Korean Journal of Anesthesiology

Comparison of analgesic effects between programmed intermittent epidural boluses and continuous epidural infusion after cesarean section: a randomized controlled study: Yu Jeong Bang, Heejoon Jeong, RyungA Kang, Ji-Hee Sung, Suk-Joo Choi, et al.; Korean J Anesthesiol. 2024;77(3):374-383.

Review Article

January 17, 2024

Intraoperative pediatric electroencephalography monitoring: an updated review

Ian Yuan, Choon L. Bong, Jerry Y. Chao

Korean J Anesthesiol. 2024;77(3):289-305.

Intraoperative electroencephalography (EEG) monitoring under pediatric anesthesia has begun to attract increasing interest, driven by the availability of pediatric-specific EEG monitors and the realization that traditional dosing methods based on patient movement or changes in hemodynamic response often lead to imprecise dosing, especially in younger infants who may experience adverse events (e.g., hypotension) due to excess anesthesia. EEG directly measures the effects of anesthetics on the brain, which is the target end-organ responsible for inducing loss of consciousness. Over the past ten years, research on anesthesia and computational neuroscience has improved our understanding of intraoperative pediatric EEG monitoring and expanded the utility of EEG in clinical practice. ...

Review Article

January 29, 2024

Perioperative management of patients with cardiac implantable electronic devices

Minsu Kim, Chang Hee Kwon

Korean J Anesthesiol. 2024;77(3):306-315.

The use of cardiac implantable electronic devices (CIEDs) has increased significantly in recent years. Consequently, more patients with CIEDs will undergo surgery during their lifetime, and thus the involvement of anesthesiologists in the perioperative management of CIEDs is increasing. With ongoing advancements in technology, many types of CIEDs have been developed, including permanent pacemakers, leadless pacemakers, implantable cardioverter defibrillators, cardiac resynchronization therapy-pacemakers/defibrillators, and implantable loop recorders. The functioning of CIEDs exposed to an electromagnetic field can be affected by electromagnetic interference, potential sources of which can be found in the operating room. Thus, to prevent potential adverse events caused by electromagnetic interference in the operating room, anesthesiologists must have knowledge...

Statistical Round

April 29, 2024

Alternatives to the P value: connotations of significance

Junyong In, Dong Kyu Lee

Korean J Anesthesiol. 2024;77(3):316-325.

The statistical significance of a clinical trial analysis result is determined by a mathematical calculation and probability based on null hypothesis significance testing. However, statistical significance does not always align with meaningful clinical effects; thus, assigning clinical relevance to statistical significance is unreasonable. A statistical result incorporating a clinically meaningful difference is a better approach to present statistical significance. Thus, the minimal clinically important difference (MCID), which requires integrating minimum clinically relevant changes from the early stages of research design, has been introduced. As a follow-up to the previous statistical round article on P values, confidence intervals, and effect sizes, in this article, we present hands-on examples of MCID and...

Clinical Research Article

February 20, 2024

Comparison of preemptive and preventive intravenous acetaminophen on opioid consumption in pediatrics undergoing posterior spinal fusion surgery: a randomized controlled trial

Yeon Ju Kim, Ha-Jung Kim, Sehee Kim, Hyungtae Kim, Choon Sung Lee, et al.

Korean J Anesthesiol. 2024;77(3):326-334.

Background: Posterior spinal fusion (PSF), commonly used for adolescent idiopathic scoliosis (AIS), causes severe postoperative pain. Intravenous (IV) administration of acetaminophen has shown promise for opioid-sparing analgesia; however, its analgesic effect and optimal timing for its standard use remain unclear. Our study aimed to evaluate the analgesic effect and optimal timing of IV acetaminophen administration in pediatric and adolescent patients undergoing PSF and requiring adequate pain control. Methods: This prospective, randomized, triple-blind trial was conducted in patients aged 11–20 undergoing PSF. Participants were randomized into three groups: the preemptive group (received...

