All times Eastern. Rankings from AP Poll.
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| First round Tuesday, March 10 | | | Second round Wednesday, March 11 | | | Quarterfinals Thursday, March 12 | | | Semifinals Friday, March 13 | | | Final Saturday, March 14 |
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| | 1 | #5 Louisville | 73 |
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| | 8 | Providence | 83 | | | 8 | Providence | 55 | | | |
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| 9 | Cincinnati | 57 | | | 16 | DePaul | 74 | | | | 1 | #5 Louisville | 69 |
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| 16 | DePaul | 67 | | | | | | 4 | #10 Villanova | 55 | | |
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| | | 4 | #10 Villanova | 76 | |
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| | 5 | #21 Marquette | 74 | | | 5 | #21 Marquette | 75 | | | |
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| 12 | Georgetown | 59 | | | 13 | St. John's | 45 | | | | 1 | #5 Louisville | 76 |
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| 13 | St. John's | 64 | | | | | | 6 | #18 Syracuse | 66 |
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| | | 2 | #2 Pittsburgh | 60 | |
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| | 7 | West Virginia | 74 | | | 7 | West Virginia | 74 | | | |
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| 10 | Notre Dame | 61 | | | 10 | Notre Dame | 62 | | | | 7 | West Virginia | 69 |
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| 15 | Rutgers | 50 | | | | | | 6 | #18 Syracuse | 74OT | | |
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| | | 3 | #3 Connecticut | 117 | |
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| | 6 | #18 Syracuse | 89 | | | 6 | #18 Syracuse | 1276OT | | |
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| 11 | Seton Hall | 68 | | | 11 | Seton Hall | 74 | | | |
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| 14 | South Florida | 54 | | | |
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Thursday, March 12 7:00 pm
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Madison Square Garden, New York City, New York Attendance: 19,375 Referees: Jim Burr, Wally Rutecki, Michael Stephens
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Syracuse vs. Connecticut
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The quarterfinal game on Thursday, March 12 between Syracuse and Connecticut lasted for six overtime periods, the second-longest game in NCAA Division I Men's Basketball history. The record is a seven overtime game from December 21, 1981, in which Cincinnati outlasted Bradley 75–73, in a game that took place before the implementation of the shot clock. Syracuse beat Connecticut 127–117 without having the lead in any of the first five overtimes.[3] The game tipped off at 9:36 PM ET and ended at 1:22 AM ET on Friday March 13; in the 3 hours and 46 minutes it took to play the game, a combined total of 244 points were scored (102 of which were scored in overtime), 211 field-goals attempted (103 in overtime), 93 free throws attempted, 66 fouls committed with four players on each team fouling out.