Addison's disease: Difference between revisions
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'''Addison's disease''' is a rare and chronic [[endocrine system|endocrine]] disorder, named after its discoverer [[Thomas Addison]]. |
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{{Infobox medical condition (new) |
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| name = Addison's disease |
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| image = Addison'sLegs.jpg |
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| alt = |
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| caption = [[Hyperpigmentation|Darkening of the skin]] seen on the legs of an otherwise fair-skinned patient |
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| field = [[Endocrinology]] |
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| synonyms = Addison disease, primary adrenal insufficiency,<ref name=NIH2014/> primary adrenocortical insufficiency, chronic adrenal insufficiency, chronic adrenocortical insufficiency, primary hypocorticalism, primary hypocortisolism, primary hypoadrenocorticism, primary hypocorticism, primary hypoadrenalism |
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| symptoms = Abdominal pain, weakness, weight loss, [[Hyperpigmentation|darkening of the skin]]<ref name=NIH2014/> |
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| complications = [[Adrenal crisis]]<ref name=NIH2014/> |
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| females<ref name=NIH2014/> |
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| duration = |
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| causes = Problems with the [[adrenal gland]]<ref name=NIH2014/> |
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| risks = |
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| diagnosis = [[Blood test]]s, [[urine test]]s, [[medical imaging]]<ref name=NIH2014/> |
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| differential = |
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| prevention = |
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| treatment = Synthetic [[corticosteroid]] such as [[Cortisol|hydrocortisone]] and [[fludrocortisone]]<ref name=NIH2014/><ref name=Nap2014/> |
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| medication = |
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| prognosis = |
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| frequency = 0.9–1.4 per 10,000 people (developed world)<ref name=NIH2014/><ref name=Bran2014/> |
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| deaths = Doubles risk of death |
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| named after = [[Thomas Addison]] |
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}} |
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| ⚫ | Addision's disease is when the body does not produce enough of the [[hormone]] called [[cortisol]].<ref name="mednet">{{cite web |url= http://www.medicinenet.com/addison_disease/article.htm |title=Addison's Disease Causes, Symptoms, Diagnosis, and Treatment |work=medicinenet.com |year=2012 |access-date=26 October 2012}}</ref> This hormone helps the body deal with stress. It helps with maintaining [[blood pressure]] and controlling the heart's functions. It slows the rate of [[inflammation]] caused by the body's [[immune system]]. It helps with controlling the way [[insulin]] is used, and the chemical reactions of [[protein]]s, [[carbohydrate]]s and fats in the body. |
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[[File:Addison-disease.jpg|thumb|Dark patches of skin caused by Addison's disease]] |
[[File:Addison-disease.jpg|thumb|Dark patches of skin caused by Addison's disease]] |
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U.S. President [[John F. Kennedy]] is probably one of the most famous sufferers though his condition was kept secret during his presidency. |
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People with the disease suffer from weight loss, fatigue, weakness and low blood pressure.<ref name="mednet" /> Some people also get darkened patches of skin.<ref name="mednet" /> Addison's disease is treated by taking an artificial cortisol tablet.<ref>{{cite web |url=http://www.medicinenet.com/addison_disease/page7.htm#how_is_addisons_disease_treated |title=Addison's Disease Symptoms, Causes, Treatment - How is Addison's disease treated? |work=medicinenet.com |year=2012 |access-date=26 October 2012 |archive-date=29 October 2012 |archive-url=https://web.archive.org/web/20121029194723/http://www.medicinenet.com/addison_disease/page7.htm#how_is_addisons_disease_treated |url-status=dead }}</ref> |
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==References== |
==References== |
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Revision as of 19:07, 28 May 2024
Addison's disease is a rare and chronic endocrine disorder, named after its discoverer Thomas Addison.
| Addison's disease | |
|---|---|
| Other names | Addison disease, primary adrenal insufficiency,[1] primary adrenocortical insufficiency, chronic adrenal insufficiency, chronic adrenocortical insufficiency, primary hypocorticalism, primary hypocortisolism, primary hypoadrenocorticism, primary hypocorticism, primary hypoadrenalism |
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| Darkening of the skin seen on the legs of an otherwise fair-skinned patient | |
| Medical specialty | Endocrinology |
| Symptoms | Abdominal pain, weakness, weight loss, darkening of the skin[1] |
| Complications | Adrenal crisis[1] |
| Usual onset | Middle-aged females[1] |
| Causes | Problems with the adrenal gland[1] |
| Diagnostic method | Blood tests, urine tests, medical imaging[1] |
| Treatment | Synthetic corticosteroid such as hydrocortisone and fludrocortisone[1][2] |
| Frequency | 0.9–1.4 per 10,000 people (developed world)[1][3] |
| Deaths | Doubles risk of death |
Addision's disease is when the body does not produce enough of the hormone called cortisol.[4] This hormone helps the body deal with stress. It helps with maintaining blood pressure and controlling the heart's functions. It slows the rate of inflammation caused by the body's immune system. It helps with controlling the way insulin is used, and the chemical reactions of proteins, carbohydrates and fats in the body.
U.S. President John F. Kennedy is probably one of the most famous sufferers though his condition was kept secret during his presidency.
People with the disease suffer from weight loss, fatigue, weakness and low blood pressure.[4] Some people also get darkened patches of skin.[4] Addison's disease is treated by taking an artificial cortisol tablet.[5]
References
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 Cite error: The named reference
NIH2014was used but no text was provided for refs named (see the help page). - ↑ Cite error: The named reference
Nap2014was used but no text was provided for refs named (see the help page). - ↑ Cite error: The named reference
Bran2014was used but no text was provided for refs named (see the help page). - ↑ 4.0 4.1 4.2 "Addison's Disease Causes, Symptoms, Diagnosis, and Treatment". medicinenet.com. 2012. Retrieved 26 October 2012.
- ↑ "Addison's Disease Symptoms, Causes, Treatment - How is Addison's disease treated?". medicinenet.com. 2012. Archived from the original on 29 October 2012. Retrieved 26 October 2012.
