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Poster: "ECR 2012 / C-0867 / MR aspects of Paget's disease of the breast: role in the staging of disease" by: "I. Baglio1, G. Carbognin2, F. Dal Corso1, A. Bucci1, V. Girardi3, R. Pozzi Mucelli1; 1Verona/IT,... more
Poster: "ECR 2012 / C-0867 / MR aspects of Paget's disease of the breast: role in the staging of disease" by: "I. Baglio1, G. Carbognin2, F. Dal Corso1, A. Bucci1, V. Girardi3, R. Pozzi Mucelli1; 1Verona/IT, 2Brescia/IT, 3Peschiera Del Garda/IT"
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Purpose: To evaluate location and pathological outcome of breast MRI suspicious lesions in patients with newly diagnosed ipsilateral/controlateral breast cancer. Methods and Materials: Among 310 consecutive pre-operative breast MRI, 71... more
Purpose: To evaluate location and pathological outcome of breast MRI suspicious lesions in patients with newly diagnosed ipsilateral/controlateral breast cancer. Methods and Materials: Among 310 consecutive pre-operative breast MRI, 71 lesions (evident on MR images, non-palpable, first-look ultrasound and mammographically occult) were recommended for second-look ultrasound. The retrospective evaluation included second-look ultrasound identification according to lesion's location (ipsilateral - in the same/different quadrant - controlateral), distance from the primary lesions (4 cm). Results were correlated with pathological findings. Results: Of 50 lesions depicted at second-look ultrasound, 26 lesions were ipsilateral to the known cancer and 24 were controlateral. Overall, 16/26 (61%) ipsilateral lesions were malignant. Of the 26 ipsilateral lesions, 12 (24%) were in the same quadrant as the index cancer, of which 8 (66%) were malignant (4-ILC, 3-IDC, 1-DCIS) and 4 were benign. The remaining 14/26 (28%) ipsilateral lesions were in different quadrant from the known cancer; 8 (57%) were malignant (5-ILC, 3-DCIS) and 6 were benign. Of the 24 controlateral lesions to known cancer, 4/24(16%) were malignant (2-ILC, 2-IDC). Overall, of the 20/50 (40%) malignant lesions identified by second-look ultrasound, 13/20 (65%) were within 4 cm distance from the primary (p < 0.05). Conclusions: Second look ultrasound identified 71 % of incidental breast MRI lesions in newly diagnosed breast cancer patients, of which 40 % proved malignant. The majority (65%) of additional tumour foci are in the same quadrant and within 4 cm of the index cancer. At a minimum, when performing ultrasound in a patient known to have cancer, thorough evaluation of at least that quadrant of the breast is recommended
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Ultrasonography (US) is the choice morphological imaging modality in the study of thyroid carcinomas. The present technological evolution (high frequency probes, development of Colour-Doppler) allows the detection of small non-palpable... more
Ultrasonography (US) is the choice morphological imaging modality in the study of thyroid carcinomas. The present technological evolution (high frequency probes, development of Colour-Doppler) allows the detection of small non-palpable nodules, being able to define, in a high percentage of cases, features pointing to the malignant character of a thyroid mass, although the definite assessment of malignancy (invasion of adjacent structures, metastatic cervical nodes) is quite rare. From a diagnostic viewpoint US is required to identify nodules with suspect features, to be submitted to fine needle aspiration biopsy. Moreover, US plays a basic role in the staging--at the cervical level--of carcinomas as well as in the post-operative follow-up. The other imaging modalities (Computed Tomography, Magnetic Resonance Imaging) play a limited role in both staging and post-operative follow-up.
