Periconceptional maternal micronutrient supplementation is associated with widespread gender related changes in the epigenome: a study of a unique resource in …
B Khulan, WN Cooper, BM Skinner… - Human molecular …, 2012 - academic.oup.com
In addition to the genetic constitution inherited by an organism, the developmental trajectory
and resulting mature phenotype are also determined by mechanisms acting during critical …
and resulting mature phenotype are also determined by mechanisms acting during critical …
[HTML][HTML] Effect of maternal preconceptional and pregnancy micronutrient interventions on children's DNA methylation: Findings from the EMPHASIS study
Background Maternal nutrition in pregnancy has been linked to offspring health in early and
later life, with changes to DNA methylation (DNAm) proposed as a mediating mechanism …
later life, with changes to DNA methylation (DNAm) proposed as a mediating mechanism …
DNA methylation profiling at imprinted loci after periconceptional micronutrient supplementation in humans: results of a pilot randomized controlled trial
Intrauterine exposures mediated by maternal diet may affect risk of cardiovascular disease,
obesity, and type 2 diabetes. Recent evidence, primarily from animal studies and …
obesity, and type 2 diabetes. Recent evidence, primarily from animal studies and …
Nutrition during pregnancy impacts offspring's epigenetic status—evidence from human and animal studies
AA Geraghty, KL Lindsay, G Alberdi… - Nutrition and …, 2015 - journals.sagepub.com
Pregnancy is a vital time of growth and development during which maternal nutrition
significantly influences the future health of both mother and baby. During pregnancy, the …
significantly influences the future health of both mother and baby. During pregnancy, the …
Season of conception in rural gambia affects DNA methylation at putative human metastable epialleles
RA Waterland, R Kellermayer, E Laritsky… - PLoS …, 2010 - journals.plos.org
Throughout most of the mammalian genome, genetically regulated developmental
programming establishes diverse yet predictable epigenetic states across differentiated cells …
programming establishes diverse yet predictable epigenetic states across differentiated cells …
Early gestation as the critical time-window for changes in the prenatal environment to affect the adult human blood methylome
Background: The manipulation of pregnancy diets in animals can lead to changes in DNA
methylation with phenotypic consequences in the offspring. Human studies have …
methylation with phenotypic consequences in the offspring. Human studies have …
Ancestry dependent DNA methylation and influence of maternal nutrition
There is extensive variation in DNA methylation between individuals and ethnic groups.
These differences arise from a combination of genetic and non-genetic influences and …
These differences arise from a combination of genetic and non-genetic influences and …
The effects of maternal and postnatal dietary methyl nutrients on epigenetic changes that lead to non-communicable diseases in adulthood
RS Randunu, RF Bertolo - International journal of molecular sciences, 2020 - mdpi.com
The risk for non-communicable diseases in adulthood can be programmed by early nutrition.
This programming is mediated by changes in expression of key genes in various metabolic …
This programming is mediated by changes in expression of key genes in various metabolic …
Early nutrition: impact on epigenetics
JC Mathers - Nutrigenomics-Opportunities in Asia, 2007 - karger.com
Background/Aims:(1) To outline the findings that alterations in nutrition in utero and in early
postnatal life influence health in later life.(2) To review the evidence that alterations in …
postnatal life influence health in later life.(2) To review the evidence that alterations in …
Maternal nutrition at conception modulates DNA methylation of human metastable epialleles
P Dominguez-Salas, SE Moore, MS Baker… - Nature …, 2014 - nature.com
In experimental animals, maternal diet during the periconceptional period influences the
establishment of DNA methylation at metastable epialleles in the offspring, with permanent …
establishment of DNA methylation at metastable epialleles in the offspring, with permanent …