Insights

Insight articles are related to original research papers in eLife and explain why the results reported in the paper are significant in a given field of research. Insight articles are commissioned by eLife staff.

Latest articles

    1. Neuroscience

    Behavior: Prompting social investigation

    Emma Keppler, Susanna Molas
    A social memory pathway connecting the ventral hippocampus, the lateral septum and the ventral tegmental area helps to regulate how mice react to unknown individuals.
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    1. Neuroscience

    Vision: Paying attention

    Christian H Poth
    Intentional eye movements depend on where peripheral attention is voluntarily deployed beforehand, but they can be directed elsewhere shortly afterwards.
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    1. Evolutionary Biology

    Synthetic Biology: Shining a light on Ohno’s dilemma

    Isabella Tomanek
    Laboratory experiments on a fluorescent protein in E. coli reveal how duplicate genes are rapidly inactivated by mutations during evolution.
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    1. Plant Biology

    Plant Cell Wall: Interplay between structure and signaling

    David Biermann, Sebastian Wolf
    Modification of pectin, a component of the plant cell wall, is required to facilitate signaling by a RALF peptide, which is essential for many physiological and developmental processes.
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    1. Cell Biology

    Membrane Fusion: A matter of timing

    Zhiqi Tian, Jiajie Diao
    A change in the electric charge of autophagosome membranes controls the recruitment of SNARE proteins to ensure that membrane fusion occurs at the right time during autophagy.
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    1. Cell Biology

    Muscle Cells: Tailoring the taste of cultured meat

    Gyuhyung Jin, Xiaoping Bao
    A new protocol can customize the flavor of lab-grown meat by controlling the level of fat deposited between muscle cells.
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    1. Structural Biology and Molecular Biophysics

    Signaling: The tale of capturing Norrin

    Hsin-Yi Henry Ho
    Detailed binding experiments reveal new insights into the Norrin/Wnt signaling pathway that helps to control vascularization in the retina.
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    1. Cell Biology
    2. Structural Biology and Molecular Biophysics

    Biosynthesis: RAMPing up knowledge of the translocon

    Dimitrios Vismpas, Friedrich Förster
    Advanced cryo-EM approaches reveal surprising insights into the molecular structure that allows nascent proteins to be inserted into the membrane of the endoplasmic reticulum.
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    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Disease Surveillance: Monitoring livestock pregnancy loss

    Clara Akpan
    Systematically tracking and analysing reproductive loss in livestock helps with efforts to safeguard the health and productivity of food animals by identifying causes and high-risk areas.
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    1. Cancer Biology
    2. Cell Biology

    Exosomes: How tumors escape the immune system

    Stefanie Schmieder
    Mutations in the gene for β-catenin cause liver cancer cells to release fewer exosomes, which reduces the number of immune cells infiltrating the tumor.
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