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Is there evidence in the EEG for increased epileptiform activity in ICD-10 acute and transient psychotic disorder?more
by Frank Pillmann and Raffaela Blöink
The aim of this study was to examine whether there is electroencephalographic evidence for an increased epileptiform activity in the EEG of ICD-10 acute and transient psychotic disorders (ATPD; F23) as a hint for a closer relationship to... more
The aim of this study was to examine whether there is electroencephalographic evidence for an increased epileptiform activity in the EEG of ICD-10 acute and transient psychotic disorders (ATPD; F23) as a hint for a closer relationship to epilepsy. We analyzed the EEGs of 39 inpatients with ATPD, comparing them with 'positive' schizophrenic and bipolar schizoaffective controls matched for age and gender. The evaluation was performed visually and qualitatively using a rating scale of demonstrated reliability. We found no indication of an increased incidence of epileptiform discharges in ATPD compared with 'positive' schizophrenic and bipolar schizoaffective controls. The hypothesis of a relationship between ATPD and epilepsy could not be confirmed by EEG findings.
Publisher: content.karger.com
Publication Date: Jan 1, 2005
Publication Name: Psychopathology
Research Interests:
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by Raffaela Blöink and Frank Pillmann
ICD-10 acute and transient psychotic disorder (ATPD; F23) has one of its historical roots in the French concept of bouffée délirante. This study explores the empirical relationship of the two concepts. During a 5-year period, all... more
ICD-10 acute and transient psychotic disorder (ATPD; F23) has one of its historical roots in the French concept of bouffée délirante. This study explores the empirical relationship of the two concepts. During a 5-year period, all inpatients with ATPD were identified; the diagnosis of bouffée délirante was also determined. We systematically evaluated demographic and clinical features and carried out follow-up investigations at an average of 2.2 years after the index episode using standardized instruments. Forty-two (4.1%) of 1036 patients treated for psychotic disorders or major affective episode fulfilled the ICD-10 criteria of ATPD. Of these, only 28.6% also fulfilled the criteria of bouffée délirante. Patients with bouffée délirante were significantly younger than the remaining ATPD patients. Outcome parameters were generally more favourable for patients diagnosed with bouffée délirante than for ATPD patients without a concurrent diagnosis of bouffée délirante, but the difference was statistically significant only for occupational status. There are indications that a diagnosis of bouffée délirante carries a somewhat better prognosis than ATPD in general. However, the low frequency of operationally diagnosed bouffée délirante suggests that the criteria might be too narrow.
Publisher: Wiley Online Library
Publication Date: Jan 1, 2003
Publication Name: Australian and New Zealand Journal of Psychiatry
Research Interests: Psychiatry, Depression, Schizophrenia, Psychopathology, Comparative Study, and 18 moreLow Frequency, Humans, Age, Female, Classification, Male, Statistical Significance, Follow-up studies, Differential Diagnosis, Psychotic Disorder, International Classification of Diseases, Adult, Conceptualization, Psychotic Disorders, Nosology, Indexation, Severity of Illness Index, and Acute Disease(Low Frequency, Humans, Age, Female, Classification, Male, Statistical Significance, Follow-up studies, Differential Diagnosis, Psychotic Disorder, International Classification of Diseases, Adult, Conceptualization, Psychotic Disorders, Nosology, Indexation, Severity of Illness Index, and Acute Disease)
(Low Frequency, Humans, Age, Female, Classification, Male, Statistical Significance, Follow-up studies, Differential Diagnosis, Psychotic Disorder, International Classification of Diseases, Adult, Conceptualization, Psychotic Disorders, Nosology, Indexation, Severity of Illness Index, and Acute Disease)
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Is the psychopathology of acute and transient psychotic disorder different from schizophrenic and schizoaffective disorders?more
by Raffaela Blöink and Frank Pillmann
This study explores psychopathological aspects of acute and transient psychotic disorders (ATPD), a diagnostic category introduced with ICD-10, to elucidate its relationship with schizophrenia and schizoaffective psychoses. We recruited... more
This study explores psychopathological aspects of acute and transient psychotic disorders (ATPD), a diagnostic category introduced with ICD-10, to elucidate its relationship with schizophrenia and schizoaffective psychoses. We recruited all consecutive inpatients fulfilling the ICD-10 criteria of ATPD (F23) during a 5-year period as well as control groups with "positive" schizophrenia (PS) and bipolar schizoaffective disorder (BSAD) matched for gender and age at index episode. For the evaluation of psychopathological parameters during index episode a standardized symptom list was used. Prepsychotic (prodromal) symptoms were also assessed. During the prepsychotic period few differences between the groups were detected. The most important difference between ATPD and the other two other psychotic disorders regarding phenomenology of the full-blown episodes was a higher frequency of "rapidly changing delusional topics", "rapidly changing mood" and anxiety in ATPD. ATPD show a characteristic psychopathological picture consistent with earlier concepts such as cycloid psychoses and bouffée délirante. Nevertheless, psychopathology alone is not enough to establish ATPD as an independent nosological entity.
