In this Letter we present the discovery of imidazo[1,2-a]pyridines as a new series of mGluR2 PAMs. With the need to identify new hit matter for this target we applied computational techniques based on 3D shape and electrostatic...
moreIn this Letter we present the discovery of imidazo[1,2-a]pyridines as a new series of mGluR2 PAMs. With the need to identify new hit matter for this target we applied computational techniques based on 3D shape and electrostatic similarity. Such approaches are well suited to ...