Indexation

To determine (i) the extent to which recommended lifestyle healthy behaviors are adopted and the existence of positive attitudes to health; (ii) the relative influence of socio-demographic variables on multiple healthy lifestyle behaviors and positive attitudes to health; (iii) the association between healthy lifestyle behaviors and positive attitudes to health. Two distinct healthy behavioral measures were developed: (i) healthy lifestyles based on physical activity, no cigarette smoking, no/moderate alcohol drinking, maintaining a "healthy" weight and having no sleeping problems and (ii) positive health attitudes based on having positive emotional attitudes, such as: self-perceived good health status, being calm, peaceful and happy for most of the time, not expecting health to get worse and regular health check-ups. A composite healthy lifestyle index, ranging from 0 (none of behaviors met) to 5 (all behaviors met) was calculated by summing up the individual's scores...

A large variation in prognosis is observed despite the use of clinical prognostic factors in patients with advanced non-small cell lung cancer (NSCLC). It is likely that this variation is due to the different biological properties of the tumour cells. In this work we aimed to identify gene signature that could predict survival in advanced NSCLC. Total RNA was extracted from five 5 μm-thick sections of the FFPE using the High Pure RNA Paraffin Kit (Roche). RNA amplification was performed using WT-Ovation™ FFPE RNA Amplification System V2 (NuGen). The amplified cDNA was then labelled and hybridised onto Illumina HumanRef-8 v3.0 Expression BeadChips. Microarray data analysis was subsequently performed using Genespring GX version 9.0. Out of 75 FFPE samples, only 32 had sufficient RNA quality and quantity for microarray gene expression analysis. Patients were grouped into long and short survival groups based on the time to cancer-related death. After normalization and filtration, 19,002 genes were selected for differential gene expression analysis. A total of 440 genes differed significantly between the long and short survival groups (ANOVA, p <; 0.05, with Benjamini and Hochberg False Discovery Rate multiple testing correction). Unsupervised Hierarchial Clustering with Pearson correlation and average linkage identified two broad clusters of patients corresponding to the long and short survival. Thirteen genes were selected based on the TTest, 2-fold expression changes, principal components analysis and univariate Cox regression analysis and risk scores were calculated for each patient. These gene signatures were independent predictors of survival. The model was validated with a published microarray data from 130 patients with NSCLC. Using Gene Set Analysis (GSA), we found certain biological processes including metastasis and chemotherapy resistance were up-regulated in the short survival group while TID pathway and MAPKKK cascade were enriched in th- - e long survival group. As the conclusion, there is several distinct gene expression profiles associated with survival of patients with advanced stage NSCLC. Survival outcomes in advanced NSCLC could be predicted based on a 13-gene signature.

An anomalous radio continuum component at cm-wavelengths has been observed in various sources, including dark clouds. This continuum component represents a new property of the ISM. In this work we focus on one particular dark cloud, the bright reflection nebula M 78. The main goal of this work is to invetigate cm-wave continuum emission in a prominent molecular cloud, nearby and with complementary observational data. We acquired Cosmic Background Imager (CBI) visibility data of M 78 at 31 GHz with an angular resolution of $\sim 5.8\arcmin$ and CBI2 data at an angular resolution of $\sim 4.2\arcmin$. A morphological analysis was undertaken to search for possible correlations with templates that trace different emission mechanisms. Using data from WMAP and the Rhodes/HartRAO 2326 MHz survey we constructed the spectral energy distribution (SED) of M 78 in a $45\arcmin$ circular aperture. We used results from the literature to constrain the physical conditions and the stellar content. The 5 GHz -- 31 GHz spectral index in flux density ($\alpha = 1.89\pm 0.15$) is significantly different from optically thin free-free values. We also find closer morphological agreement with IR dust tracers than with free-free sources. Dust-correlated cm-wave emission that is not due to free-free is significant at small scales ($\sim 8\arcmin$). However, a free-free background dominates at cm-wavelengths on large scales ($\sim 1$ deg). We correct for this uniform background by differencing against a set of reference fields. The differenced SED of M 78 shows excess emission at 10-70 GHz over free-free and a modified blackbody, at $3.4\sigma$. The excess is matched by the spinning dust model from Draine and Lazarian (1998).

