Cellular determinants involving mitochondrial dysfunction, oxidative stress and apoptosis correlate with the synergic cytotoxicity of epigallocatechin-3-gallate and …
We have investigated the growth-suppressive action of epigallocatechin-3-gallate (EGCG)
on human leukemia Jurkat T cells. Results show a strong correlation between the dose …
on human leukemia Jurkat T cells. Results show a strong correlation between the dose …
Induction of apoptosis by epigallocatechin-3-gallate in human lymphoblastoid B cells
C Noda, J He, T Takano, C Tanaka, T Kondo… - Biochemical and …, 2007 - Elsevier
(−)-Epigallocatechin-3-gallate (EGCG), a major constituent of green tea polyphenols, has
been shown to suppress cancer cell proliferation and induce apoptosis. In this study we …
been shown to suppress cancer cell proliferation and induce apoptosis. In this study we …
[HTML][HTML] Negative modulation of mitochondrial oxidative phosphorylation by epigallocatechin-3 gallate leads to growth arrest and apoptosis in human malignant …
Increasing evidence reveals a large dependency of epithelial cancer cells on oxidative
phosphorylation (OXPHOS) for energy production. In this study we tested the potential of …
phosphorylation (OXPHOS) for energy production. In this study we tested the potential of …
Epigallocatechin-3-gallate-induced stress signals in HT-29 human colon adenocarcinoma cells
C Chen, G Shen, V Hebbar, R Hu, ED Owuor… - …, 2003 - academic.oup.com
Abstract Epigallocatechin-3-gallate (EGCG), a major component in green tea polyphenols,
has been proven to suppress colonic tumorigenesis in animal models and epidemiological …
has been proven to suppress colonic tumorigenesis in animal models and epidemiological …
Catechin, a green tea component, rapidly induces apoptosis of myeloid leukemic cells via modulation of reactive oxygen species production in vitro and inhibits tumor …
T Nakazato, K Ito, Y Miyakawa, K Kinjo… - …, 2005 - haematologica.org
BACKGROUND AND OBJECTIVES: The aim of this study was to investigate the possibility of
green tea polyphenol,(-)-epigallocatechin-3-gallate (EGCG) as a novel therapeutic agent for …
green tea polyphenol,(-)-epigallocatechin-3-gallate (EGCG) as a novel therapeutic agent for …
Difference in growth suppression and apoptosis induction of EGCG and EGC on human promyelocytic leukemia HL-60 cells
DH Han, JH Kim - Archives of pharmacal research, 2009 - Springer
Growth suppression and apoptosis inducing effect of (−)-epigallocatechin 3-gallate (EGCG)
and (−)-epigallocatechin (EGC) were studied against human promyeolcytic leukemia, HL-60 …
and (−)-epigallocatechin (EGC) were studied against human promyeolcytic leukemia, HL-60 …
Inhibition of proliferation and induction of apoptosis by EGCG in human osteogenic sarcoma (HOS) cells
SJ Ji, DH Han, JH Kim - Archives of pharmacal research, 2006 - Springer
Abstract EGCG [(−)-epigallocatechin-3-gallate], a major component of green tea has been
considered as a major antioxidant constituent. In addition to having been considered for …
considered as a major antioxidant constituent. In addition to having been considered for …
(−)‐Epigallocatechin‐3‐gallate induces cell apoptosis in chronic myeloid leukaemia by regulating Bcr/Abl‐mediated p38‐MAPK/JNK and JAK 2/STAT 3/AKT …
X Xiao, K Jiang, Y Xu, H Peng, Z Wang… - Clinical and …, 2019 - Wiley Online Library
Summary Epigallocatechin‐3‐gallate (EGCG), a major polyphenolic constituent of green
tea, possesses remarkable chemopreventive and therapeutic potential against various types …
tea, possesses remarkable chemopreventive and therapeutic potential against various types …
In Vitro Toxicity of Epigallocatechin Gallate in Rat Liver Mitochondria and Hepatocytes
O Kucera, V Mezera, A Moravcova… - Oxidative medicine …, 2015 - Wiley Online Library
Epigallocatechin‐3‐gallate (EGCG) is the main compound of green tea with well‐described
antioxidant, anti‐inflammatory, and tumor‐suppressing properties. However, EGCG at high …
antioxidant, anti‐inflammatory, and tumor‐suppressing properties. However, EGCG at high …
(−)-Epigallocatechin-3-gallate potentiates the cytotoxicity induced by benzyl isothiocyanate and hydrogen peroxide in human Jurkat T lymphocytes
H Wu, T Yokoyama, B Zhu, Y Shimoishi… - Bioscience …, 2008 - Taylor & Francis
(−)-Epigallocatechin-3-gallate (EGCG)-induced apoptosis was along both the extracellular
signal-regulated protein kinase (ERK) and c-jun N-terminal kinase (JNK) pathways in Jurkat …
signal-regulated protein kinase (ERK) and c-jun N-terminal kinase (JNK) pathways in Jurkat …
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