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Small nucleolar RNA TBR5 |
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PDB structures | PDBe |
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TBR5 is a member of the C/D class of snoRNA which contain the C (UGAUGA) and D (CUGA) box motifs. Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs [1,2].
References
- [1] Galardi, S (2002). "Purified box C/D snoRNPs are able to reproduce site-specific 2'-O-methylation of target RNA in vitro". Mol Cell Biol. 22: 6663–6668. doi:10.1128/MCB.22.19.6663-6668.2002. PMID 12215523.
- [2] Dunbar, DA (2000). "Fibrillarin-associated box C/D small nucleolar RNAs in Trypanosoma brucei. Sequence conservation and implications for 2'-O-ribose methylation of rRNA". J Biol Chem. 275: 14767–14776. doi:10.1074/jbc.M001180200. PMID 10747997. CS1 maint: unflagged free DOI (link)
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