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Mechanism of TGFbeta receptor inhibition by FKBP12 - Wikidata

Mechanism of TGFbeta receptor inhibition by FKBP12 (Q41101968)

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scientific article published on July 1997

Language	Label	Description	Also known as
English	Mechanism of TGFbeta receptor inhibition by FKBP12	scientific article published on July 1997

Statements

scholarly article

1 reference

Europe PubMed Central

PMC publication ID

26 September 2017

Mechanism of TGFbeta receptor inhibition by FKBP12 (English)

1 reference

Europe PubMed Central

PMC publication ID

26 September 2017

author name string

Y G Chen

1

1 reference

Europe PubMed Central

PMC publication ID

26 September 2017

F Liu

2

1 reference

Europe PubMed Central

PMC publication ID

26 September 2017

J Massague

3

1 reference

Europe PubMed Central

PMC publication ID

26 September 2017

language of work or name

0 references

publication date

1 July 1997

1 reference

Europe PubMed Central

PMC publication ID

26 September 2017

The EMBO Journal

1 reference

Europe PubMed Central

PMC publication ID

26 September 2017

16

1 reference

Europe PubMed Central

PMC publication ID

26 September 2017

13

1 reference

Europe PubMed Central

PMC publication ID

26 September 2017

3866-3876

1 reference

Europe PubMed Central

PMC publication ID

26 September 2017

The TGF-beta family mediator Smad1 is phosphorylated directly and activated functionally by the BMP receptor kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170011

26 September 2017

MADR2 is a substrate of the TGFbeta receptor and its phosphorylation is required for nuclear accumulation and signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170011

26 September 2017

A transcriptional partner for MAD proteins in TGF-beta signalling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170011

26 September 2017

Dorsoventral patterning in Xenopus: inhibition of ventral signals by direct binding of chordin to BMP-4.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170011

26 September 2017

MADR2 maps to 18q21 and encodes a TGFbeta-regulated MAD-related protein that is functionally mutated in colorectal carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170011

26 September 2017

TGFbeta signaling: receptors, transducers, and Mad proteins.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170011

26 September 2017

Ligand-independent activation of transforming growth factor (TGF) beta signaling pathways by heteromeric cytoplasmic domains of TGF-beta receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170011

26 September 2017

MADR1, a MAD-related protein that functions in BMP2 signaling pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170011

26 September 2017

Complementation between kinase-defective and activation-defective TGF-beta receptors reveals a novel form of receptor cooperativity essential for signaling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170011

26 September 2017

The p21(RAS) farnesyltransferase alpha subunit in TGF-beta and activin signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170011

26 September 2017

Caenorhabditis elegans genes sma-2, sma-3, and sma-4 define a conserved family of transforming growth factor beta pathway components

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170011

26 September 2017

Interaction of the transforming growth factor-beta type I receptor with farnesyl-protein transferase-alpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170011

26 September 2017

Type I receptors specify growth-inhibitory and transcriptional responses to transforming growth factor beta and activin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170011

26 September 2017

A mammalian protein targeted by G1-arresting rapamycin-receptor complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170011

26 September 2017

Reconstitution and transphosphorylation of TGF-beta receptor complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170011

26 September 2017

Biochemical evidence for the autophosphorylation and transphosphorylation of transforming growth factor beta receptor kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170011

26 September 2017

Human type II receptor for bone morphogenic proteins (BMPs): extension of the two-kinase receptor model to the BMPs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170011

26 September 2017

GS domain mutations that constitutively activate T beta R-I, the downstream signaling component in the TGF-beta receptor complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170011

26 September 2017

Genetic characterization and cloning of mothers against dpp, a gene required for decapentaplegic function in Drosophila melanogaster

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170011

26 September 2017

The transforming growth factor beta receptors types I, II, and III form hetero-oligomeric complexes in the presence of ligand

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170011

26 September 2017

Cloning, structure, and expression of the mitochondrial cytochrome P-450 sterol 26-hydroxylase, a bile acid biosynthetic enzyme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170011

26 September 2017

A receptor for the immunosuppressant FK506 is a cis-trans peptidyl-prolyl isomerase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170011

26 September 2017

The transforming growth factor-beta family

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170011

26 September 2017

Chemistry and Biology of the Immunophilins and Their Immunosuppressive Ligands

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170011

26 September 2017

The cytosolic-binding protein for the immunosuppressant FK-506 is both a ubiquitous and highly conserved peptidyl-prolyl cis-trans isomerase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170011

26 September 2017

Immunophilin-sensitive protein phosphatase action in cell signaling pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170011

26 September 2017

TGF beta signals through a heteromeric protein kinase receptor complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170011

26 September 2017

Substrate specificities of the peptidyl prolyl cis-trans isomerase activities of cyclophilin and FK-506 binding protein: evidence for the existence of a family of distinct enzymes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170011

26 September 2017

Partnership between DPC4 and SMAD proteins in TGF-beta signalling pathways.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170011

26 September 2017

The GS domain of the transforming growth factor-beta type I receptor is important in signal transduction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170011

26 September 2017

Phosphorylation-dependent interaction of the cytoplasmic domains of the type I and type II transforming growth factor-beta receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170011

26 September 2017

Signaling activity of homologous and heterologous transforming growth factor-beta receptor kinase complexes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170011

26 September 2017

Transforming growth factor-beta (TGF-beta)-induced down-regulation of cyclin A expression requires a functional TGF-beta receptor complex. Characterization of chimeric and truncated type I and type II receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170011

26 September 2017

FKBP-12 recognition is dispensable for signal generation by type I transforming growth factor-beta receptors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170011

17 June 2018

Betaglycan presents ligand to the TGF beta signaling receptor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170011

17 June 2018

Concomitant loss of transforming growth factor (TGF)-beta receptor types I and II in TGF-beta-resistant cell mutants implicates both receptor types in signal transduction.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170011

17 June 2018

The immunophilin FKBP12 functions as a common inhibitor of the TGF beta family type I receptors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170011

19 August 2018

The Xenopus dorsalizing factor noggin ventralizes Drosophila embryos by preventing DPP from activating its receptor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170011

19 August 2018

Xenopus Mad proteins transduce distinct subsets of signals for the TGF beta superfamily

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170011

19 August 2018

Stabilization of calcium release channel (ryanodine receptor) function by FK506-binding protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170011

19 August 2018

Identification of receptors for type-beta transforming growth factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/9233797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Graded changes in dose of a Xenopus activin A homologue elicit stepwise transitions in embryonic cell fate

1 reference

https://pubmed.ncbi.nlm.nih.gov/9233797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

FK506 binding protein mutational analysis. Defining the surface residue contributions to stability of the calcineurin co-complex

1 reference

https://pubmed.ncbi.nlm.nih.gov/9233797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of the Interaction of FKBP12 with the Transforming Growth Factor-β Type I Receptorin Vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/9233797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1093/EMBOJ/16.13.3866

1 reference

Europe PubMed Central

PMC publication ID

26 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

26 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

26 September 2017

ResearchGate publication ID

0 references

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