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Intraductal papillary mucinous tumor (IPMT) of the pancreas was identified and classified only recently. IPMT has a primarily intraductal, papillomatous growth pattern, which is associated with excessive mucin secretion and results in... more
Intraductal papillary mucinous tumor (IPMT) of the pancreas was identified and classified only recently. IPMT has a primarily intraductal, papillomatous growth pattern, which is associated with excessive mucin secretion and results in progressive ductal dilatation or cyst formation. The tumor occurs in four forms: segmental or diffuse involvement of the main pancreatic duct and macrocystic or microcystic involvement of a branch duct. In the past, many IPMTs may have been misdiagnosed as chronic pancreatitis because of their generally benign behavior. The correct diagnosis, once achieved only with endoscopic retrograde cholangiopancreatography (ERCP), can now be made with noninvasive imaging modalities, particularly computed tomography (CT) and magnetic resonance (MR) imaging. ERCP remains the imaging modality of choice for diagnosis of IPMT. With ERCP, the communication between the cystically dilated ductal segment or branch duct and the main pancreatic duct is easily demonstrated. However, reflux of contrast material due to an excess of mucin or an enlarged papillary orifice hinders filling of the ductal tree. Filling defects due to mucin globs or mural nodules are also important clues to the diagnosis. Bulging of the papilla into the duodenal lumen is virtually pathognomonic of IPMT and is well demonstrated with CT or MR imaging.
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Research Interests: Medicine()
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Scientific Posters LL-BR4082-H0
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Research Interests: Surgery, Medicine, Maternal Mortality, Postpartum Haemorrhage, Prospective studies, and 15 morePregnancy, Humans, Neuroradiology, Female, Interventional Radiology, Hysterectomy, Angiography, Adult, Blood Transfusion, Bleeding, Postpartum Hemorrhage, Contrast Media, Maternal Morbidity, Laparotomy, and postpartum period
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Research Interests: Radiology, Magnetic Resonance Imaging, Pancreatitis, Medicine, Abdominal Imaging, and 12 moreHumans, Pancreas, Magnetic Resonance, Chronic Pancreatitis, Clinical Sciences, Papillary Squamous Cell Carcinoma, High Resolution, Spatial resolution, Magnetic Resonance Cholangiopancreatography, Abdominal, Cholangiopancreatography, and MRCP
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To determine the radiologic characteristics of cystic dystrophy of the duodenal wall. Ten patients with cystic dystrophy of the duodenal wall and chronic pancreatitis underwent ultrasonography (US) (n = 10), computed tomography (CT) (n =... more
To determine the radiologic characteristics of cystic dystrophy of the duodenal wall. Ten patients with cystic dystrophy of the duodenal wall and chronic pancreatitis underwent ultrasonography (US) (n = 10), computed tomography (CT) (n = 10), endoscopic US (n = 5), and endoscopic retrograde cholangiopancreatography (ERCP) (n = 9). Cystic dystrophy of the duodenal wall was classified as either cystic or solid. The imaging findings were retrospectively analyzed and compared with findings at pancreatoduodenectomy (n = 10). The more frequent cystic type (n = 7) of cystic dystrophy of the duodenal wall was characterized by the presence of easily recognizable cystic lesions (diameter, more than 1 cm), located within the thickened wall of the second portion of the duodenum. The solid type (n = 3) of cystic dystrophy of the duodenal wall demonstrated fibrous thickening of the duodenal wall within which small cysts (diameter, less than 1 cm) were present. The intraduodenal cysts were usually elongated or bilobate with a thick wall. The thickening of the duodenal wall appeared as a solid layer between the duodenal lumen and the pancreas, hypoechoic at US, isoattenuating at unenhanced CT, and hypoattenuating in the early phase (after initiation of infusion of contrast material) and isoattenuating in the late phase (after completion of infusion) at contrast material-enhanced CT. Findings at retrospective analysis of CT and endoscopic US images were characteristic. Imaging modalities, notably CT and endoscopic US, helped establish the diagnosis of cystic dystrophy of the duodenal wall.
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Research Interests: Radiology, Computed Tomography, Magnetic Resonance Imaging, Medicine, Hepatology, and 15 moreAbdominal Imaging, Humans, Internal Medicine, Female, Male, Magnetic Resonance, Differential Diagnosis, Clinical Sciences, Aged, Middle Aged, Cross Section, Cross sectional Study, Image Features, Malignancy, and Pancreatic neoplasms
Page 1. In this chapter, both the macro-and microscopic pathological aspect of pancreatic tumors and tumor-like conditions are reviewed, and particular focus is giv-en to those features that affect the findings at ultra-sound ...
