carbon dioxide and oxygen as waste products of metabolism and their loss from the stomata of a leaf. ✓ In humans, know the excretory products of the lungs, kidneys and skin (organs of excretion). ✓ Understand how the kidney carries out its roles of excretion and osmoregulation. ✓ Describe the structure of the urinary system, including the kidneys, ureters, bladder and urethra. ✓ Describe the structure of a nephron, to include Bowman’s capsule and glomerulus, convoluted tubules, loop of Henle and collecting duct. ✓ Describe ultrafiltration in the Bowman’s capsule and the composition of the glomerular filtrate. ✓ Understand how water is reabsorbed into the blood from the collecting duct. ✓ Understand why selective reabsorption of glucose occurs at the proximal convoluted tubule. ✓ Describe the role of ADH in regulating the water content of the blood. ✓ Understand that urine contains water, urea and ions.

A kidney tubule branch of the renal vein pelvis

1. Which is the main organ of excretion in plants? Explain your choice.

2. Which are the main organs of excretion in humans? Explain your choices.

3. Draw up a table to list the main structures of the urinary system

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The blue side panels and background shading indicate content for Biology International GCSE students only.

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Examples of investigations are included with questions matched to the investigative skills you will need to learn.

Questions to check your understanding.

QUESTIONS

Developing investigative skills

1. List three factors that affect the rate of photosynthesis.

You can investigate the effect of light on photosynthesis by shining a light on a water plant and measuring how quickly bubbles are given off, as shown in Fig. 2.45.

2. Explain how each of these factors affects the rate of

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and their functions.

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EXCRETION IN FLOWERING PLANTS Excretion is defined as the process or processes by which an organism eliminates the waste products of its metabolic activities. (Remember that excretion is different from egestion.) In flowering plants two waste products that need to be excreted are carbon dioxide and oxygen. Carbon dioxide is produced in respiration while oxygen is a product

photosynthesis.

3. Explain as fully as possible why a variegated leaf tested for starch only causes the iodine/potassium iodide solution to turn from brown to blue-black where the leaf was green.

bubble of gas

filament light bulb (Caution: Hot!)

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Elodea canadensis (common pondweed)

∆ Fig. 2.45 The results below were gathered using this apparatus.

Gas bubbles given off in 5 minutes

Distance to lamp in cm 5 10 15 20 67 57 40 20

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Devise and plan investigations ➊ a) Explain why the rate of producing bubbles can be used as a measure of the rate of photosynthesis.

b) Explain how you would identify the gas produced by the plant.

Analyse and interpret data ➋ a) Use the data in the table to draw a suitable graph. b) Describe and explain the shape of the graph.

Evaluate data and methods ➌ Light is not the only factor that can affect the rate of photosynthesis. a) Which other factor might have had an effect on these measurements?

∆ Fig. 2.47 A plant with magnesium deficiency.

QUESTIONS 1. Explain why plants need a supply of mineral ions. 2. Describe the deficiency symptoms in a plant for the following mineral ions

a) nitrogen b) magnesium. 3. Explain why plants show the deficiency symptoms for

a) nitrogen and b) magnesium that you described in Question 2.

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b) Suggest how the method could be changed to avoid this problem.

∆ Fig. 2.46 A plant with nitrogen deficiency.

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MINERAL IONS IN PLANT GROWTH Photosynthesis produces carbohydrates, but plants contain many other types of chemical. Carbohydrates contain just the elements carbon, hydrogen and oxygen, but the amino acids that make up proteins also contain nitrogen. So plants need a source of nitrogen, which they take in in the form of nitrate ions. Other chemicals in plants contain other elements: for example, chlorophyll molecules contain magnesium and nitrogen. Without a source of magnesium and nitrogen, a plant cannot produce chlorophyll and so cannot photosynthesise. These additional elements are dissolved in water in the soil as mineral ions. Plants absorb the mineral ions through their roots, using active transport because the concentration of the ions in the soil is lower than in the plant cells. Plants that are not absorbing enough mineral ions show symptoms of deficiency. For example, a plant with a nitrogen deficiency has stunted growth, and a plant with magnesium deficiency has leaves that are yellow between the veins, particularly in older leaves as the magnesium ions are transported in the plant to the new leaves.

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Getting the best from the book continued

Improved yield can be produced in many ways: • increasing the size of the part of the plant we eat, such as seeds in wheat, maize and rice; tubers in potatoes and yams; leaves in cabbages • decreasing the size of the parts of the plant we do not eat, such as stalks in wheat, because less energy is then ‘wasted’ by the plant growing parts that we do not want and it is easier to harvest • improving pest and disease resistance, as less damage to the plant means it will grow faster • improved growth in adverse conditions, such as drought or cold • improving the taste or colour of the crop. Other factors can also help, such as reducing stalk length so that rice and wheat plants aren’t blown over as easily in strong winds and so are easier to harvest. SCIENCE IN CONTEXT

breeding programmes.

b) Explain why some characteristics cannot be bred for in selective breeding programmes.

2. Give three characteristics that have been selectively bred for in crop plants to improve crop yield.

3. For each of the characteristics you have given in Question 2, explain how these improve crop yield.

4. Explain why plants are selectively bred in horticulture. EXTENSION

One of the problems with selective breeding is that, when you breed from only a small number of individuals, you reduce not only the variation in the characteristics you are selecting for, but also the variation in other alleles. This means that you can lose other characteristics which might be useful in the future.

TULIP MANIA

For example, tulips were introduced to Europe in the 1500s from Turkey. They were so exotic that they became a luxury item that all wealthy people had to have. Plant breeders rapidly developed new varieties through selective breeding, such as flowers with different-coloured lines or specks on the petals. ∆ Fig. 5.19 A completely black flower is almost impossible to breed, but that does not stop people trying to produce it because many people would pay a lot of money for something so rare.

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Selective plant breeding is not all a success story. For example, rice plants from around the world were crossed in breeding experiments to produce so‑called ‘miracle rices’. But the plants required extra fertiliser and plenty of water to produce the high yields. The modern seeds were also very expensive. If conditions were not perfect, the new varieties could sometimes do worse than the traditional varieties, and in some countries productivity actually went down. Scientists began to appreciate how important the environment was to the way the genes worked. The old‑fashioned varieties had evolved over thousands of years to cope with local environmental conditions.

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At the peak of ‘tulip mania’ in the Netherlands in the 1630s, single tulip bulbs were being sold for more than 10 times the annual income of a skilled craftsman. Prices suddenly collapsed in 1637.

To protect against this, many wild varieties of rice, wheat, potatoes and other plants are collected and grown in ∆ Fig. 5.20 There are many wild varieties of rice, but we eat case we need their characteristics only a few varieties selectively bred for particular characteristics in the future. such as larger grain size. 1. Using what you know about sexual reproduction, suggest why the amount of variation between selected individuals is smaller than in wild populations of a plant. 2. Why is it useful that selectively bred varieties have only limited genetic variation? Explain your answer as fully as you can. 3. Why could it be a problem in the future that selectively bred varieties have only limited genetic variation? Explain your answer as fully as you can. 4. Growing wild varieties of crop plants to keep them for the future takes a lot of space and time to look after them. This space and time could be used to grow varieties that produce more food. Do you think it is worth keeping wild varieties like this? Explain your answer as fully as you can.