Clinical Research Article

February 5, 2024

Comparison of effects of telmisartan versus valsartan on post-induction hypotension during noncardiac surgery: a prospective observational study

Chung-Sik Oh, Jun Young Park, Seong-Hyop Kim

Korean J Anesthesiol. 2024;77(3):335-344.

Background: Telmisartan is considered more potent than valsartan. Hemodynamic response during anesthesia induction may be influenced by anti-hypertension (HTN) medication. The present study compared the effect of anti-HTN medications on post-induction hypotension during noncardiac surgeries. Methods: This observational study standardized the anesthetic regimen across patients, with hypotension defined as mean blood pressure (BP) of less than 65 mmHg. The hemodynamic changes within 5 min before and after endotracheal intubation, and within 10 min before and after surgical incision were measured. Transthoracic echocardiographic evaluation of the left ventricle (LV) during anesthesia induction...

Clinical Research Article

March 12, 2024

Efficacy of intraoperative blood salvage and autotransfusion in living-donor liver transplantation: a retrospective cohort study

Jongchan Lee, Sujung Park, Jae Geun Lee, Sungji Choo, Bon-Nyeo Koo

Korean J Anesthesiol. 2024;77(3):345-352.

Background: Liver transplantation (LT) may be associated with massive blood loss and the need for allogeneic blood transfusion. Intraoperative blood salvage autotransfusion (IBSA) can reduce the need for allogeneic blood transfusion. This study aimed to investigate the effectiveness of blood salvage in LT. Methods: Among 355 adult patients who underwent elective living-donor LT between January 1, 2019, and December 31, 2022, 59 recipients without advanced hepatocellular carcinoma received IBSA using Cell Saver (CS group). Based on sex, age, model for end-stage liver disease (MELD) score, preoperative laboratory results, and other factors, 118 of the 296 recipients who did not undergo IBSA were matched using propensity score (non-CS group). The primary outcome...

Clinical Research Article

March 5, 2024

Comparison of lung aeration loss in open abdominal oncologic surgeries after ventilation with electrical impedance tomography-guided PEEP versus conventional PEEP: a pilot feasibility study

A. R. Karthik, Nishkarsh Gupta, Rakesh Garg, Sachidanand Jee Bharati, M. D. Ray, et al.

Korean J Anesthesiol. 2024;77(3):353-363.

Background: Existing literature lacks high-quality evidence regarding the ideal intraoperative positive end-expiratory pressure (PEEP) to minimize postoperative pulmonary complications (PPCs). We hypothesized that applying individualized PEEP derived from electrical impedance tomography would reduce the severity of postoperative lung aeration loss, deterioration in oxygenation, and PPC incidence. Methods: A pilot feasibility study was conducted on 36 patients who underwent open abdominal oncologic surgery. The patients were randomized to receive individualized PEEP or conventional PEEP at 4 cmH2O. The primary outcome was the impact of individualized PEEP on changes in the modified lung...

Clinical Research Article

March 14, 2024

The minimum effective concentration (MEC90) of bupivacaine for an ultrasound-guided suprainguinal fascia iliaca compartment block for analgesia in knee surgery: a dose-finding study

Caner Genc, Serkan Tulgar, Murat Unal, Ahmet Serhat Genc, Lokman Kehribar, et al.

Korean J Anesthesiol. 2024;77(3):364-373.

Background: In recent years, the suprainguinal fascia iliaca compartment block (SFICB) has become more common in clinical practice. This assessor-blinded dose-finding study aimed to determine the minimum effective concentration (MEC90, MEC95) of bupivacaine for a single-injection SFICB in patients undergoing arthroscopic anterior cruciate ligament repair. Methods: This prospective study was conducted at a tertiary hospital (postoperative recovery room and ward). The SFICB was performed as a postsurgical intervention after spinal anesthesia. Seventy patients were allocated using the biased-coin design up-and-down sequential method. The ultrasound-guided...

Clinical Research Article

March 14, 2024

Comparison of analgesic effects between programmed intermittent epidural boluses and continuous epidural infusion after cesarean section: a randomized controlled study

Yu Jeong Bang, Heejoon Jeong, RyungA Kang, Ji-Hee Sung, Suk-Joo Choi, et al.

