Reciprocal regulation of neu tyrosine kinase activity and caveolin-1 protein expression in vitro and in vivo. Implications for human breast cancer (Q24318999)

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English	Reciprocal regulation of neu tyrosine kinase activity and caveolin-1 protein expression in vitro and in vivo. Implications for human breast cancer	scientific article

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9685399%20AND%20SRC:MED&resulttype=core&format=json

13 November 2019

Reciprocal regulation of neu tyrosine kinase activity and caveolin-1 protein expression in vitro and in vivo. Implications for human breast cancer (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9685399%20AND%20SRC:MED&resulttype=core&format=json

13 November 2019

Erb-b2 receptor tyrosine kinase 2

1 reference

GOA release 2020-03-11

cell surface receptor signaling pathway

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GOA release 2020-03-11

Caveolin 1, caveolae protein

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GOA release 2020-03-11

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David J. Bearss

4

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13 November 2019

8

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13 November 2019

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J A Engelman

1

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13 November 2019

R J Lee

2

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13 November 2019

A Karnezis

3

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13 November 2019

M Webster

5

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13 November 2019

P Siegel

6

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13 November 2019

W J Muller

7

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13 November 2019

R G Pestell

9

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13 November 2019

M P Lisanti

10

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13 November 2019

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1 August 1998

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13 November 2019

Journal of Biological Chemistry

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13 November 2019

273

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13 November 2019

32

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13 November 2019

20448-20455

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13 November 2019

Amplification of a novel v-erbB-related gene in a human mammary carcinoma.

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c-erbB-2 protein overexpression in breast cancer is a risk factor in patients with involved and uninvolved lymph nodes

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Heterodimerization and functional interaction between EGF receptor family members: a new signaling paradigm with implications for breast cancer research

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neu(c-erbB-2/HER2) and the epidermal growth factor receptor (EGFR) in breast cancer

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Neu and its ligands: from an oncogene to neural factors

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Stochastic appearance of mammary tumors in transgenic mice carrying the MMTV/c-neu oncogene

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Single-step induction of mammary adenocarcinoma in transgenic mice bearing the activated c-neu oncogene

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Expression of the neu protooncogene in the mammary epithelium of transgenic mice induces metastatic disease

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Caveolin isoforms differ in their N-terminal protein sequence and subcellular distribution. Identification and epitope mapping of an isoform-specific monoclonal antibody probe

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21 January 2018

Cell-type and tissue-specific expression of caveolin-2. Caveolins 1 and 2 co-localize and form a stable hetero-oligomeric complex in vivo

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Characterization of cell lines showing growth control isolated from both the wild type and a leucyl-tRNA synthetase mutant of chinese hamster ovary cells

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Src tyrosine kinases, Galpha subunits, and H-Ras share a common membrane-anchored scaffolding protein, caveolin. Caveolin binding negatively regulates the auto-activation of Src tyrosine kinases

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Induction of mammary epithelial hyperplasias and mammary tumors in transgenic mice expressing a murine mammary tumor virus/activated c-src fusion gene

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Antigen retrieval in cryostat tissue sections and cultured cells by treatment with sodium dodecyl sulfate (SDS).

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Recombinant expression of caveolin-1 in oncogenically transformed cells abrogates anchorage-independent growth

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Reduction of caveolin and caveolae in oncogenically transformed cells

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Mutational analysis of the properties of caveolin-1. A novel role for the C-terminal domain in mediating homo-typic caveolin-caveolin interactions

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Interaction of a receptor tyrosine kinase, EGF-R, with caveolins. Caveolin binding negatively regulates tyrosine and serine/threonine kinase activities

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Caveolin interaction with protein kinase C. Isoenzyme-dependent regulation of kinase activity by the caveolin scaffolding domain peptide.

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Coexpression of MMTV/v-Ha-ras and MMTV/c-myc genes in transgenic mice: synergistic action of oncogenes in vivo

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Caveolae, caveolin and caveolin-rich membrane domains: a signalling hypothesis

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Molecular and cellular biology of caveolae paradoxes and plasticities

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Evidence for a regulated interaction between heterotrimeric G proteins and caveolin

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Co-purification and direct interaction of Ras with caveolin, an integral membrane protein of caveolae microdomains. Detergent-free purification of caveolae microdomains

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Identification, sequence, and expression of caveolin-2 defines a caveolin gene family

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Molecular cloning of caveolin-3, a novel member of the caveolin gene family expressed predominantly in muscle

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M-caveolin, a muscle-specific caveolin-related protein.

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Oligomeric structure of caveolin: implications for caveolae membrane organization

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Identification of peptide and protein ligands for the caveolin-scaffolding domain. Implications for the interaction of caveolin with caveolae-associated proteins

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Platelet-derived growth factor activates mitogen-activated protein kinase in isolated caveolae

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