Antioxidant therapy in inflammatory bowel diseases

K Dziąbowska-Grabias, M Sztanke, P Zając… - Antioxidants, 2021 - mdpi.com
… , incurable diseases of the digestive tract, the etiology of … to diverse, potentially detrimental
side effects and frequently do not … Relative to this, several substances with antioxidant and anti-…

Biochemistry of antioxidants: Mechanisms and pharmaceutical applications

S Losada-Barreiro, Z Sezgin-Bayindir, F Paiva-Martins… - Biomedicines, 2022 - mdpi.com
… Surfactants commonly used in food and pharmaceutical productsantioxidant that is available
for absorption in the intestine … due to antioxidant activity and increased drug transport to the …

Pharmaceutical formulations with P-glycoprotein inhibitory effect as promising approaches for enhancing oral drug absorption and bioavailability

TTL Nguyen, VA Duong, HJ Maeng - Pharmaceutics, 2021 - mdpi.com
… the critical impact of P-gp inhibitors in enhancing the intestinal … the effects of P-gp inhibitors
in the improvement of intestinal … 4 C, indicating that drug transport was mediated by the carrier …

Dietary flavonoids: Cardioprotective potential with antioxidant effects and their pharmacokinetic, toxicological and therapeutic concerns

J Khan, PK Deb, S Priya, KD Medina, R Devi… - Molecules, 2021 - mdpi.com
… electron transport chain where the generation of ROS takes place due to the leakage of a
small fraction of electrons to oxygen. Antioxidants … Colonic microbiota present in our gut can …

Translational approaches with antioxidant phytochemicals against alcohol-mediated oxidative stress, gut dysbiosis, intestinal barrier dysfunction, and fatty liver …

JW Ballway, BJ Song - Antioxidants, 2021 - mdpi.com
… However, gut dysbiosis and leaky gut can be normalized through lifestyle alterations …
antioxidant phytochemicals. In this review, we describe the mechanisms of gut dysbiosis, leaky gut, …

Pharmaceutical drugs and natural therapeutic products for the treatment of type 2 diabetes mellitus

J Blahova, M Martiniakova, M Babikova, V Kovacova… - Pharmaceuticals, 2021 - mdpi.com
… of action may include a reduced rate of intestinal absorption, … health products is lower than
that of pharmaceutical products [… The antitumor, antioxidant and antidiabetic effects of the fruit …

Transport, metabolism and remedial potential of functional food extracts (FFEs) in Caco-2 cells monolayer: A review

M Iftikhar, A Iftikhar, H Zhang, L Gong… - Food Research …, 2020 - Elsevier
… Caco-2, a human intestinal carcinoma cell line, has been used to … transport mechanism of
functional foods and drugs across the intestinal epithelium in order to study their antioxidant, …

Effect of P-glycoprotein (P-gp) inducers on exposure of P-gp substrates: review of clinical drugdrug interaction studies

M Elmeliegy, M Vourvahis, C Guo, DD Wang - Clinical pharmacokinetics, 2020 - Springer
… co-regulation with other drug transporters and drug metabolizing enzymes are discussed. …
of the interaction and the differential effect of P-gp induction in the intestine, renal tubules, and …

Role of food antioxidants in modulating gut microbial communities: Novel understandings in intestinal oxidative stress damage and their impact on host health

MS Riaz Rajoka, R Thirumdas, HM Mehwish, M Umair… - Antioxidants, 2021 - mdpi.com
… the gut. The present review summarizes the impact of food antioxidants including antioxidant
… the structure as well as function of host gut microbial communities. Several in vitro, animal …

[HTML][HTML] The influence of the gut microbiota on the bioavailability of oral drugs

X Zhang, Y Han, W Huang, M Jin, Z Gao - Acta Pharmaceutica Sinica B, 2021 - Elsevier
drugs by participating in the biotransformation of oral drugs, influencing the drug transport
process and altering some gastrointestinalgut microbiota and the bioavailability of oral drugs, …