| Opportunities and challenges for the computational interpretation of rare variation in clinically important genes G McInnes, AG Sharo, ML Koleske, JEH Brown, M Norstad, AN Adhikari, ... The American Journal of Human Genetics 108 (4), 535-548, 2021 | 49 | 2021 |
| Understanding drug–drug interaction and pharmacogenomic changes in pharmacokinetics for metabolized drugs LZ Benet, CM Bowman, ML Koleske, CL Rinaldi, JK Sodhi Journal of pharmacokinetics and pharmacodynamics 46, 155-163, 2019 | 38 | 2019 |
| Tetrodotoxin-sensitive Navs contribute to early and delayed afterdepolarizations in long QT arrhythmia models M Koleske, I Bonilla, J Thomas, N Zaman, S Baine, BC Knollmann, ... Journal of General Physiology 150 (7), 991-1002, 2018 | 28 | 2018 |
| Deorphaning a solute carrier 22 family member, SLC22A15, through functional genomic studies SW Yee, D Buitrago, A Stecula, HX Ngo, HC Chien, L Zou, ML Koleske, ... FASEB journal: official publication of the Federation of American Societies …, 2020 | 25 | 2020 |
| Drugs in COVID‐19 clinical trials: predicting transporter‐mediated drug‐drug interactions using in vitro assays and real‐world data SW Yee, B Vora, T Oskotsky, L Zou, S Jakobsen, OJ Enogieru, ... Clinical Pharmacology & Therapeutics 110 (1), 108-122, 2021 | 19 | 2021 |
| New and emerging research on solute carrier and ATP binding cassette transporters in drug discovery and development: outlook from the international transporter consortium KM Giacomini, SW Yee, ML Koleske, L Zou, P Matsson, EC Chen, ... Clinical Pharmacology & Therapeutics 112 (3), 540-561, 2022 | 18 | 2022 |
| Tetrodotoxin‐Sensitive Neuronal‐Type Na+ Channels: A Novel and Druggable Target for Prevention of Atrial Fibrillation MA Munger, Y Olğar, ML Koleske, HL Struckman, J Mandrioli, Q Lou, ... Journal of the American Heart Association 9 (11), e015119, 2020 | 13 | 2020 |
| Functional genomics of OCTN2 variants informs protein-specific variant effect predictor for Carnitine Transporter Deficiency ML Koleske, G McInnes, JEH Brown, N Thomas, K Hutchinson, MY Chin, ... Proceedings of the National Academy of Sciences 119 (46), e2210247119, 2022 | 10 | 2022 |
| The full spectrum of OCT1 (SLC22A1) mutations bridges transporter biophysics to drug pharmacogenomics SW Yee, C Macdonald, D Mitrovic, X Zhou, ML Koleske, J Yang, DB Silva, ... bioRxiv, 2023 | 5 | 2023 |
| The effects of genetic mutations and drugs on the activity of the thiamine transporter, SLC19A2 OJ Enogieru, ML Koleske, B Vora, H Ngo, SW Yee, D Chatad, M Sirota, ... The AAPS journal 23, 1-8, 2021 | 4 | 2021 |
| Differential toxicity to murine small and large intestinal epithelium induced by oncology drugs JM Bieber, LE Sanman, X Sun, H Hammerlindl, F Bao, MA Roth, ... Communications biology 5 (1), 99, 2022 | 2 | 2022 |
| Large-scale mutational analysis of transporters in the Solute Carrier Family 22: Applications in rare disease and pharmacogenetics M Koleske University of California, San Francisco, 2022 | 1 | 2022 |
| Opportunities and challenges for interpreting rare variation in clinically important genes G McInnes, AG Sharo, ML Koleske, JEH Brown, M Norstad, AN Adhikari, ... Preprints, 2020 | 1 | 2020 |
| Illuminating the function of the orphan transporter, SLC22A10, in humans and other primates SW Yee, L Ferrández-Peral, P Alentorn-Moron, C Fontsere, M Ceylan, ... Nature Communications 15 (1), 4380, 2024 | | 2024 |
| The full spectrum of SLC22 OCT1 mutations illuminates the bridge between drug transporter biophysics and pharmacogenomics SW Yee, CB Macdonald, D Mitrovic, X Zhou, ML Koleske, J Yang, ... Molecular Cell 84 (10), 1932-1947. e10, 2024 | | 2024 |
| Effect of Antioxidants in Medicinal Products on Intestinal Drug Transporters CP Kulkarni, J Yang, ML Koleske, G Lara, K Alam, A Raw, B Rege, L Zhao, ... Pharmaceutics 16 (5), 647, 2024 | | 2024 |
| Building a Predictive PBPK Model for Human OATP Substrates: a Strategic Framework for Early Evaluation of Clinical Pharmacokinetic Variations Using Pitavastatin as an Example X Liang, ML Koleske, J Yang, Y Lai The AAPS Journal 26 (1), 13, 2024 | | 2024 |
| ORGANIC CATION AND ZWITTERION TRANSPORTERS ML Koleske, X Liang, OJ Enogieru, D Buitrago, KM Giacomini Drug Transporters: Molecular Characterization and Role in Drug Disposition, 9-32, 2022 | | 2022 |
| HIGH-CONTENT IMAGING OF 150 OCTN2 TRANSPORTER VARIANTS REVEALS SUBCELLULAR LOCALIZATION TO BE PREDICTIVE OF FUNCTION. M Koleske, K Giacomini CLINICAL PHARMACOLOGY & THERAPEUTICS 111, S28-S28, 2022 | | 2022 |
| FUNCTIONAL AND MECHANISTIC CHARACTERIZATION OF NOVEL GENETIC VARIANTS IN THE CARNITINE TRANSPORTER, OCTN2, IDENTIFIED IN NEWBORN SCREENING. M Koleske, K Giacomini CLINICAL PHARMACOLOGY & THERAPEUTICS 109, S25-S25, 2021 | | 2021 |