This paper deals with the theoretical analysis of ultra refraction properties of slab photonic crystals. Strong angular dispersions induced by wavelength variations have been experimentally observed near the Γ–M and Γ–K directions around λ = 1320 nm with negative and positive signs, respectively. An interpretation of these phenomena using three-dimensional plane wave method (3D-PWM) and finite-difference time-domain (3D-FDTD) calculations is presented. Equifrequency surfaces are obtained from PWM calculations and group velocities of Bloch waves excited in the patterned medium are predicted as a function of the incident wave wavelength and wavevector orientation. FDTD calculations have been performed to evaluate the influence of the finite size of the structure and to estimate the photonic crystal coupling losses for various configurations. This theoretical approach allows identifying Bloch waves responsible for the observed properties.

Climate variability and change are expected to influence the seasonal cycle in North Pacific sub-arctic marine ecosystems. The hypothesis that timing of nesting and productivity of piscivorous seabirds [kittiwakes (Rissa tridactyla and Rissa brevirostris) and murres (Uria aalge and Uria lomvia)] at the Pribilof Islands are related to variation in ocean climate as indexed by changes in sea-ice concentrations (SICs)

Two general methods for establishing the logarithmic behavior of recursively defined sequences of real numbers are presented. One is the interlacing method, and the other one is based on calculus. Both methods are used to prove logarithmic behavior of some combinatorially relevant sequences, such as Motzkin and Schr\&quot;oder numbers, sequences of values of some classic orthogonal polynomials, and many others. The calculus method extends also to two- (or more-) indexed sequences.

The epitaxial growth and the structure of Cu on Si(111)7 × 7 deposited at high temperature (&lt; 300–600°C) was investigated mainly by medium energy ion scattering (MEIS) and scanning tunneling microscopy (STM). The domain images whose periodicity is about 5.5 ± 0.2 times of the Si bulk unit were observed at high sample bias (VS = 2.5 V). The periodicity

At the conclusion of a noise annoyance survey in air-conditioned offices a new parameter was proposed. The aim was to define a noise index well correlated with subjective ratings of noise annoyance and able to account for the imbalance of the noise spectrum. As the RC Mark II procedure for rating the noise of HVAC systems in buildings introduced the “quality assessment index”(QAI), which provides a measure of the spectral imbalance of a noise, the combination of this parameter with the RC criterion number (which only measures noise ...

Air quality indices currently in use have been criticized because they do not capture additive effects of multiple pollutants, or reflect the apparent no-threshold concentration-response relationship between air pollution and health. We propose a new air quality health index (AQHI), constructed as the sum of excess mortality risk associated with individual pollutants from a time-series analysis of air pollution and

Monitoring the performance of a network by which a real-time distributed system is connected is very important. If the system is adaptive or dynamic, the resource manager can use this information to create or use new processes. We may be interested to determine how much load a ...

With increasingly higher numbers of non-English language web searchers the problems of efficient handling of non-English Web documents and user queries are becoming major issues for search engines. The main aim of this review paper is to make researchers aware of the existing problems in monolingual non-English Web retrieval by providing an overview of open issues. A significant number of

To determine whether patterns of sleeping metabolic rate (SMR) are altered in obesity. Specifically to determine the relationship between changes in SMR and body weight, body mass index (BMI, kg/m(2)), and fat-free mass (FFM); and to compare resting metabolic rate (RMR) with SMR during different periods of sleep. Eighteen healthy, pre-menopausal, obese (BMI &gt;30, n=9) and non-obese (BMI &lt;30, n=9), female subjects (six Caucasians and 12 African-Americans), with an average age of 36 y (range 22-45). Total energy expenditure (TEE or 24 h EE), metabolic rate (MR), SMR (minimum, average and maximum) and resting metabolic rate (RMR) or resting energy expenditure (REE) measured by human respiratory chamber, and external mechanical work measured by a force platform within the respiratory chamber. Physical activity index (PAL) was derived as TEE/REE. Body composition was determined by dual-energy X-ray absorptiometry (DXA). SMR decreased continuously during sleep and reached its lowest ...