Korean J Anesthesiol. 2024;77(3):374-383.

Background: This study aimed to compare the analgesic effects of programmed intermittent epidural boluses (PIEB) and continuous epidural infusion (CEI) for postoperative analgesia after elective cesarean section (CS). Methods: Seventy-four women who underwent elective CS were randomized to receive either PIEB or CEI. The PIEB group received 4 ml-intermittent boluses of 0.11% ropivacaine every hour at a rate of 120 ml/h. The CEI group received a constant rate of 4 ml/h of 0.11% ropivacaine. The primary outcome was the pain score at rest at 36 h after CS. Secondary outcomes included...

Experimental Research Article

February 15, 2024

Caenorhabditis elegans">Neuroprotective effect of erythropoietin on anesthesia-induced neurotoxicity through the modulation of autophagy in Caenorhabditis elegans

Bon-Wook Koo, Hyun-Jung Shin, Sooyoung Jeon, Jung Hyun Bang, Sang-Hwan Do, et al.

Korean J Anesthesiol. 2024;77(3):384-391.

Background: The anti-oxidative, anti-inflammatory, and anti-apoptotic effects of erythropoietin may provide neuroprotective effects. Erythropoietin also modulates autophagy signaling that may play a role in anesthesia-induced neurotoxicity (AIN). Herein, we investigated whether AIN can be attenuated by the neuroprotective effect of erythropoietin in the Caenorhabditis elegans (C. elegans). Methods: Synchronized worms were divided into the control, Iso, EPO, and EPO-Iso groups. The chemotaxis index (CI) was evaluated when they reached the young adult stage. The lgg-1::GFP-positive puncta per seam cell were used to determine the autophagic events. The erythropoietin-mediated pathway of autophagy...

