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According to the German Wikipedia [^1], Chlormadinone acetate shares an increased risk of venous thromboembolism (VTE) [^2] or meningonoma (benign brain tumors). [^3]
For VTE, the estimated incidence is 6-9/10_000 (CMA group) vs. 2/10_000 (baseline) [^2]
[^1]: https://de.wikipedia.org/wiki/Chlormadinon#Nebenwirkungen
[^2]: https://www.pharmazeutische-zeitung.de/leicht-erhoehtes-thrombose-risiko-bei-pillen-mit-chlormadinon-145709/
[^3]: https://www.ema.europa.eu/en/news/medicines-containing-nomegestrol-or-chlormadinone-prac-recommends-new-measures-minimise-risk-meningioma 2003:D3:8714:FA00:A60B:9C2D:84D4:F6EE (talk) 13:51, 12 May 2024 (UTC)[reply]
- Note that this contradicts to this version of the article, which claims "CMA does not increase the risk of venous thromboembolism."
- On the other hand, it is unclear whether the German findings concerning CMA+EE are applicable to CMA alone, or whether the risk assessment might be different concerning CMA use in males. 2003:D3:8714:FA00:A60B:9C2D:84D4:F6EE (talk) 13:58, 12 May 2024 (UTC)[reply]