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Mibolerone

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This is an old revision of this page, as edited by Exitar (talk | contribs) at 09:25, 27 December 2011 (Removed image, as it is either incorrect or describes the synthesis of bolasterone, as is evident from the presence of the 19 carbon.). The present address (URL) is a permanent link to this revision, which may differ significantly from the current revision.

Mibolerone
Clinical data
Other names(7R,8R,9S,10R,13S,14S,17S)-17-Hydroxy-7,13,17-trimethyl-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one
AHFS/Drugs.comInternational Drug Names
Routes of
administration
Oral
ATC code
  • none
Legal status
Legal status
  • Schedule 3 (US)
Pharmacokinetic data
MetabolismHepatic
Elimination half-life2-4 hours
Identifiers
  • (7α,17β)-17-hydroxy-7,17-dimethylestr-4-en-3-one
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.020.951 Edit this at Wikidata
Chemical and physical data
FormulaC20H30O2
Molar mass302.4558 g/mol g·mol−1
3D model (JSmol)
  • O=C4\C=C3/[C@@H]([C@H]2CC[C@]1([C@@H](CC[C@@]1(O)C)[C@@H]2[C@H](C)C3)C)CC4
  • InChI=1S/C20H30O2/c1-12-10-13-11-14(21)4-5-15(13)16-6-8-19(2)17(18(12)16)7-9-20(19,3)22/h11-12,15-18,22H,4-10H2,1-3H3/t12-,15+,16-,17+,18-,19+,20+/m1/s1 checkY
  • Key:PTQMMNYJKCSPET-OMHQDGTGSA-N checkY
 ☒NcheckY (what is this?)  (verify)

Mibolerone is a potent anabolic steroid which is both higher affinity[1] and more selective[2] for the androgen receptor than metribolone.

References

  1. ^ Murthy LR, Johnson MP, Rowley DR, Young CY, Scardino PT, Tindall DJ (1986). "Characterization of steroid receptors in human prostate using mibolerone". Prostate. 8 (3): 241–53. doi:10.1002/pros.2990080305. PMID 2422638.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  2. ^ Schilling K, Liao S (1984). "The use of radioactive 7 alpha, 17 alpha-dimethyl-19-nortestosterone (mibolerone) in the assay of androgen receptors". Prostate. 5 (6): 581–8. doi:10.1002/pros.2990050603. PMID 6333679.