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Plants are also bred in horticulture, for gardens, for houseplants and cut flowers, to improve the colour, shape and form of the flowers and leaves. This is because people like new things.

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Science in context boxes put the ideas you are learning into a historical or modern context.

1. a) Explain why some characteristics can be bred for in selective

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QUESTIONS

coronary arteries

right atrium

left atrium

right left ventricle ventricle heart pulmonary artery lungs hepatic vein

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carotid artery

pulmonary vein

hepatic artery

liver

aorta hepatic portal vein

The circulatory system in mammals such as humans is a double circulatory system. This means that the blood flows twice through the heart for every one time it flows through the body tissues. The advantage of this is that the blood pressure in the circulation through the body can be kept higher than the blood pressure in the circulation through the lungs. A lot of force is needed to pump the blood down to the legs and back, but this force could damage the tiny capillaries in the lungs, which are much closer to the heart. BLOOD VESSELS The blood vessels are grouped into three different types: arteries, capillaries and veins.

artery: thick-walled, carrying blood at high pressure

REMEMBER

Remember: a for arteries that carry blood away from the heart. Veins carry blood into the heart and contain valves.

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mesenteric artery

gut

renal artery

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renal vein

oxygenated blood

deoxygenated blood

kidneys

legs and body

∆ Fig. 2.95 Plan of the human circulatory system.

REMEMBER

The heart muscles have their own blood supply: the coronary arteries that branch from the aorta and link to the coronary veins that drain into the right atrium.

∆ Fig. 2.96 Arteries vary in diameter vein:about 10 to 25 mm. from thin-walled, carrying blood at low pressure vein: thin-walled, carrying blood at low pressure

capillary:

Capillaries Capillaries are the tiny blood vessels that flow through every tissue and connect arteries to veins. Capillaries have very thin walls, which helps to increase the rate of diffusion of substances. All exchange of substances between the blood and tissues happens in the capillaries.

very small; the walls may be just one cell thick capillary: very small; the walls may be just one cell thick

∆ Fig. 2.97 Veins vary in diameter from about 5 to 15 mm. Capillaries are very small, with a diameter of around 0.01 mm.

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The name of a major blood vessel is often related to the organ it supplies: coronary for heart (from the Latin corona for ‘crown’ because the blood vessels surround the top of the heart like a crown), hepatic for liver (from the Greek hepatos meaning ‘liver’), renal for kidneys (from the Latin renes meaning ‘kidneys’), pulmonary for lungs (from the Latin pulmonis, ‘lungs’). Learn the names of these blood vessels that are associated with the heart, the lungs, liver and kidneys.

Arteries Arteries are large blood vessels that carry blood flowing away from the heart. Blood in the arteries is at higher pressure than in the other vessels. The highest pressure is in the aorta, the blood vessel that leaves the left ventricle. Arteries have thick muscular and elastic walls, with a narrow lumen (centre) through which the blood flows. The thick walls protect the arteries from bursting when the pressure increases as the pulse of blood enters them. The recoil of the elastic wall after the pulse of blood has passed through the artery helps to maintain the blood pressure and even out the pulses. By the time the blood enters the fine capillaries, the change in pressure during and after a pulse has been greatly reduced.

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vena cava

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heart muscles

coronary veins

Extension boxes take your learning even further.

EXTENSION

head

jugular vein

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Remember boxes provide tips and guidance to help you during the course and in your exam.

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The first question is a student sample with examiner’s comments to show best practice.

Exam-style questions

iii) The diagram illustrates the cross correctly, but lacks detail.

Sample student answer

EXAMINER’S COMMENTS

The best way of illustrating the cross is to use a Punnett square, showing each stage of the cross:

a) i) Correct identification, but the explanation should be more specific – The two letters making up the genotype are written in upper case.

a) The diagram shows a pair of chromosomes:

the genotypes of the parents the different alleles that could be passed on to the offspring from the mother and father (the alleles in the egg cells and sperm cells)

ii) This is a good answer. b) i) The answer is correct, but could be better worded. Rather than saying ‘the couple’, it is better to say that the man could be TT or Tt, and the woman could be TT or Tt.

genotype TT: can taste PTC

ii) Both statements are correct, but only two marking points have been addressed. The student is correct, that unless both parents were Tt, all children would be able to taste PTC, but the answer would benefit from two statements of explanation.

(2)

The letters are capitals

ii) Write down the other possible genotypes related to tasting PTC, along with their (2) phenotypes.

✓ 1

Tt - the phenotype is can taste PTC

First of all, it should be made clear that as both the man and woman can taste PTC, they must each have at least one T allele.

tt - the phenotype is cannot taste PTC

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There should then be a sentence of explanation to link the statements, such as:

or Tt

What does this tell you about the genotypes of the couple? Explain your answer fully. (4) The genotype of both the man and women must be Tt

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Because otherwise, all the children

would be able to taste PTC

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iii) Show the genetic cross involved.

the possible phenotypes produced.

Tt

Tt

(4)

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Mother possible alleles in eggs T t TT T can taste PTC

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TT

Tt

tT

tt

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(Total 14 marks)

Tt can taste PTC

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Tt tt t can taste cannot taste PTC PTC

A further point is the way in which the student has written the third possible genotype in their answer, as tT. Although not incorrect, the convention is to write the dominant allele first, so it should be written Tt.

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(2)

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ii) The couple have children. Their first child cannot taste PTC; the second one can.

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Without the presence of a t allele in both parents, all the children would be able to taste PTC.

i) Give the possible genotypes of the man and the woman. 1

The couple could be TT

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i) Is the allele for tasting PTC dominant or recessive? Explain your answer. 1 Dominant

the possible combinations of alleles in the offspring (genotypes)

Exam-style questions continued b) A couple who can both taste PTC have children.

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Question 1 People are either able to taste a chemical called PTC, or not. Being able to taste PTC is controlled by a single gene which has two alleles, T and t.

Father possible alleles in sperm

Each section includes examstyle questions to help you prepare for your exam in a focussed way and get the best results.

End of topic checklist

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A full checklist of all the information you need to cover the complete specification requirements for each topic.

Biomass is the mass of living material, such as the mass of a living organism.

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A decomposer is an organism that causes decay of dead material, such as many fungi and bacteria.

A food chain shows the sequence of a producer, a primary consumer that eats it, a secondary consumer that eats the primary consumer, and so on. A food web shows many interdependent food chains.

A primary consumer is an animal that eats plants (also a herbivore).

A producer is an organism that produces its own food, such as plants using light energy in photosynthesis to produce glucose.

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A pyramid of biomass diagram shows the biomass in different trophic levels of a food chain, often a pyramid shape. A pyramid of energy diagram shows the energy content of different trophic levels of a food chain, always a pyramid shape.

a) Is the lion a carnivore or herbivore? (2 marks) Explain your answer. b) At which trophic level does the zebra feed?