Programmed intermittent epidural bolus: a viable alternative to traditional methods? Seunguk Bang Korean J Anesthesiol. 2024;77(3):287-288. Editorial May 23, 2024 Full text PubReader ePub PDF	Intraoperative pediatric electroencephalography monitoring: an updated review Ian Yuan, Choon L. Bong, Jerry Y. Chao Korean J Anesthesiol. 2024;77(3):289-305. Review Article January 17, 2024 Full text PubReader ePub PDF PDF(Korean)
Perioperative management of patients with cardiac implantable electronic devices Minsu Kim, Chang Hee Kwon Korean J Anesthesiol. 2024;77(3):306-315. Review Article January 29, 2024 Full text PubReader ePub PDF PDF(Korean)	Alternatives to the P value: connotations of significance Junyong In, Dong Kyu Lee Korean J Anesthesiol. 2024;77(3):316-325. Statistical Round April 29, 2024 Full text PubReader ePub PDF PDF(Korean) Supplementary Material
Comparison of preemptive and preventive intravenous acetaminophen on opioid consumption in pediatrics undergoing posterior spinal fusion surgery: a randomized controlled trial Yeon Ju Kim, Ha-Jung Kim, Sehee Kim, Hyungtae Kim, Choon Sung Lee, Chang Ju Hwang, Jae Hwan Cho, Young-Jin Ro, Won Uk Koh Korean J Anesthesiol. 2024;77(3):326-334. Clinical Research Article February 20, 2024 Full text PubReader ePub PDF PDF(Korean) Supplementary Material	Comparison of effects of telmisartan versus valsartan on post-induction hypotension during noncardiac surgery: a prospective observational study Chung-Sik Oh, Jun Young Park, Seong-Hyop Kim Korean J Anesthesiol. 2024;77(3):335-344. Clinical Research Article February 5, 2024 Full text PubReader ePub PDF PDF(Korean) Supplementary Material
Efficacy of intraoperative blood salvage and autotransfusion in living-donor liver transplantation: a retrospective cohort study Jongchan Lee, Sujung Park, Jae Geun Lee, Sungji Choo, Bon-Nyeo Koo Korean J Anesthesiol. 2024;77(3):345-352. Clinical Research Article March 12, 2024 Full text PubReader ePub PDF PDF(Korean)	Comparison of lung aeration loss in open abdominal oncologic surgeries after ventilation with electrical impedance tomography-guided PEEP versus conventional PEEP: a pilot feasibility study A. R. Karthik, Nishkarsh Gupta, Rakesh Garg, Sachidanand Jee Bharati, M. D. Ray, Vijay Hadda, Sourabh Pahuja, Seema Mishra, Sushma Bhatnagar, Vinod Kumar Korean J Anesthesiol. 2024;77(3):353-363. Clinical Research Article March 5, 2024 Full text PubReader ePub PDF PDF(Korean) Supplementary Material
The minimum effective concentration (MEC90) of bupivacaine for an ultrasound-guided suprainguinal fascia iliaca compartment block for analgesia in knee surgery: a dose-finding study Caner Genc, Serkan Tulgar, Murat Unal, Ahmet Serhat Genc, Lokman Kehribar, Basar Erdivanli, Kris Vermeylen, Ersin Koksal Korean J Anesthesiol. 2024;77(3):364-373. Clinical Research Article March 14, 2024 Full text PubReader ePub PDF PDF(Korean)	Comparison of analgesic effects between programmed intermittent epidural boluses and continuous epidural infusion after cesarean section: a randomized controlled study Yu Jeong Bang, Heejoon Jeong, RyungA Kang, Ji-Hee Sung, Suk-Joo Choi, Soo-Young Oh, Tae Soo Hahm, Young Hee Shin, Yeon Woo Jeong, Soo Joo Choi, et al. Korean J Anesthesiol. 2024;77(3):374-383. Clinical Research Article March 14, 2024 Cited By 1 Full text PubReader ePub PDF PDF(Korean) Supplementary Material
Caenorhabditis elegans"> Neuroprotective effect of erythropoietin on anesthesia-induced neurotoxicity through the modulation of autophagy in Caenorhabditis elegans Bon-Wook Koo, Hyun-Jung Shin, Sooyoung Jeon, Jung Hyun Bang, Sang-Hwan Do, Hyo-Seok Na Korean J Anesthesiol. 2024;77(3):384-391. Experimental Research Article February 15, 2024 Full text PubReader ePub PDF PDF(Korean) Supplementary Material	Use of the Disposcope endoscope for awake orotracheal intubation in an elderly patient with a large vocal cord polyp -a case report- Duo Yang, Sen Li, Jinxin Lan, Shujun Ye, Longsheng Zhang Korean J Anesthesiol. 2024;77(3):392-396. Case Report March 11, 2024 Full text PubReader ePub PDF
Intraoperative tourniquet-induced hyperthermia in a pediatric patient: a forgotten association -a case report- Tarek Tageldin, Muhammad Jaffar Khan, Temur Baykuziyev, Haitham Ahmed Korean J Anesthesiol. 2024;77(3):397-400. Case Report January 4, 2024 Full text PubReader ePub PDF	Sudden ventricular fibrillation due to absence of pericardium in left upper lobectomy -a case report- Guo-Cao Wang, Xi-Rong Li, Ning Huang, Hai-Tao Tian Korean J Anesthesiol. 2024;77(3):401-404. Case Report January 16, 2024 Full text PubReader ePub PDF Supplementary Material
Comment on "Comparison of the pericapsular nerve group block with the intra-articular and quadratus lumborum blocks in primary total hip arthroplasty: a randomized controlled trial" Anju Gupta, Nitin Choudhary, Nishkarsh Gupta Korean J Anesthesiol. 2024;77(3):405-406. Letter to the Editor March 27, 2024 Full text PubReader ePub PDF	Response to "Comment on Single-shot regional anesthesia for laparoscopic cholecystectomies: a systematic review and network meta-analysis" Alessandro De Cassai, Federico Geraldini Korean J Anesthesiol. 2024;77(3):406-407. Letter to the Editor March 19, 2024 Full text PubReader ePub PDF