[en] How can the implementation of technologies derived from the Fourth Industrial Revolution be carried out in the field of metrology? What strategies can be employed to promote a new infrastructure for digital legal metrology, utilizing cloud computing resources to support compliance evaluation processes? How can we establish parameters for metrological validation in digital simulations of physical phenomena? To address these and other emerging challenges related to the digital revolution in metrology, various global projects have been conceived. This thesis aims to contribute to the resolution of these new challenges, focusing on the development of a conceptual model and application software for quality management and Calibration 4.0 applicable to ionizing radiation metrology. To achieve these objectives, an in-depth state-of-the-art study was conducted, including detailed mappings of the processes involved and the associated calibration risks. Furthermore, software specifically modeled and validated for use in ionizing radiation calibrations was developed. Among the main results achieved are the elaboration of conceptual models that address the impacts of Fourth Industrial Revolution technologies on ionizing radiation metrology and the creation of the Pandora IRTech software, which employs 4.0 technologies for management and calibration purposes. ln summary, the integration of conceptual models with software in laboratory quality management and calibration practices has resulted in a technologically advanced approach that has optimized metrological processes, increased operational efficiency, improved service compliance, and culminated in the issuance of the first digital calibration certificate model in the field of ionizing radiation metrology in Brazil. (author)