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A 17-year-old boy came to our hospital with a wound infection 5 days after urological surgery. CT scan done to assess the depth of the infection showed multiple well circumscribed, ovoid, radiodense bony lesions in the pelvis and proximal... more
A 17-year-old boy came to our hospital with a wound infection 5 days after urological surgery. CT scan done to assess the depth of the infection showed multiple well circumscribed, ovoid, radiodense bony lesions in the pelvis and proximal femurs, consistent with the diagnosis of osteopoikilosis. Osteopoikilosis or "spotted bone disease" is a rare, benign, autosomal dominant disorder charac terised by sclerotic bone lesions most commonly involving the hands, feet, pelvis, and ends of long bones. 1,2 Lesions are typically found incidentally on imaging studies done for unrelated complaints. 3 The symmetric distribution, lack of bone destruction, and location diff erentiates osteopoikilosis from metastatic disease, which tends to be seen more often in ribs, vertebral bodies, and the diaphysis of long bones. 4 Bone scintigraphy is normal in patients with osteopoikilosis. 2,4 Early recognition is essential to prevent unnecessary emotional distress and invasive testing. 3 No rout...
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l7-year-old male with Crohn disease presented with a history of abdominal pain for 2 days and a diffuse, scaly rash for 2 weeks. Physical examination revealed lower abdominal tenderness and right hip pain with flexion. Coarse skin with... more
l7-year-old male with Crohn disease presented with a history of abdominal pain for 2 days and a diffuse, scaly rash for 2 weeks. Physical examination revealed lower abdominal tenderness and right hip pain with flexion. Coarse skin with hyperpigmented, rectangular lesions in horizontal arrays was distributed over his trunk, buttocks, and lower ex-tremities (A). Computed tomography scans of the abdomen and pelvis showed an iliopsoas abscess (B), which was drained percutane-ously. Gastrointesdnal and cutaneous manifestations resolved 2 months after initiadon of infliximab therapy. Acquired ichthyosis (AI) is characterized by symmetric, dry skin with platelilie scales distributed over the trunk and limbs.l The condition is asvrnptomatic other than mild pruritus and is more prominenr or-er the lower extremities.2 On histologic examination, hrperkeratosis and the lack of a granular layer are seen.r AI is associated with autoimmune disease, hypothy-roidism, malignano-. sarcoidosis, Iiver d...
l7-year-old male with Crohn disease presented with a history of abdominal pain for 2 days and a diffuse, scaly rash for 2 weeks. Physical examination revealed lower abdominal tenderness and right hip pain with flexion. Coarse skin with... more
l7-year-old male with Crohn disease presented with a history of abdominal pain for 2 days and a diffuse, scaly rash for 2 weeks. Physical examination revealed lower abdominal tenderness and right hip pain with flexion. Coarse skin with hyperpigmented, rectangular lesions in horizontal arrays was distributed over his trunk, buttocks, and lower ex-tremities (A). Computed tomography scans of the abdomen and pelvis showed an iliopsoas abscess (B), which was drained percutane-ously. Gastrointesdnal and cutaneous manifestations resolved 2 months after initiadon of infliximab therapy. Acquired ichthyosis (AI) is characterized by symmetric, dry skin with platelilie scales distributed over the trunk and limbs.l The condition is asvrnptomatic other than mild pruritus and is more prominenr or-er the lower extremities.2 On histologic examination, hrperkeratosis and the lack of a granular layer are seen.r AI is associated with autoimmune disease, hypothy-roidism, malignano-. sarcoidosis, Iiver d...