(1 mark)

c) Draw a food chain for the organisms shown in the photograph.

(2 marks)

d) Lions also feed on the herbivores gazelle and wildebeest. Use all these organisms to draw a food web for the African grassland.

(3 marks)

2. In a community of organisms in a garden there are 5 lettuces. There are 40 caterpillars feeding on the lettuces until 2 thrushes (insectivorous birds) eat all the caterpillars. a) Draw a pyramid of number for this community.

(3 marks)

b) Describe the limitations of this pyramid.

(2 marks)

A secondary consumer is an animal that eats primary consumers.

c) Describe the difficulty of preparing the data for a pyramid of biomass for (2 marks) these organisms.

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A pyramid of number diagram shows the number of individual organisms in different trophic levels of a food chain, often a pyramid shape.

A tertiary consumer is an animal that eats secondary consumers. A trophic level is a feeding level in a food chain or food web, such as producer, primary consumer.

3. Use the food web on page 271 to predict what would happen to the numbers of the following species if all the herbivorous insects were killed by insecticide. Explain your answers. a) predatory insects

(2 marks)

The facts and ideas that you should know and understand by studying this topic:

b) insectivorous birds

(2 marks)

c) mice

(2 marks)

❍ Different trophic levels include producers, primary consumers, secondary

d) snakes.

(2 marks)

consumers, tertiary consumers and decomposers.

End of topic questions allow you to apply the knowledge and understanding you have learned in the topic to answer the questions.

End of topic questions

1. The photograph shows lions feeding on the carcass of a zebra. When a lion catches a zebra, it will share the meat with other lions. Before the lion started chasing the zebra, the zebra had been feeding on grass.

❍ Food webs are made up of many interdependent food chains. ❍ Differences between trophic levels can be shown as pyramids of number, pyramids of biomass and pyramids of energy.

❍ Pyramids of energy are always a pyramid shape, but the other two kinds of pyramid diagrams may not always be so.

❍ Both substances and energy are passed along food chains. ❍ Energy transfer to the next trophic level is always a small proportion of the energy

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gained, about 10% on average.

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Around 1.9 million living species have been described and named on Earth. Around 350 000 of these species are classified as plants and around 1.37 million species are classified as animals. Over 66 000 of the animal species are vertebrates (they have bony skeletons), and the rest are invertebrates of which the majority (around 1 million species) are insects.

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STARTING POINTS 1. What are the characteristics shared by living organisms?

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It is difficult to know how many species are still to be discovered, although scientists reckon they have discovered most living mammals, birds and coniferous trees. The smaller the organism, the greater the chance that there are species we don’t yet know about. So although over 4000 species of bacteria have been identified, there could be more species of bacteria than of all the other kinds of organisms put together.

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2. Crystals can grow in size, but does that mean they are alive?

3. We talk of ‘feeding’ a fire when we add fuel, but does that mean fire is a living thing?

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4. Why is it useful to group organisms?

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5. What features are the most useful for grouping organisms?

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CONTENTS a) Characteristics of living organisms

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b) Variety of living organisms

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c) Exam-style questions

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The nature and variety of living organisms

∆∆Many species of different kinds of organisms live on a coral reef.

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Characteristics of living organisms INTRODUCTION

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Sometimes it is easy to tell when something dies: an animal stops moving around; a plant wilts and all the green parts collapse. But does a tree die in winter, when its leaves have dropped off? Are animals ‘dead’ when they hibernate underground for months? As technology gets increasingly sophisticated, and we can create machines with ‘brains’ and grow new organs in a laboratory, distinguishing between living and non-living could get even more difficult. We need a set of ‘rules’ that work for most organisms, most of the time.

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∆∆Fig. 1.1 Tiny tardigrades (about 1 mm long) are one of the toughest organisms known. They can survive temperatures below –200 °C, 10 days in the vacuum of space and over 10 years without water!

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KNOWLEDGE CHECK ✓✓Living organisms show a range of characteristics that distinguish them from dead or ­non-​­living material. ✓✓The life processes are supported by the cells, tissues, organs and systems of the body.

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LEARNING OBJECTIVES ✓✓Name the eight characteristics shown by living organisms. ✓✓Describe each of the characteristics of living organisms. ✓✓Explain that not all living organisms show every characteristic all of the time.

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THE EIGHT CHARACTERISTICS OF LIFE There are eight life characteristics that most living organisms will show at some time during their lives. • Movement: In all living cells, structures in the cytoplasm move. In more complex organisms, the whole structure may move. Animals may move their entire bodies; plants may move parts of their body in response to external stimuli ∆∆Fig. 1.2 Sunflowers follow the Sun as it moves across the sky through the day. such as light.

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• Respiration: This is a series of reactions that take place in living cells to release energy from nutrients. This energy is used for all the chemical reactions that keep the body alive. • Sensitivity: Living organisms are able to detect and respond to changes in their external and internal conditions. • Homeostasis: This is the control of internal conditions, to provide the best conditions inside cells for all the reactions needed for life to exist. For example, when we eat and drink we take in water – our body controls how much water is absorbed and removed from the blood, so that cell processes can continue to work efficiently. • Growth: This is the permanent increase in the size and/or dry mass (mass without water content) of cells or the whole body of an organism. Your mass changes throughout the day, depending on how much you eat and drink, but your growth is the amount by which your body increases in size when you take nutrients into cells to increase their number and size. As organisms grow, they may also change or develop. • Reproduction: This includes all the processes that result in making more individuals of that kind of organism, such as making gametes and the fertilisation of those gametes. • Excretion: Living cells produce many products from the reactions that take place inside them. Some of these are waste products – materials that the body does not use. For example, animals cannot use the carbon dioxide produced during respiration. Waste products may also be toxic, so they must be removed from the body by excretion. • Nutrition: The taking of nutrients, such as organic substances and mineral ions, into the body. Nutrients are the raw materials that cells need to release energy and to make more cells.

QUESTIONS

1. For each of the eight characteristics, give one example for:

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a) a human

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b) an animal of your choice c) a plant.

2. For each of the eight characteristics, explain why they are essential to a living organism.

REMEMBER

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An easy way to remember all eight characteristics is to take the first letter from each process. This spells MRS H GREN. Instead, you may make up a sentence in which each word begins with same letter as one of the processes: for example, My Revision System Here Gets Really Entertaining Now.

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EXTENSION

Not everyone agrees on whether viruses can be called living organisms.

protein coat DNA

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Viruses are very simple structures, consisting of an outer protein coat that protects the genetic material inside. They have no cell structures or cytoplasm, so they do not respire or sense their surroundings. They also do not take in substances to build more cells, or excrete anything. In many ways they behave like simple crystalline chemicals. However, when they infect a cell, such as a bacterial, plant or animal cell, they cause that cell to produce many copies of the virus. So they do reproduce.

∆∆Fig. 1.3 The structure of a virus.

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1. Which characteristic of living organisms do viruses have?

2. List the other characteristics of living organisms, and for each one describe what viruses can and cannot do.

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3. Using what you know about viruses, prepare an argument for classifying them as living organisms.

