www.fgks.org   »   [go: up one dir, main page]

Academia.eduAcademia.edu
paper cover icon
Strontium oxide doped quaternary glasses: effect on structure, degradation and cytocompatibility

Strontium oxide doped quaternary glasses: effect on structure, degradation and cytocompatibility

Journal of Materials Science: Materials in Medicine, 2009
Jonathan Knowles
Abstract
This preliminary study focuses on the effect of adding SrO to a Ti-containing quaternary phosphate glass system denoted by P(2)O(5)-Na(2)O-CaO-TiO(2). The following four different glass compositions were manufactured: 0.5P(2)O(5)-0.17Na(2)O-0.03TiO(2)-(0.3-x)CaO-xSrO where x = 0, 0.01, 0.03 and 0.05. Structural characterisation revealed glass transition temperatures in the range 427-437 degrees C and the presence of sodium calcium phosphate as the dominant phase in all the glasses. Degradation and ion release studies conducted over a 15-day period revealed that the Sr-containing glasses showed significantly higher degradation and ion release rates than the Sr-free glass. Cytocompatibility studies performed over a 7-day period using MG63 cells showed that the addition of 5 mol% SrO yielded glasses with cell viability nearly equivalent to that observed for quaternary TiO(2) glasses.

Jonathan Knowles hasn't uploaded this paper.

Let Jonathan know you want this paper to be uploaded.

Ask for this paper to be uploaded.