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To assess the utility of second-look ultrasound (US) for identifying and characterising incidental enhancing lesions detected by breast magnetic resonance imaging (MRI). From among 655 consecutive breast MRI studies, 62 lesions (MRI... more
To assess the utility of second-look ultrasound (US) for identifying and characterising incidental enhancing lesions detected by breast magnetic resonance imaging (MRI). From among 655 consecutive breast MRI studies, 62 lesions (MRI visible, nonpalpable, occult at first-look US and mammography) were recommended for second-look US. MRI enhancement of lesions was mass-like in 59 cases (95%) and non-mass-like in three (5%). Forty-two lesions (68%) were ≤10 mm; only three lesions (5%) were &amp;amp;gt;20 mm. Of all lesions, the Breast Imaging Reporting and Data System (BI-RADS) MRI category was highly suggestive of malignancy in six cases (10%), suspicious abnormality in 33 (53%) and probably benign in 23 (37%). The correlation between MRI lesion appearance, lesion size, histopathology findings and detection rate at second-look US were analysed. The reference standard was histopathology and/or follow-up (range 18-24 months). Statistical analysis was performed with the Fisher exact test. Second-look US identified 44 out of 62 (71%) lesions depicted at MRI. The detection rate at second-look US was higher for mass-like MRI lesions (75%) than non-mass-like lesions (0%), for lesion size &amp;amp;gt;10mm (90%) and for BI-RADS 4 lesions (88%). Second-look US-guided biopsy detected 12 out of 17 (71%) malignant lesions. There was no correlation between the likelihood of carcinoma and the presence of a sonographic correlate. Second-look US is a reliable problem-solving tool in identifying and characterising most incidental MRI findings. It contributes to accurately selecting the cases in which MRI-guided biopsy is required.
Research Interests: Computer Science, Magnetic Resonance Imaging, Biopsy, Humans, Histopathology, and 15 moreFemale, Breast MRI, Breast Imaging, Incidental Findings, Differential Diagnosis, Breast, Mammography, Aged, Adult, Lesion, Detection Rate, Contrast Media, Magnetic resonance image, Malignancy, and Breast Neoplasms
poste
Research Interests: Radiology, Magnetic Resonance Imaging, MRI, Medicine, Pancreas, and 3 moreCEUS, Electronic Commerce, and MRCP
This study was done to verify the usefulness of preoperative breast magnetic resonance (MR) imaging in patients with newly diagnosed breast cancer. A retrospective analysis of 291 patients with invasive breast cancer newly diagnosed with... more
This study was done to verify the usefulness of preoperative breast magnetic resonance (MR) imaging in patients with newly diagnosed breast cancer. A retrospective analysis of 291 patients with invasive breast cancer newly diagnosed with conventional breast imaging (mammography and ultrasound) was performed. All patients underwent MR imaging prior to surgery. The MR imaging detection rate of additional malignant cancers occult to mammography and ultrasound was calculated. Data were analysed with Fisher&amp;amp;#39;s exact test (p&amp;amp;lt;0.05) according to the following parameters: histopathological features of the index tumour (histological type and size) and mammographic density [according to the Breast Imaging Reporting and Data System (BI-RADS) classification from 1 fatty to 4 dense). The gold standard was the histological examination on the surgical specimen. MR imaging identified 40 mammographically and sonographically occult malignant lesions other than the index cancer in 27/291 patients (9%). These additional cancers were located in the same quadrant as the index cancer in 13 women (4%), in a different quadrant in 12 (4%) and in the contralateral breast in the remaining two (1%). The cancer detection rate in the subgroup of index cancers with lobular histological type was 25%, significantly higher (p=0.03) than the detection rate of 11% recorded in the subgroup of ductal cancers. The cancer detection rate in the subgroup of index cancers &amp;amp;gt;2 cm was 27%, significantly higher (p=0.001) than the rate of 8% found in the subgroup of index cancers &amp;amp;lt;2 cm. Mammographic density was not correlated (p=0.48) with MR detection of additional cancer, with 14% of additional malignancies being detected in both dense and fatty breasts. In patients with newly diagnosed invasive breast cancer, preoperative MR imaging is useful for detecting additional synchronous malignancies that are not detected on conventional breast imaging. The cancer detection rate is 9%. The use of preoperative MR imaging as an adjunct to conventional breast imaging in women with an infiltrating lobular index cancer and an index cancer &amp;amp;gt;2 cm is especially beneficial.