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4. Using what you know about viruses, prepare an argument for not classifying them as living organisms.

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REMEMBER

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Be prepared to make a decision and use your knowledge to argue your point of view about difficult examples such as viruses.

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End of topic checklist Excretion is the removal of waste (often toxic) substances that have been produced from chemical reactions inside the body, such as carbon dioxide and urea in animals. Growth is the permanent increase in body size and dry mass of an organism, usually from an increase in cell number or cell size (or both).

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Homeostasis is the maintenance of a constant internal environment, such as body water content and body temperature. Movement happens in all living cells: both plants and animals.

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Nutrition is the taking in of substances for use in the body as food or to make food.

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Reproduction is the production of new organisms.

Respiration is the chemical process in which glucose is broken down inside cells, releasing energy and producing carbon dioxide and water.

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Sensitivity refers to the detection of changes (stimuli) in the surroundings by a living organism, and its responses to those changes.

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The facts and ideas that you should know and understand by studying this topic: lives.

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❍❍All living organisms show the eight characteristics of life at some point in their ❍❍The characteristics of life are: movement, respiration, sensitivity, homeostasis,

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growth, reproduction, excretion and nutrition.

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End of topic questions 1. Name the eight processes of life. Try making up your own sentence to help you (9 marks) remember them all. 2. Name two life processes necessary for an organism to release energy.

(2 marks)

3. Explain why dry mass is used to measure growth.

(2 marks)

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4. When you place a crystal of copper(II) sulfate in a saturated solution of the same compound, the crystal will increase in size. Does this mean that the crystal is alive? (1 mark) Explain your answer. 5. Plants cannot move about, as animals can. Does that mean animals are more alive (2 marks) than plants? Explain your answer.

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6. During winter, an oak tree will lose its leaves and not grow. Is the tree still living during this time? Explain your answer using all the characteristics of life. (4 marks)

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Variety of living organisms

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∆∆Fig. 1.4 The tallest plants are giant redwood trees, capable of growing to over 90 m high.

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The many different kinds of living organisms come in a confusing variety of forms. Classifying (grouping) organisms using their similar characteristics helps us to make sense of all the variation. This information can help us understand which organisms are most closely related to each other, which groups have evolved from other groups, and which groups play the most important roles in an ecosystem.

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INTRODUCTION

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KNOWLEDGE CHECK ✓✓Living organisms show great variety. ✓✓Organisms can be classified according to their characteristics.

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LEARNING OBJECTIVES ✓✓Describe the common features shown by eukaryotic organisms: plants, animals, fungi and protoctists. ✓✓Describe the common features shown by prokaryotic organisms such as bacteria. ✓✓Understand the term pathogen and know that pathogens may include fungi, bacteria, protoctists or viruses.

PLANTS Plants are multicellular organisms, which means they are made up of more than one (usually thousands or millions) of cells. Plant cells have a cell wall as well as a cell membrane. The cell wall is made of cellulose and gives the cell shape and support. Many plant cells have a large central vacuole that contains cell sap, which is water with various substances dissolved in it. The vacuole may

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EUKARYOTES AND PROKARYOTES Living organisms are either eukaryotic or prokaryotic. Eukaryotic organisms have cells that contain a nucleus and other organelles such as mitochondria and chloroplasts. Plants, animals, fungi and protoctists are all eukaryotic organisms. Prokaryotic organisms have cells that are much smaller and simpler than eukaryotic cells. Prokaryotic cells do not contain a nucleus or organelles such as mitochondria or chloroplasts. Bacteria are prokaryotic organisms.

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also be a storage space for some substances. In a healthy plant the vacuole is large and helps support the cell when it is full of sap. Plant cells may contain chloroplasts, which are able to carry out photosynthesis – a process in which they use the Sun’s energy to produce carbohydrates. Carbohydrates, stored as starch or sucrose, store energy for the plant but can also be used as food by animals that eat plants. Plants vary greatly in size and shape, from tall rainforest trees to tiny flowers like violets. We use many plants as food, including cereals such as rice and maize, and herbaceous legumes such as lentils, peas and beans.

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QUESTIONS

1. Explain what is meant by the term multicellular, and give one example.

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2. Plants do not have skeletons, as animals do, but are still able to stand upright. Explain why.

3. One kind of structure found in some plant cells makes plants

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able to produce their own food. What is this structure called?

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ANIMALS Animals are multicellular organisms. Unlike plants, their cells do not contain chloroplasts and so cannot carry out photosynthesis. This means that they have to eat other organisms (plants or other animals) to get their food. Animal cells have a cell membrane but no cell wall. Many animals are able to coordinate their movement using nerves and are able to move from one place to another. For energy, animals also store carbohydrates, often in the form of glycogen. They also store lipids, often as a layer of fat below the skin or around body organs, as a store of energy. As with plants, the variety of animals is huge, from enormous whales and elephants to tiny ants. ▷▷Fig. 1.5 Ants belong to the insects, as do the housefly and mosquito. Whales and elephants are classified as mammals, as are humans.

QUESTIONS 1. If you compared a plant cell and an animal cell under the ­microscope, which features would you see:

a) in both cells 16

b) only in the plant cell?

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2. Describe two differences between plants and animals in terms of the structure of their bodies.

3. One difference between plants and animals is that many animals can move from place to place, but plants cannot. Explain this difference.

bud (this is how the cell multiplies, bits bud off as separate daughter cells)

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nucleus

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2 µm

cell wall

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FUNGI Some fungi (such as yeast) are ­single-​­celled but most have a structure consisting of fine threads known as hyphae. Each hypha may contain many nuclei. Several hyphae together form a mycelium. Many fungi can be seen without a microscope. Their cell walls are made of chitin, a fibrous carbohydrate which is different to the cellulose used in plants. Their cells do not contain chlorophyll so they cannot carry out photosynthesis. To obtain energy they secrete digestive enzymes outside the cells (extracellular secretion), onto living or dead animal or plant material, and absorb the digested nutrients. This is called saprotrophic nutrition. Like animals, fungi may store carbohydrate in the form of glycogen.

vacuole

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mitochondrion

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cell membrane

∆∆Fig. 1.6 The internal structure of a yeast cell that is reproducing by budding.

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spore case

yeast cell

wall of chitin cell membrane vacuole

nuclei

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cytoplasm

hyphae forming mycelium

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Mucor

part of fungal hypha

∆∆Fig. 1.7 Left: the mycelium and spore cases of Mucor, a mould. Right: detail of a hypha of Mucor.

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Examples of fungi include yeast, a ­single-​­celled fungus used by humans in baking, and Mucor, a fungus with the typical hyphal structure. Mucor is often seen as a mould growing on spoiled foods. Some species of fungi are pathogens, which means they cause disease in other organisms. For example, ringworm is caused by a fungus that produces rings of itchy skin in humans. Also many plants are damaged by rusts and moulds which are different kinds of fungi.

