The resolution limit of chromatin conformation capture methodologies (3Cs) has restrained
their application in detection of fine-level chromatin structure mediated by cis-regulatory …

Here we present Tri-4C, a targeted chromatin conformation capture method for ultrafine
mapping of chromatin interactions. Tri-4C quantitatively reveals cis-regulatory loops with …

Genome organization is now understood to be tightly linked to all genomic functions. Thus,
the high-resolution mapping of higher-order chromosomal structures via 3C-based …

The regulation of cell-type-specific transcription programs is a highly controlled and complex
process that needs to be fully understood. The gene regulation is often influenced by distal …

The 3D organization of the genome facilitates gene regulation, replication, and repair,
making it a key feature of genomic function and one that remains to be properly understood …

Abstract Micro Capture-C (MCC) is a chromatin conformation capture (3C) method for
visualizing reproducible three-dimensional contacts of specified regions of the genome at …

Chromosome conformation capture and its variants interrogate population-average
chromatin structure at a higher resolution and throughput than microscopic methods …

Chromosome conformation capture (3C) provides an adaptable tool for studying diverse
biological questions. Current 3C methods generally provide either low-resolution interaction …

Chromatin architecture, a key regulator of gene expression, can be inferred using chromatin
contact data from chromosome conformation capture, or Hi-C. However, classical Hi-C does …

Promoter-focused chromatin conformation techniques directly detect interactions between
gene promoters and distal genomic sequences, providing structural information relevant to …