Vincenzo Amico
Università di Catania, Dipartimento di scienze chimiche, Faculty Member
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Publication Date: 1974
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by Corrado Tringali and Vincenzo Amico
Publication Date: 1976
Publication Name: Biochemical Systematics and Ecology
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Grape stems from Sicilian Vitis vinifera cultivars as a source of polyphenol-enriched fractions with enhanced antioxidant activitymore
by Corrado Tringali and Vincenzo Amico
ABSTRACT From a screening of six different samples of grape stems from Vitis vinifera Sicilian cultivars, ‘Nerello Mascalese’ as well as ‘Nero d’Avola’ ethanol extracts showed promising radical scavenging activity and phenol content... more
ABSTRACT From a screening of six different samples of grape stems from Vitis vinifera Sicilian cultivars, ‘Nerello Mascalese’ as well as ‘Nero d’Avola’ ethanol extracts showed promising radical scavenging activity and phenol content (DPPH� and GAE assays). Aliquots of these three extracts were subjected to two different fractionation protocols on polyamide (PF) and Amberlite XAD-16 (XF). The fractions were examined by DPPH� and GAE assays, and subjected to HPLC-DAD analysis for the quantitative determination of the main phenolic compounds. Fractionation of the crude extract NM1E (SC50 = 28.2, GAE = 221.0) through the XF protocol, afforded a polyphenol-enriched fraction (XF1C, GAE = 392.5) with highly enhanced antioxidant activity (SC50 = 7.0), and accounting for only 6.5% in weight of the NM1E extract. Fraction XF1C shows high concentrations of a procyanidin B1 (Pcd) and catechin (Cat). Some considerations on the relationship between antioxidant activity and phenolic HPLC-DAD profiles are also reported.
Publication Date: 2013
Publication Name: LWT - Food Science and Technology
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The fractionation, guided by cell-growth inhibition assay, of the EtOAc crude extract from grape stems of the Sicilian Vitis vinifera variety 'Nerello Mascalese' allowed identification often constituents, isolated either as pure... more
The fractionation, guided by cell-growth inhibition assay, of the EtOAc crude extract from grape stems of the Sicilian Vitis vinifera variety 'Nerello Mascalese' allowed identification often constituents, isolated either as pure compounds (1, 3-5, 7-10) or inseparable mixtures (2a-d and 6a-e). The pure constituents were: two triterpenoid acids, oleanolic (1) and betulinic acids (5); daucosterol (7); a stilbenoid, E-resveratrol (3) and its dimer E-epsilon-viniferin (4); the simple phenol gallic acid (8); and the flavanols catechin (9) and gallocatechin (10). Four 6'-O-acyldaucosterols (2a-d) and five 1,2-di-O-acyl-3-O-beta-D-galactopyranosyl glycerols (6a-e) were also identified as inseparable mixtures. All the isolated compounds were subjected to spectroscopic analysis and MTT bioassay on MCF-7 human breast cancer cells. The majority showed growth-inhibitory activity, 5 being the most active (GI50 = 0.57 microM). Compounds 3-5 were also tested on HT-29, U-87-MG and U-373...
Publication Date: 2009
Publication Name: Natural product communications
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by Corrado Tringali and Vincenzo Amico
... Abbott, OJ Perkins, EJ (1977). ... Concentrations of PCBs, BHCs and DDTs Residues in Seaweeds of the East Coast of Sicily VINCENZO AMICO, GIOVANNA ORIENTE, MARIO PIATTELLI andCORRADO TRINGALI Istituto Dipartimentale di Chimica a... more
... Abbott, OJ Perkins, EJ (1977). ... Concentrations of PCBs, BHCs and DDTs Residues in Seaweeds of the East Coast of Sicily VINCENZO AMICO, GIOVANNA ORIENTE, MARIO PIATTELLI andCORRADO TRINGALI Istituto Dipartimentale di Chimica a Chimica Industriale dell ...
