Entrepreneurship is an acknowledged driver of economic growth and job creation. And job creation is a hot topic that is currently in the minds of politicians, economists, regional development officials, the media, and, of course, the general public. Formal programs and strategies designed to stimulate job growth are a constant source of intense debate. But very little discussion has been offered regarding what specific types of jobs do we want to create. In a perfect world, we want to create high-paying jobs that have long-term sustainability and are in companies that people want to work. Research from this dissertation indicates that these “highly desirable” jobs reside mainly inside technology firms. So clearly a strategy for economic growth and job creation must include a focus on increasing the number of technology firms, their initiations, and their funding sources. Historically, technology firms have been funded by wealthy families and now more recently by professional venture capitalists within the private equity industry. How-ever, the performance of venture investors in technology start-ups has been a sore point in the entrepreneurial community for many years. Whether you take the perspective that the “home-run” success rate versus just survival) is 1 out of 10 or that the failure rate is nearly 60 percent, clearly there is room for improvement. And the recent trend in U.S. venture-capital returns has not been very positive of late. According to a recent Wall Street Journal article, the average return for venture capital funds fell to 14 percent for the ten years ended June 30, 2009, down from 34 percent for the ten years ended June 30, 2008, largely because the venture returns generated in the first half of 1999 dropped out of the calculation, according to research firm Cambridge Associates LLC. While this substantial drop in performance is directly linked to the state of the public markets and the dearth of initial public offerings, there is now an ongoing debate that the fundamental business model used by venture funds may be structurally broken. As a result, venture capitalists are resorting to investing in later-stage companies and dabbling in other investment opportunities, leaving a tremendous gap in seed- and early-stage funding, which is at the birthing of technology start-ups. This does not bode well for increasing the number of technology firms into the foreseeable future. Given this depressing backdrop, no one remedy can provide a complete solution that addresses both the input side of finding more and better investable deals and the output side of more high-return exits. However, this dissertation will show that if venture funds would go back to working on improving the basic “blocking and tackling” of finding more and better inputs into the venture investment process, improvements in investment returns would be a natural follow-on. This result re-confirms earlier research that showed that, by implementing a consistent, actuarially-based methodology, venture investors will over the long-run make better investment decisions and hence higher returns, which in turn should create more lucrative exit opportunities. So one of the keys to improving venture fund returns is to make better investment decisions during the venture investment process. By applying Bayesian methods into the venture investment process, this dissertation has developed a new and novel methodology to help the venture investment decision move beyond the current ambiguous and non-repeatable processes based on gut hunches and emotions. This methodology still utilizes subjective information, but within a statistical framework that can easily map into a venture investors current decision-making processes. Furthermore, this dissertation extends previous research and shows that if a venture fund can reduce its rate of “false positive” investments i.e., investing in bad deals), that a decrease in the false positive error rate, of say 50 percent, can produce a material improvement in investment prediction accuracy of 75 percent. If we assume that capital invested in “BAD” companies firms that do not even return the original capital invested) are re-allocated to “GREAT” companies firms that return 20 times the original capital invested), this can lead to an IRR increase of 38.27 percent and improvement in Cash Return of 46.55 percent over five years, assuming a model portfolio). Given that that average venture fund size is now over 100 million dollars, the additional returns can be substantial. Operationally this means that a venture fund must start tracking and monitoring its investment statistics, much like a batting average, over time and when making investment selections, it should adopt a new paradigm of removing from the bottom instead of selecting from the top to make its final investment selections. So the significance and uniqueness of this dissertation are as follows: A) Establish the basis for the importance of technology entrepreneurship. i) Demonstrate that technology firms outperform non-technology firms in growth rates. ii) Uniqueness and Significance: Numerous research on economic impact of entrepreneurship, but no research comparing the economic impact research comparing the economic impact of technology versus non-technology entrepreneurship.; Results could impact national policy regulating the venture capital industry. B) Develop a new methodology to help venture capitalists improve their success rate of investments in technology entrepreneurship based on Bayesian methods. i) Uniqueness and Significance: Since 1946, venture investment methodologies have been generally subjective and ad hoc so very few research on analytical methodologies Zacharakis and Meyer, 2000).; Bayesian methodology applied to many areas of study, but not to venture finance.; If the success rate can be improved, this would lead to a dramatic impact on the economy. In summary, if venture funds can improve on their investment returns, then they will be more apt to invest more money in more seed and early-stage companies, resulting in more venture initiation of technology start-ups, which will then result in faster economic growth and more high-paying longer term jobs in companies that people want to work. This is the ultimate contribution of this dissertation.