Serpin family I member 1 (Q21134355)

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Revision as of 10:03, 23 January 2024 by Charles Matthews (talk | contribs) (‎Created claim: MeSH tree code (P672): D12.776.872.488)

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mammalian protein found in Homo sapiens

PI-12
serpin peptidase inhibitor, clade I (neuroserpin), member 1
peptidase inhibitor 12
serpin I1
serine (or cysteine) proteinase inhibitor, clade I (neuroserpin), member 1
serpin peptidase inhibitor clade I member 1
SERPINI1
neuroserpin

Language	Label	Description	Also known as
English	Serpin family I member 1	mammalian protein found in Homo sapiens	PI-12 serpin peptidase inhibitor, clade I (neuroserpin), member 1 peptidase inhibitor 12 serpin I1 serine (or cysteine) proteinase inhibitor, clade I (neuroserpin), member 1 serpin peptidase inhibitor clade I member 1 SERPINI1 neuroserpin

Statements

1 reference

13 November 2019

UniProt protein ID

1 reference

1 December 2016

UniProt protein ID

Serpin superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q99574

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q99574

Serpin, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

Serpin domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

peptidase inhibitor activity

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99574

determination method

serine-type endopeptidase inhibitor activity

determination method

4 references

26 September 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99574&geneProductId=UniProtKB:Q99574

determination method

26 September 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99574&geneProductId=UniProtKB:Q99574

determination method

26 September 2017

The axonally secreted serine proteinase inhibitor, neuroserpin, inhibits plasminogen activators and plasmin but not thrombin

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99574&geneProductId=UniProtKB:Q99574

determination method

26 September 2017

The 2.1-A crystal structure of native neuroserpin reveals unique structural elements that contribute to conformational instability

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99574&geneProductId=UniProtKB:Q99574

determination method

serine-type endopeptidase inhibitor activity

determination method

5 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99574

determination method

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99574

determination method

8 April 2019

The 2.1-A crystal structure of native neuroserpin reveals unique structural elements that contribute to conformational instability

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99574

determination method

8 April 2019

The axonally secreted serine proteinase inhibitor, neuroserpin, inhibits plasminogen activators and plasmin but not thrombin

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99574

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99574

determination method

extracellular region

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99574

determination method

extracellular exosome

determination method

secretory granule lumen

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99574

determination method

cytoplasmic vesicle lumen

determination method

1 reference

8 April 2019

Identification of a novel targeting sequence for regulated secretion in the serine protease inhibitor neuroserpin.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99574

determination method

extracellular space

determination method

3 references

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99574&geneProductId=UniProtKB:Q99574

determination method

26 September 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99574&geneProductId=UniProtKB:Q99574

determination method

26 September 2017

Identification of a novel targeting sequence for regulated secretion in the serine protease inhibitor neuroserpin.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99574&geneProductId=UniProtKB:Q99574

determination method

cytoplasmic vesicle

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99574

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99574

determination method

extracellular space

determination method

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99574

determination method

8 April 2019

Identification of a novel targeting sequence for regulated secretion in the serine protease inhibitor neuroserpin.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99574

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99574

determination method

extracellular exosome

determination method

1 reference

8 April 2019

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99574

determination method

biological process

central nervous system development

determination method

1 reference

8 April 2019

Human neuroserpin (PI12): cDNA cloning and chromosomal localization to 3q26

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99574

determination method

negative regulation of peptidase activity

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99574

determination method

regulation of cell adhesion

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99574

determination method

peripheral nervous system development

determination method

1 reference

8 April 2019

Human neuroserpin (PI12): cDNA cloning and chromosomal localization to 3q26

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99574

determination method

negative regulation of endopeptidase activity

determination method

1 reference

26 September 2017

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99574&geneProductId=UniProtKB:Q99574

determination method

positive regulation of neuron projection development

determination method

1 reference

26 September 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99574&geneProductId=UniProtKB:Q99574

determination method

negative regulation of endopeptidase activity

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99574

determination method

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q99574

Serpin, conserved site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q99574

Identifiers

MeSH descriptor ID

subject named as

Neuroserpin

0 references

D12.644.861.488

0 references

D12.776.872.488

0 references

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000295777

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000295777

ENSP00000397373

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000397373

ENSP00000420133

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000420133

ENSP00000420561

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000420561

ENSP00000420807

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000420807

PDB structure ID

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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