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MUSHROOMS AND TOADSTOOLS

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We normally think of a mushroom or toadstool as the whole of a fungus, because this is usually all we can see. However, these are only the reproductive organs, where spores are produced. The mycelium of the fungus is usually hidden below ground or within rotting materials, where it is moist and where the hyphae can digest the surrounding tissue and absorb the nutrients that are released. The reproductive structures have to be large enough so that the wind can carry the spores away to other places, and tough enough to survive the drying conditions of the air until the spores have been dispersed.

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● SCIENCE IN CONTEXT

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▷▷Fig. 1.8 A mushroom or toadstool is only the visible part of this fungus. The rest of the structure is hidden from view.

QUESTIONS

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1. Which characteristics do fungi share with a) plants and

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b) animals?

2. Describe what is meant by saprotrophic nutrition and how

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it differs from the way animals get their nutrition.

3. Most people think of toadstools and mushrooms as the main

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part of fungi. Explain why this is incorrect.

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PROTOCTISTS Protoctists are also ­single-​­celled microscopic organisms, usually much larger than bacteria. Their cells contain a nucleus and many have features of animal cells or plant cells. One example is Amoeba, which looks like an animal cell and is found in ponds and feeds on other microscopic organisms. Other protoctists, such as Chlorella, look more like plant cells because they contain chloroplasts and so can photosynthesise. A few protoctists are pathogens, such as Plasmodium, the organism that causes the disease malaria in humans.

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nucleus

cell wall cell membrane

cell membrane chloroplast nucleus

food vacuole

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contractile vacuole

∆∆Fig. 1.9 Amoeba and Chlorella.

● SCIENCE IN CONTEXT

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MALARIA

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Malaria is one of the greatest causes of death from infectious illness in the world today. Around 750 000 people die of the disease each year, mostly young children and mostly in ­sub-​­Saharan Africa. The disease is caused by the protoctist Plasmodium, which has a clever way of getting from one person to the next: it hitches a lift in the alimentary canal of an Anopheles mosquito. The female mosquitoes suck blood from humans to provide the nutrients they need to lay eggs. As a mosquito pierces into a blood vessel, it inserts a little liquid to prevent the blood from clotting. If the mosquito has fed recently on a person infected with Plasmodium, this liquid will contain some of the parasites and so infect the new person. This protects the protoctist from the harsh conditions of the environment and allows it to be passed on to a new host.

QUESTIONS

1. Explain why some protoctists were once classified as plants and others as animals.

2. What features do all protoctists have in common? 3. Is it correct to describe mosquitoes as the cause of malaria?

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Explain your answer.

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BACTERIA Bacteria are ­single-​­celled, microscopic organisms that are smaller than plant and animal cells and come in many different shapes. Their cells have no nucleus, so the single circular chromosome of DNA lies free in the cytoplasm inside the cell. Many bacteria have additional circles of genetic material, called plasmids. Bacterial cells are surrounded by a cell membrane and cell wall, although in different groups of bacteria the cell wall is made of different chemicals. Some bacteria can carry out photosynthesis but most feed ∆∆Fig. 1.10 General structure of a bacterial cell. off other living or dead organisms. Some bacteria are useful to humans. For example, Lactobacillus bulgaricus, a ­rod-​­shaped bacterium, is used to make yoghurt from milk. Other bacteria are pathogens, causing diseases in plants and animals. An example of a pathogen is Pneumococcus, a spherical bacterium that can cause pneumonia in humans. Azotobacter

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Staphylococcus

Spirillum

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200 µm

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Salmonella

BACTERIAL PLASMIDS

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● SCIENCE IN CONTEXT

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∆∆Fig. 1.11 Different bacteria can be recognised from their shape and structure.

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Bacterial plasmids have become very useful to us in genetic engineering, where they are used as vectors (see Topic 5c: Genetic modification (genetic engineering)). Not all bacteria have them, but those that do transfer these small circles of genetic material to other bacteria quite easily. Plasmids may even be transferred between bacteria of different species. This is not true reproduction as the transfer is not of the main chromosome and may not lead to production of new individuals. However, this kind of transfer may be important in the spread of antibiotic resistance between bacterial species, because some of the genes for antibiotic resistance are found in the plasmids.

QUESTIONS 1. Describe three differences between a plant cell and a bacterial cell. 2. Compare the structure of bacteria and protoctists.

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3. How are bacterial chromosomes different from the chromosomes of eukaryotes?

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RNA

protein coat

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protein coat

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VIRUSES Viruses are small particles rather than cells. They have a wide variety of shapes and sizes, but they all consist of a protein coat containing one type of nucleic acid, either DNA or RNA. They are even smaller than bacteria: they may only be seen with an electron microscope. Viruses are parasites and can only reproduce inside the living cells of an organism they have infected. They are not living organisms themselves: although they can reproduce, they do not show other characteristics of life. There are viruses that can infect every type of living thing. Many viruses are pathogenic and cause disease in the organisms they infect. The tobacco mosaic virus is a plant virus. It prevents the formation of chloroplasts in the tobacco plant cells, which causes discolouring of the leaves. Influenza viruses are a group of many closely related viruses that can cause ‘flu’ in many different animals including humans. The human immunodeficiency virus (HIV) causes the disease called AIDS (acquired immune deficiency syndrome) in humans.

100 nm

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RNA or DNA

100 nm

bacteriophage

HIV virus

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flu virus

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∆∆Fig. 1.12 Some viruses. 1 m = 1000 mm (millimetres). 1 mm = 1000 µm (micrometres). 1 µm = 1000 nm (nanometres).

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HIV AND AIDS

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SCIENCE IN CONTEXT

The HIV virus is one of a group of viruses that attack and destroy cells in the immune system. This leaves the body open to infection by other pathogens – in the case of HIV, this causes the disease called AIDS. Many AIDS patients do not die from the HIV virus, but from other diseases such as tuberculosis (caused by a bacterium) that take advantage of the weak immune system.

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The HIV virus does not survive well outside the body and is mainly transmitted from one person to another through body fluids. The most common transmission is during sexual intercourse. However,

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transmission in blood is also possible, such as through blood transfusion, or sharing of injection needles between drug users. An infected mother can pass the HIV virus to a fetus in her uterus through the placenta, or through breast milk after birth.

QUESTIONS 1. Describe the basic structure of a virus. 3. Compare the size of a virus with the size of a bacterium. EXTENSION

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2. Why are viruses described as particles rather than cells?

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The five groups of living organisms described here are often defined as the five kingdoms of organisms, where a kingdom is the largest group in biological classification. Kingdoms are subdivided into increasingly smaller groups: • kingdom • phylum • class • order • family • genus • species by the characteristics of the organisms within the groups until, at the lowest level, there is only one species. A species is a group of individuals that share most of their characteristics and are capable of breeding with each other to produce fertile offspring.

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End of topic checklist A chloroplast is an organelle found in plant cells and some protoctist cells that can capture energy from light for use in photosynthesis. A hypha is a single thread of fungal mycelium (plural hyphae). A mycelium is a mass of hyphae that form the body of a fungus.

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A pathogen is an organism that causes disease in another living organism. Pathogens occur in fungi, bacteria, protoctists and viruses. A plasmid is a small circle of genetic material found in some bacteria in addition to the circular chromosome.