Publication Date: 1979
Publication Name: Marine Pollution Bulletin
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by Corrado Tringali and Vincenzo Amico
... FROM THE BROWN ALGA ZONARIA TOURNEFORTII VINCENZO AMIGO, GIOVANNI NICOLOSI, GIOVANNA ORIENTE, MARIO PIATTELLI and CORRADO TRINGALI Istituto Dipartimentale di Chimica dell'Universita di Catania, V. le A. Doria, Catania, Italy... more
... FROM THE BROWN ALGA ZONARIA TOURNEFORTII VINCENZO AMIGO, GIOVANNI NICOLOSI, GIOVANNA ORIENTE, MARIO PIATTELLI and CORRADO TRINGALI Istituto Dipartimentale di Chimica dell'Universita di Catania, V. le A. Doria, Catania, Italy (Received 22 June ...
Publication Date: 1982
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Isolation of (2R, 8R)-germacra-1 (11), 5 (12), E6-trien-2-ol acetate from the brown alga dilophusfasciolamore
by Corrado Tringali and Vincenzo Amico
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by Corrado Tringali and Vincenzo Amico
Publication Date: 1976
Publication Name: Journal of the Chemical Society, Chemical Communications
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by Corrado Tringali and Vincenzo Amico
Publisher: Elsevier
Publication Date: 1978
Publication Name: Tetrahedron Letters
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by Corrado Tringali and Vincenzo Amico
Publication Date: 1979
Publication Name: Phytochemistry
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by Corrado Tringali and Vincenzo Amico
Publication Date: 1976
Publication Name: Tetrahedron Letters
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by Corrado Tringali and Vincenzo Amico
Publication Date: 1980
Publication Name: Tetrahedron
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Publication Date: 1981
Publication Name: Phytochemistry
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ABSTRACT
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Publication Date: 1980
Publication Name: Phytochemistry
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Publication Date: 1982
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... and K.2.2.2. Angelo Lunghi ", Paolo Cardillo a, Teresa Messina b, Pierangelo Metrangolo b, Walter Panzeri b, Giuseppe Resnati b,, "Stazione sperimentale combustibili, via De Gasperi 3, 20097 San Donato Milanese, Milan, Italy... more
... and K.2.2.2. Angelo Lunghi ", Paolo Cardillo a, Teresa Messina b, Pierangelo Metrangolo b, Walter Panzeri b, Giuseppe Resnati b,, "Stazione sperimentale combustibili, via De Gasperi 3, 20097 San Donato Milanese, Milan, Italy b ... [ 16] JR McDivitt, GL Humphrey, Spectrochim. ...
Publication Date: 1998
Publication Name: Journal of the American Chemical Society
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by Vincenzo Amico and Corrado Tringali
Publication Date: 1977
Publication Name: Journal of Chromatography A
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by Corrado Tringali and Vincenzo Amico
The quantitative gas--liquid chromatographic analysis of non-protein amino acids, in the presence of protein amino acids, is described. The amino acids were determined as their N-trifluoroacetyl n-butyl esters on an ethylene glycol... more
The quantitative gas--liquid chromatographic analysis of non-protein amino acids, in the presence of protein amino acids, is described. The amino acids were determined as their N-trifluoroacetyl n-butyl esters on an ethylene glycol adipate column. The relative molar responses of 38 amino acids are reported.
Publication Date: 1976
Publication Name: Journal of Chromatography A
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Antiproliferative Terpenoids from Almond Hulls ( Prunus dulcis ): Identification and Structure−Activity Relationshipsmore
by Corrado Tringali and Vincenzo Amico
Bioassay-guided fractionation of the EtOAc crude extract from Sicilian almond hulls, a waste material from Prunus dulcis crop, allowed identification of 10 constituents, isolated as pure compounds (1-5, 7, and 10) or unseparable mixtures... more
Bioassay-guided fractionation of the EtOAc crude extract from Sicilian almond hulls, a waste material from Prunus dulcis crop, allowed identification of 10 constituents, isolated as pure compounds (1-5, 7, and 10) or unseparable mixtures (5 + 6 and 8 + 9). All compounds were subjected to spectroscopic analysis and 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide bioassay on MCF-7 human breast cancer cells. In addition to the main components oleanolic (1), ursolic (2), and betulinic (3) acids, the 2-hydroxy analogues alphitolic (4), corosolic (5), and maslinic (6) acids, as well as the related aldehydes, namely, betulinic (7), oleanolic (8), and ursolic (9), were identified. From a more polar fraction, the beta-sitosterol 3-O-glucoside (10) was also identified. A sample of commercially available betulin (11) was also included in bioassays as further support to a structure-activity relationship study. Betulinic acid showed antiproliferative activity toward MCF-7 cells (GI50 = 0.27 microM), higher than the anticancer drug 5-fluorouracil.