Publisher: ukpmc.ac.uk
Publication Date: Jan 1, 2005
Publication Name: European Psychiatry
Research Interests: Psychiatry, Schizophrenia, Bipolar Disorder, Psychopathology, Adolescent, and 16 moreDelusions, Humans, Hallucinations, Female, Male, Follow-up studies, Aged, Middle Aged, International Classification of Diseases, Adult, Psychotic Disorders, Indexation, Control Group, Psychiatric Status Rating Scales, Neuropsychological Tests, and Acute Disease
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by Raffaela Blöink and Frank Pillmann
Although a particularly vulnerable personality has been postulated by some authors as a pathogenetic factor in acute and transient psychotic disorders (ATPD) as introduced with ICD-10, little empirical work has been done on the subject.... more
Although a particularly vulnerable personality has been postulated by some authors as a pathogenetic factor in acute and transient psychotic disorders (ATPD) as introduced with ICD-10, little empirical work has been done on the subject. We therefore evaluated personality features and social interactions in a comparative study of patients with ATPD. We recruited all consecutive inpatients fulfilling the ICD-10 criteria of ATPD (F23) during a 5-year period, as well as control groups with "positive" schizophrenia (PS) and bipolar schizoaffective disorder (BSAD) matched for gender and age at index episode. For assessment of personality features and premorbid social contacts, we administered the NEO Five-Factor Inventory and a semi-structured interview. The assessment of the "Big Five" personality dimensions (neuroticism, extraversion, openness to experience, agreeableness, conscientiousness) with the NEO-FFI did not show any significant difference between ATPD patients and healthy controls. BSAD patients differed from mentally healthy controls on 2 of 5 subscales of the NEO-FFI (neuroticism, extraversion), but were otherwise indiscernible from ATPD patients and mentally healthy controls. In contrast, PS patients showed the most pronounced differences from the mentally healthy controls on the NEO-FFI, and had significantly less premorbid social interaction than the clinical controls. Within the limits of retrospective assessment, the present findings indicate that (1) patients with ATPD do not share the premorbid social impairment characteristic of schizophrenic patients and (2) the personality of patients with ATPD does not differ substantially from the general population.
Publisher: journals.lww.com
Publication Date: Jan 1, 2003
Publication Name: Journal of Nervous and Mental Disease
Research Interests: Psychology, Cognitive Science, Personality, Schizophrenia, Social Interaction, and 14 morePersonality Assessment, Humans, Personality Assessment Inventory, Hospitalization, Female, Male, The, Interpersonal Relations, Clinical Sciences, Adult, And, Psychotic Disorders, Psychiatric Status Rating Scales, and Acute Disease
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The relation of “acute and transient psychotic disorder” (ICD10 F23) to bipolar schizoaffective disordermore
by Raffaela Blöink and Frank Pillmann
The aim of this work is to investigate differences between acute and transient psychotic disorders (ATPD; F23 of ICD-10) and bipolar schizoaffective disorders (BSAD). In a controlled prospective and longitudinal study, we compared all... more
The aim of this work is to investigate differences between acute and transient psychotic disorders (ATPD; F23 of ICD-10) and bipolar schizoaffective disorders (BSAD). In a controlled prospective and longitudinal study, we compared all inpatients with ATPD treated at Halle university hospital during a 5-year period with matched controls with BSAD. Sociobiographical data were collected using a semi-structured interview. Follow-up investigations were performed at a mean of 2.2–3.3 years after the index episode or 8.2–16.1 years after the first episode by means of standardized instruments. ATPD differs significantly from BSAD on various relevant levels, such as gender (more female), age at onset (older), development of the full symptomatology (more rapid), duration of the symptomatology (shorter), acuteness of onset (more acute), preceding stressful life-events (more frequent) and long-term prognosis (better). It is concluded that ATPD and BSAD are different nosological entities.