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Saprotrophic nutrition is the digestion of dead food material outside the body, as in fungi.

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The facts and ideas that you should know and understand by studying this topic:

❍❍Organisms are grouped by their common features into the major groups:

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eukaryotes, consisting of plants, animals, fungi and protoctists; prokaryotes, consisting of bacteria; and viruses.

❍❍Plants are multicellular organisms that have cells with cell walls, vacuoles and may

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have chloroplasts. They photosynthesise to make their food and store carbohydrate as starch or sucrose.

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❍❍Animals are multicellular organisms that do not have chloroplasts so they cannot photosynthesise; they usually can move and have a nervous system; and store carbohydrates, often as glycogen.

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❍❍Most fungi are made from multicellular hyphae, though a few, like yeast, are

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­single-​­celled. The cells have no chloroplasts, so fungi feed by saprotrophic nutrition; their cells have cell walls and may store carbohydrate as glycogen.

❍❍Protoctists are microscopic, ­single-​­celled organisms; some have no chloroplasts

and feed off other organisms, others have chloroplasts and can photosynthesise.

❍❍Bacteria are microscopic, ­single-​­celled organisms that have no nucleus; they have a circular chromosome and some may have additional genetic material in plasmids; they have cell walls and most feed off other living or dead organisms.

❍❍Viruses are infective particles made of a protein coat surrounding nucleic acid; they have no true cell structure and can only reproduce when inside a cell of another organism. cause disease in other organisms.

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❍❍The groups of fungi, bacteria, protoctists and viruses all contain pathogens, which

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End of topic questions 1. Put the following organisms into size order, starting with the smallest: bacteria protoctists viruses

(2 marks)

2. Copy and complete the table below to compare the different groups of organisms. (20 marks) Key cell structures

Food store

Other ­distinguishing features

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Multicellular or ­single-​­celled

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plants animals fungi bacteria protoctists viruses

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3. Explain why a large tree and a crop such as rice or maize are both classified (2 marks) as plants.

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4. A new organism is discovered. It is formed from cells that have no cell wall and (2 marks) no chloroplasts. Which group should it be classified in and why?

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5.  a) State what is meant by the term pathogen.

(1 mark) (4 marks)

c) Name the disease each example causes.

(4 marks)

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b) Give one example of a pathogen from each of the following groups: fungi, ­bacteria, protoctists, viruses.

(2 marks)

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6. Explain why all viruses are parasitic (live off other living organisms).

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7. Before fungi were classified in their own separate group, they were sometimes grouped with plants and sometimes with animals. (2 marks)

b) Suggest why they are no longer classified with either plants or animals.

(2 marks)

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a) Explain why they could be grouped either way.

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­Exam-​­style questions

EXAMINER‘S COMMENTS

Sample student answer

a) i) It is important to know the features of different groups of organisms and be able to label these.

A: Correct B: Correct C: Incorrect – the outer layer of the hypha is the wall D:  Incorrect – the membrane is the next layer within the wall, pushed up against the wall. E:   Correct

B

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A

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The diagram shows the structure of a part of an organism called Mucor.

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Question 1

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a) i) Name each of the parts, ­A–​­E. Use the words in (5) the box below.

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cytoplasm membrane ­ nucleus

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The answer is correct in that the hyphae have a wall, but this cannot be described as a ‘cell wall’ as the hyphae are not divided into cells. The student simply had to repeat this information from part a) i) to be absolutely correct.

starch grain

vacuole

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nucleus

B

vacuole

C

membrane

D

wall

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cytoplasm

wall

✓ ✓ ✗ ✗ ✓

ii) Give two features the organism has in common with plants.

(2)

Mucor has a large central vacuole

Mucor has a cell wall

iii) Give one feature that tells you that Mucor is a fungus. It has many nuclei lying in the cytoplasm.

✓ (1)

✓ 25

D

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ii)   Correct – the hyphae of moulds such as Mucor have a large central vacuole.

iii) Correct. The student could have chosen from a selection of features but was only asked to give one.

E

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­Exam-style questions continued

Mucor lives on its food, e.g. bread, and secretes enzymes into it.

The food is absorbed over the surface of the fungus.

c) Yeast is another type of fungus. State one major difference between Mucor (1) and yeast. Yeast is ­single-​­celled.

✓ (Total 13 marks)

c) Correct – the mycelium of Mucor has many nuclei distributed through the cytoplasm, with no cell boundaries; yeast is made up of single cells.

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b) The answer is correct, but the student could have added that food is digested outside the mould, and that this process is called saprotrophic nutrition.

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(4)

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b) Describe how moulds such as Mucor feed.

Question 2

This question is about the variety of living organisms.

A: Amoeba

B: Chlorella

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a) Five types of living organism are listed ­A–​­D below. C: Lactobacillus

D: Pneumococcus

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i) Which two organisms are protoctists?

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ii) Which organism is a pathogen?

(2) (1)

iii) Which organism has chloroplasts?

(1)

iv) Which two organisms are bacteria?

(2) (1)

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v) Which organism is used to produce yoghurt?

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­Exam-style questions continued b) The diagram below shows the structure of one of the stages in the life cycle of Plasmodium.

C

A

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mitochondria

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B

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i) Name each of the parts, ­A–​­C.

(3)

ii) Explain one way that you can tell that Plasmodium is not a type of bacteria.

(Total 11 marks)

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Question 3

a) Name two examples of a flowering plant, to include one cereal crop and one legume.

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(2)

b) Name two examples of animals, to include one mammal and one insect.

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(4)

(Total 4 marks)

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Not everyone agrees that viruses should be called living things. Use your knowledge of viruses, and the characteristics of living things, to discuss whether or not viruses should be classed as living.

Question 4

(1)

(2)

c) Plants and animals respond to their surroundings. i) Name a body system that animals use to respond to their surroundings.

ii) Describe one way that plants can respond to their surroundings.

(1) (1)

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(Total 6 marks)

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When we talk about the ‘heart’ of something, in a general way, we mean the centre of something – not only where it is, but also the role it plays. And for good reason: the human heart is not only positioned in the middle of the body; it also plays a central role in maintaining life.

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STARTING POINTS 1. How is the body organised so that it can carry out the life processes effectively?

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The heart and circulatory system function to circulate blood around the body and so deliver oxygen from the lungs, and nutrients from the digestive system, to all cells so that they can respire and carry out all the processes needed for life. The blood then removes waste products from these processes, for example delivering carbon dioxide to the lungs and urea to the kidneys for excretion and removal from the body. The heart plays a central role in staying alive and staying healthy.

2. What do all cells have in common, and how are some cells different from others?

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3. What are the basic molecules of life?

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4. How do cell membranes control what can get into and out of the cell?

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5. How do plants and humans get the food they need for growth?

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6. What is cellular respiration and how do the body systems support it? 7. How are gas exchange surfaces adapted for rapid exchange of gases into and out of the body?

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8. How are materials transported around the bodies of plants and humans?

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9. What are the waste materials of metabolism and how are they removed from the body?