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Research Interests: Computed Tomography, Magnetic Resonance Imaging, Medicine, Hepatology, Abdominal Imaging, and 15 moreHumans, Pancreas, Female, Male, Clinical Sciences, Aged, Cross Section, Endoscopic Retrograde Cholangiopancreatography, Adenocarcinoma, Pancreatic Cyst, Image Features, Magnetic Resonance Cholangiopancreatography, Magnetic resonance image, cystadenocarcinoma, and Cystadenoma
The purpose of this work was to evaluate the capabilities of CT to accurately characterize cystic tumors of the pancreas. Two observers retrospectively evaluated the CT exams of 100 cystic masses of the pancreas, with pathological... more
The purpose of this work was to evaluate the capabilities of CT to accurately characterize cystic tumors of the pancreas. Two observers retrospectively evaluated the CT exams of 100 cystic masses of the pancreas, with pathological confirmation. The two observers, blinded about clinical information and the final diagnosis, tried to categorize the lesions according to well established morphologic features. Statistical analysis was performed to measure the agreement between each radiologist and the consensus diagnosis and to evaluate the usefulness of certain CT findings in differentiating one type of cystic pancreatic neoplasm from another. Serous cystadenoma was better diagnosed by CT [Youden misclassification index (Ymi) = 0.72] than mucinous cystic tumor (Ymi = 0.44) and solid pseudopapillary tumor (cystic variant) (Ymi = 0.47). As patients with previous history of pancreatitis were excluded from the study, CT findings allowed correct characterization of only 60% of cystic pancreatic masses. Among the remaining 40%, 15-20% of the wrong diagnoses could not be corrected by means of CT, given the patterns shown by the tumors. In 20-25% of the cases, a nonspecific diagnosis of cystic mass was made.
Research Interests: Radiology, Medicine, Humans, Pancreas, Differential Diagnosis, and 14 moreClinical Sciences, Medical Diagnosis, Computer Assisted Tomography, Retrospective Studies, Lymphangioma, Sensitivity and Specificity, X ray Computed Tomography, Computer, Neuroendocrine Tumors, Contrast Media, Pancreatic Cyst, SEROUS CYSTADENOMA, Cystadenoma, and Pancreatic neoplasms
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Research Interests: Algorithms, Radiology, Magnetic Resonance Imaging, Nuclear medicine, Medicine, and 15 moreProspective studies, Humans, Female, Male, Bone marrow, ROC Curve, Clinical Sciences, Middle Aged, Adult, Sensitivity and Specificity, X ray Computed Tomography, Ankle, Predictive value of tests, Ankle injuries, and Medical and Health Sciences
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Poster: "ECR 2017 / C-2866 / PI-RADS v2 for predicting prostate cancer Gleason score at final pathology after radical prostatectomy" by: "E. Demozzi, G. Foti, L. Romano, F. M. Cavicchioli, A. Molinari, S. Cavalleri, G.... more
Poster: "ECR 2017 / C-2866 / PI-RADS v2 for predicting prostate cancer Gleason score at final pathology after radical prostatectomy" by: "E. Demozzi, G. Foti, L. Romano, F. M. Cavicchioli, A. Molinari, S. Cavalleri, G. Carbognin; Negrar/IT"
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Poster: "ECR 2013 / C-0632 / Understimation rate in ultrasound detected lesions using vacuum assisted device: correlation to surgical excision" by: "V. Girardi1, G. Carbognin2, A. Barni2, P. Chiodera2; 1Peschiera del... more
Poster: "ECR 2013 / C-0632 / Understimation rate in ultrasound detected lesions using vacuum assisted device: correlation to surgical excision" by: "V. Girardi1, G. Carbognin2, A. Barni2, P. Chiodera2; 1Peschiera del Garda/IT, 2Brescia/IT"