Publication Date: 2006
Publication Name: Journal of Agricultural and Food Chemistry
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The methanolic extracts (MeOH) obtained from de-stemmed grape pomace samples of five Sicilian red grape cultivars (Nero d′Avola-NA, Nerello Mascalese-NM, Nerello Cappuccio-NC, Frappato-FR and Cabernet Sauvignon-CS) were evaluated for... more
The methanolic extracts (MeOH) obtained from de-stemmed grape pomace samples of five Sicilian red grape cultivars (Nero d′Avola-NA, Nerello Mascalese-NM, Nerello Cappuccio-NC, Frappato-FR and Cabernet Sauvignon-CS) were evaluated for their DPPH and ABTS− radical scavenging capacity, and submitted to HPLC–UV–DAD and HPLC–MS–ESI analysis to determine the main polyphenolic constituents, namely anthocyanins and flavonols. All the MeOH extracts showed significant antioxidant activity, with some differences between the two methods employed. The NM sample was the most active in both tests. A large variability in the total anthocyanin (TA) and flavonol (TF) contents of the MeOH extracts, as well as in the quantitative distribution of the single anthocyanins and flavonols was observed. Statistically insignificant correlations between the TA+TF content and antioxidant activity, as measured by DPPH and ABTS− model systems (r2=0.0607, P>0.05; r2=0.3471, P>0.05), were established, but the most active sample, NM, showed the highest content of anthocyanins including a free catechol moiety in their structure.
Publication Date: 2007
Publication Name: Food Chemistry
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Publication Date: 2004
Publication Name: Food Chemistry
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by Corrado Tringali and Vincenzo Amico
Publication Date: 1979
Publication Name: Experientia
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by Corrado Tringali and Vincenzo Amico
Publication Date: 1977
Publication Name: Experientia
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Publication Date: 1977
Publication Name: Experientia
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The volatile components of grape pomace coming from the processing of some of the most important varieties of grape (Vitis vinifera L.) cultivated in Sicily, namely Nero... more
The volatile components of grape pomace coming from the processing of some of the most important varieties of grape (Vitis vinifera L.) cultivated in Sicily, namely Nero d'Avola, Nerello Mascalese, Frappato and Cabernet Sauvignon, have been determined by gas-chromatography (GC) and gas-chromatography-mass spectrometry (GC-MS). According to the winemaking procedure that entails the removal of stalks before fermentation, two kinds of grape pomace are obtained. The first consists of skins, pulp residues and seeds, the proper grape pomace, which is partially used for grappa, a typical Italian spirit, and alcohol production, the second consists almost exclusively of stalks. On the whole, 38 components have been characterized in the samples of grape pomaces, with Frappato cv. showing the richest composition; instead, 88 components have been detected in the stalks of Frappato, Nero d'Avola, Nerello Mascalese and Cabernet Sauvignon varieties. In order to make a comparison between the grape varieties easier, the volatile components detected in the two sets of samples (grape pomaces and stalks) have been grouped in different classes. Significant differences among varieties have been detected and statistical treatment of data is also reported. This study is part of a wider project aimed at the possible exploitation of the main agro-industrial by-products. At the same time it is one of the first reports on the volatile components of this waste material.
Publication Date: 2008
Publication Name: Bioresource Technology
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Polyphenol-enriched fractions from Sicilian grape pomace: HPLC–DAD analysis and antioxidant activitymore
by Corrado Tringali and Vincenzo Amico
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