10. How do plants and humans respond to changes in the environment around them?

SECTION CONTENTS a) Level of organisation

f) Respiration

b) Cell structure

g) Gas exchange

c) Biological molecules

h) Transport

d) Movement of substances into and out of cells

i) Excretion

e) Nutrition

k) Exam-style questions

j) Coordination and response

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Structure and functions in living organisms

∆∆Microscopic view of leaf surface of spiderwort, showing cells.

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Level of organisation INTRODUCTION

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Bringing together similar activities that have the same purpose can make things much more efficient. For example, bringing teachers and students together in a school helps more students to learn more quickly than if each teacher travelled to each student’s home for lessons. The same is true in the body. Having groups of similar cells in the same place – as a tissue, and grouping tissues into organs, helps the body carry out all the life processes much more efficiently and so stay alive.

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∆∆Fig. 2.1 The human body is made up of several systems of grouped organs, including the digestive system, the nervous system, the muscle/skeletal system and the respiratory system.

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KNOWLEDGE CHECK ✓✓Describe the terms tissue, organ and body system. ✓✓Describe how the organisation of tissues, organs and body systems contributes to the eight life processes.

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LEARNING OBJECTIVES ✓✓Describe the levels of organisation in organisms: organelles, cells, tissues, organs and systems.

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CELLS AND ORGANELLES The cells that make up organisms all have certain things in common. Each cell is surrounded by a cell membrane. Inside the cell membrane is a ­jelly-​­like substance called the cytoplasm. Cells may be specialised to carry out particular roles, such as secreting enzymes or carrying electrical impulses. Within the cytoplasm are structures called organelles. The most obvious organelle is usually the nucleus, which contains the cell’s genetic material. Other organelles, such as chloroplasts and vacuoles, have specific roles within the cell.

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muscle tissue

heart

circulatory system

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muscle cell

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∆∆Fig. 2.2 The human body is organised at cell level. Muscle cells are found in muscle tissue, which may be found in the heart, which is part of the circulatory system.

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TISSUES In multicellular organisms, most cells are specialised and are organised into tissues. A tissue is a group of similar cells with the same function. Muscle cells, for example, are specially adapted to produce movement and are arranged in large groups to make muscle tissue; nerve cells transmit impulses from one nerve cell to another and are organised into nervous tissue such as the brain, spinal cord and nerves. In plants, the cells are also organised into tissues, such as xylem tissue, which forms long tubes that transport water through a plant; epidermal tissue that covers surfaces; and mesophyll tissue, which packs the spaces between other tissues.

QUESTIONS

1. Give two examples of organelles. 2. a) Give two examples of tissues in the human body. b) Explain how they are adapted for their function. 3. a) Give two examples of tissues in a plant.

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b) Explain how they are adapted for their function.

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ORGANS Organs are structures within larger organisms that are adapted to do a specific function. They are formed from different tissues that work together to carry out that function. For example, the function of the stomach is to digest food. To do this, secretory tissue lining the stomach produces enzymes to break down the food. In the wall of the stomach there is muscle tissue that contracts and relaxes. This helps to churn up the food in the stomach, to mix it with the enzymes and moves the food through to the intestines. Other organs in the human body include the heart, liver, lungs and kidneys. In plants, leaves are the organs adapted for photosynthesis, and flowers are the organs that are adapted for reproduction.

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SYSTEMS Organs like the stomach form part of larger structures called systems. The stomach is part of the digestive system, which has many parts including the teeth, the oesophagus and the intestines. Other systems in the human body include the nervous system, the circulatory system and the reproductive system.

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∆∆Fig. 2.3 The human digestive system.

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QUESTIONS 1. Give two examples of organs in the human body, and describe their function.

2. Give two examples of organs in a plant, and describe their function.

3. Explain what we mean by a body system.

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REMEMBER

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As you study body systems in more detail through your course, remember to identify the organs, tissues and cell types involved in each system, so that you build a range of examples that you can use to answer questions with.

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End of topic checklist An organelle is a structure within a cell that carries out a particular function, such as a nucleus or vacuole. A tissue is a group of similar cells that have a similar function, such as muscle tissue.

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An organ is a group of tissues that work together to carry out a particular function, such as the stomach or the heart. A system is a group of organs that work together to carry out a particular function, such as the mouth, stomach and intestines in the digestive system.

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The facts and ideas that you should know and understand by studying this topic:

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❍❍Within the body, organelles are found in cells, cells are grouped into tissues, tissues are grouped into organs and organs are grouped into systems.

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❍❍Give examples of organelles, cells, tissues, organs and systems. ❍❍These levels of organisation help the body to function efficiently.

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End of topic questions 1. Put the following in order of size, starting with the largest: cell   system   organ   tissue

(3 marks)

2. Write definitions for each of these words: (1 mark)

b) organ

(1 mark)

c) system

(1 mark)

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a) tissue

3. Give one example of each of the following in a) a plant and b) a human: cell tissue organ

4. Draw a table with the following headings. Function

Organs in this system

Tissues in these organs

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System

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(6 marks)

Cells in these tissues

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Complete your table as fully as you can, using up to three examples of systems in the human body. (max. 15 marks)

upper epidermis

palisade tissue cells contain many chloroplasts

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5. The diagram shows part of a leaf, which is a plant organ. The diagram is labelled to show some of the tissues. Describe the functions of the tissues in this organ. (4 marks)

xylem tissue

mesophyll tissue

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lower epidermis

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Cell structure INTRODUCTION

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It’s an amazing fact that the basic structure of a ‘complex cell’ (one that contains a nucleus) is the same in all animals, plants and protoctists on Earth. Scientists say that this is because they have all evolved from a single complex cell. This cell evolved from a simple ­bacteria-​­like cell (without a nucleus) around 2 billion years ago. This is the origin of all the millions of different species of plants, animals and protoctists that live on Earth today.

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∆∆Fig. 2.4 All plant, protoctist and animal cells (apart from some very specialised cells) have a cell nucleus like this human cheek cell.

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KNOWLEDGE CHECK ✓✓Most organisms are formed from many cells. ✓✓Cells may be specialised in different ways to carry out different functions.

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LEARNING OBJECTIVES ✓✓Describe cell structures, including the nucleus, cytoplasm, cell membrane, cell wall, mitochondria, chloroplasts, ribosomes and vacuole. ✓✓Describe the functions of the nucleus, cytoplasm, cell membrane, cell wall, mitochondria, chloroplasts, ribosomes and vacuole. ✓✓Know the similarities and differences in the structure of plant and animal cells. ✓✓Explain the importance of cell differentiation in the development of specialised cells. ✓✓Understand the advantages and disadvantages of using stem cells in medicine.

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PLANT AND ANIMAL CELLS The diagrams below show a typical animal cell and typical plant cells. These cells all have a nucleus, cytoplasm, cell membrane, mitochondria and ribosomes.

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Animal cell

Plant cells Both animal cells and plant cells have:

Only plant cells have:

cell membrane

cell wall

cytoplasm ribosomes

large vacuole

nucleus

chloroplasts

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mitochondria

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∆∆Fig. 2.5 The basic structures of an animal cell and plant cells.