Publication Date: Jan 1, 2002
Publication Name: Journal of Psychiatric Research
Research Interests: Schizophrenia, Bipolar Disorder, Sex, Prediction, Comparative Study, and 24 moreProspective studies, Humans, Outcome, Age, Female, Classification, Male, Psychotic Disorder, Seasonal variation, Middle Aged, Adult, Sex Factors, Longitudinal Study, Stressful Life Events, Prognosis, Psychotic Disorders, Psychiatric, Nosology, Indexation, Life Change Events, Age of Onset, Age at Onset, Severity of Illness Index, and Acute Disease(Prospective studies, Humans, Outcome, Age, Female, Classification, Male, Psychotic Disorder, Seasonal variation, Middle Aged, Adult, Sex Factors, Longitudinal Study, Stressful Life Events, Prognosis, Psychotic Disorders, Psychiatric, Nosology, Indexation, Life Change Events, Age of Onset, Age at Onset, Severity of Illness Index, and Acute Disease)
(Prospective studies, Humans, Outcome, Age, Female, Classification, Male, Psychotic Disorder, Seasonal variation, Middle Aged, Adult, Sex Factors, Longitudinal Study, Stressful Life Events, Prognosis, Psychotic Disorders, Psychiatric, Nosology, Indexation, Life Change Events, Age of Onset, Age at Onset, Severity of Illness Index, and Acute Disease)
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by Frank Pillmann and Raffaela Blöink
ICD-10 acute and transient psychotic disorder (ATPD; F23) and DSM-IV brief psychotic disorder (BPD; 298.8) are related diagnostic concepts, but little is known regarding the concordance of the two definitions. During a 5-year period all... more
ICD-10 acute and transient psychotic disorder (ATPD; F23) and DSM-IV brief psychotic disorder (BPD; 298.8) are related diagnostic concepts, but little is known regarding the concordance of the two definitions. During a 5-year period all in-patients with ATPD were identified; DSM-IV diagnoses were also determined. We systematically evaluated demographic and clinical features and carried out follow-up investigations at an average of 22 years after the index episode using standardized instruments. Forty-two (4.1%) of 1036 patients treated for psychotic disorders or major affective episode fulfilled the ICD-10 criteria of ATPD. Of these, 61.9% also fulfilled the DSM-IV criteria of brief psychotic disorder; 31.0%, of schizophreniform disorder; 2.4%, of delusional disorder; and 4.8%. of psychotic disorder not otherwise specified. BPD showed significant concordance with the polymorphic subtype of ATPD, and DSM-IV schizophreniform disorder showed significant concordance with the schizophreniform subtype of ATPD. BPD patients had a significantly shorter duration of episode and more acute onset compared with those ATPD patients who did not meet the criteria of BPD (non-BPD). However, the BPD group and the non-BPD group of ATPD were remarkably similar in terms of sociodemography (especially female preponderance), course and outcome, which was rather favourable for both groups. DSM-IV BPD is a psychotic disorder with broad concordance with ATPD as defined by ICD-10. However, the DSM-IV time criteria for BPD may be too narrow. The group of acute psychotic disorders with good prognosis extends beyond the borders of BPD and includes a subgroup of DSM-IV schizophreniform disorder.
Publication Date: Jan 1, 2002
Publication Name: Psychological Medicine
Research Interests: Psychology, Psychometrics, Schizophrenia, Psychological Medicine, Humans, and 14 morePsychological, Female, Male, Follow-up studies, Psychotic Disorder, Patient Admission, Middle Aged, Adult, Public health systems and services research, Reproducibility of Results, Psychotic Disorders, Neurosciences, Psychiatric Status Rating Scales, and Acute Disease
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by Frank Pillmann and Raffaela Blöink