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QUESTIONS

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• The cell membrane holds the cell together and controls substances entering and leaving the cell. • The cytoplasm is more complicated than it looks. It contains many small organelles and is where many different chemical processes happen. • The nucleus contains genetic material in the chromosomes. These control how a cell grows and works. The nucleus also controls cell division. • The mitochondria are organelles within the cytoplasm. They are the site of respiration. • Ribosomes are very small organelles. They are where proteins are made (protein synthesis).

1. a) Using the photograph in the Introduction, make a careful

drawing of the cell using a sharpened pencil to make clear lines.

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b) Use Fig. 2.5 to help you label your drawing to show the

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nucleus, cytoplasm and cell membrane.

chloroplast large vacuole

nucleus

∆∆Fig. 2.6 Plant mesophyll cells as seen under a light microscope.

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Plant cell structure Plant cells also have features that are not found in animal cells, such as a cell wall made of cellulose that supports the cell and defines its shape. Many plant cells have a large central vacuole in the cytoplasm that contains cell sap. The vacuole is used for storage of some materials, and to support the shape of the cell. If there is not enough cell sap in the vacuole, the cell may collapse and the whole plant may wilt.

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Many plant cells also contain organelles called chloroplasts. These contain the green pigment chlorophyll, which absorbs the light energy that plants need to make food in the process known as photosynthesis.

QUESTIONS 1. Name the part of a plant cell that does the following: a) carries out photosynthesis c) stops the cell swelling if it takes in a lot of water.

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Developing investigative skills

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b) contains cell sap

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The photograph shows the view of some cells seen through a light microscope.

red blood cell

white blood cell

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slide on a microscope so that the image is clearly focused. b) Describe and explain what precautions should be taken when viewing a slide at high magnification. c) Describe what precaution should be taken if using natural light to illuminate the slide, and explain why this is important.

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Demonstrate and describe techniques ➊➊ a) Describe how to set up a

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∆∆Fig. 2.7 Real light micrograph of red and white blood cells.

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Make observations and measurements ➋➋ a) Draw and label a diagram of the white blood cell shown in the light micrograph above.

b) If the ×4 eyepiece was used, and the ×20 objective, calculate the magnification of the image compared with the specimen on the slide.

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Analyse and interpret data ➌➌Are the cells shown plant cells or animal cells? Explain your answer.

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cell membrane cell wall vacuole

root hair

cytoplasm

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nucleus

◁◁Fig. 2.8 Plant root hair cells have a large surface area to absorb water and mineral ions from the soil.

cytoplasm nucleus

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cell membrane

INTERNATIONAL GCSE: BIOLOGY

CELL DIFERENTIATION AND SPECIALISED CELLS Single-celled organisms obviously do not have tissues, organs or systems. Their single cell carries out all the life processes. In multicellular organisms, because the cells can support each other, they can develop differently. This is called cell differentiation. This means different cells can become specialised for particular purposes, such as contraction in muscle cells or the ability to carry oxygen in red blood cells.

◁◁Fig. 2.9 Nerve cells can be very long to carry electrical impulses from one part of the body to another.

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nerve ending

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∆∆Fig. 2.10 A range of different cells from the human body. Left: A fat cell, with the nucleus in purple. Right: red blood cells and a white blood cell.​

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STEM CELLS Cells that have not yet differentiated are called stem cells. As an embryo develops, to begin with the cells are all very similar, but as these stem cells continue to divide, they differentiate and develop into all the different types of specialised cells found in the adult. In adults, there are also still some stem cells but they are not able to differentiate into as many types of cells as embryo stem cells. For example, adult human stem cells found in the bone marrow can differentiate into red blood cells, white blood cells and platelets. Stem cells have the potential to treat a range of medical conditions. For example, bone marrow can be taken from a donor and given to a patient to help treat leukaemia (blood cancer). Stem cells in the bone marrow differentiate into new healthy blood cells. Stem cells may also have the potential to treat other conditions such as diabetes, arthritis, Parkinson’s and Alzheimer’s disease. There are also some disadvantages to using stem cells, for example a patient’s own immune system may attack the stem cells. This is called rejection. There may also be other as yet unknown long-term side effects.

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INTERNATIONAL GCSE: BIOLOGY

QUESTIONS

1. Look at Fig. 2.9, the diagram of a nerve cell. Describe how it is specialised for its function.

2. Where possible, bone marrow transplants to treat leukaemia are

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taken from close relatives of the patients. Suggest why this is.

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End of topic checklist The cell membrane is the structure surrounding cells that controls what enters and leaves the cell. A cell wall of cellulose surrounds plant cells, giving them support and shape. Chloroplasts are organelles found only in plant (and some protoctist) cells and are where photosynthesis takes place in the cell.

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Chromosomes are long DNA molecules found in the nucleus of a cell.

Cytoplasm is the ­jelly-​­like liquid inside the cell which contains the organelles and where many chemical reactions take place.

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Mitochondria (singular mitochondrion) are organelles in plant and animal cells, and are where respiration takes place.

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The nucleus is the organelle in plant and animal cells that contains the genetic material.

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Photosynthesis is the chemical process by which plants use light, water and carbon dioxide, to create glucose and oxygen.

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Ribosomes are small organelles found in cells, and are where protein synthesis takes place. Specialised cells develop by the process of cell differentiation.

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Stem cells are cells that have not yet differentiated. They have many potential medical uses.

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A large vacuole is found in the middle of many plant cells, and contains cell sap.

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The facts and ideas that you should know and understand by studying this topic:

❍❍Structures inside cells include the nucleus, cytoplasm, cell membrane, mitochondria, ribosomes, cell wall, chloroplasts and vacuole.

❍❍The nucleus, cytoplasm, cell membrane, mitochondria, ribosomes, cell wall, chloroplasts and vacuole, have specific roles in cells.

❍❍Plant and animal cells have many structures in common, but plant cells also have ❍❍Stem cells can develop into specialised cells by the process of differentiation. ❍❍There are advantages and disadvantages of using stem cells in medicine.

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cell walls, and may have chloroplasts and large central vacuoles that animal cells do not have.

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End of topic questions 1. Describe the role of the following cell structures: a) nucleus

(1 mark)

b) cell membrane

(1 mark)

c) cytoplasm

(1 mark)

d) mitochondria

(1 mark)

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e) ribosomes.

(1 mark)

2. Draw a table to compare the structures found in plant and animal cells.

(16 marks)

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3. Here are some examples of statements written by students. Each statement contains an error. Identify the error and rewrite the statement so that it is correct.

b) All plant cells contain chloroplasts.

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a) Animal cells are surrounded by a cell wall that controls what enters and leaves (1 mark) the cell. (1 mark)

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c) Both animal cells and plant cells contain a large central vacuole in the middle of (1 mark) the cell.

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4. Red blood cells are unusual because they contain no nucleus. When they are damaged, they have to be replaced with new cells from the bone marrow. (2 marks) Explain how this is different from other cells.

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5. State what is meant by the term cell differentiation.

(1 mark)

6. Describe one advantage and one disadvantage of using stem cells in medicine. (2 marks)

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