Manufacturing economics of plant‐made biologics: case studies in therapeutic and industrial enzymes
D Tusé, T Tu, KA McDonald - BioMed research international, 2014 - Wiley Online Library
Production of recombinant biologics in plants has received considerable attention as an
alternative platform to traditional microbial and animal cell culture. Industrially relevant …
alternative platform to traditional microbial and animal cell culture. Industrially relevant …
A simplified techno‐economic model for the molecular pharming of antibodies
P Mir‐Artigues, RM Twyman, D Alvarez… - Biotechnology and …, 2019 - Wiley Online Library
By the end of 2017, the Food and Drug Administration had approved a total of 77 therapeutic
monoclonal antibodies (mAbs), most of which are still manufactured today. Furthermore …
monoclonal antibodies (mAbs), most of which are still manufactured today. Furthermore …
Technoeconomic analysis of semicontinuous bioreactor production of biopharmaceuticals in transgenic rice cell suspension cultures
Biopharmaceutical protein production using transgenic plant cell bioreactor processes offers
advantages over microbial and mammalian cell culture platforms in its ability to produce …
advantages over microbial and mammalian cell culture platforms in its ability to produce …
Economic comparison between conventional and disposables‐based technology for the production of biopharmaceuticals
JL Novais, NJ Titchener‐Hooker… - Biotechnology and …, 2001 - Wiley Online Library
Time to market, cost effectiveness, and flexibility are key issues in today's biopharmaceutical
market. Bioprocessing plants based on fully disposable, presterilized, and prevalidated …
market. Bioprocessing plants based on fully disposable, presterilized, and prevalidated …
Recombinant proteins for industrial versus pharmaceutical purposes: a review of process and pricing
J Puetz, FM Wurm - Processes, 2019 - mdpi.com
Recombinant proteins have been produced for over 30 years. Applications range from
enzymes used in laundry detergents to antigen-detecting antibodies in cancer therapy …
enzymes used in laundry detergents to antigen-detecting antibodies in cancer therapy …
Techno-economic analysis of the industrial production of a low-cost enzyme using E. coli: the case of recombinant β-glucosidase
Background The enzymatic conversion of lignocellulosic biomass into fermentable sugars is
a promising approach for producing renewable fuels and chemicals. However, the cost and …
a promising approach for producing renewable fuels and chemicals. However, the cost and …
Guidelines and cost analysis for catalyst production in biocatalytic processes
P Tufvesson, J Lima-Ramos, M Nordblad… - … Process Research & …, 2011 - ACS Publications
Biocatalysis is an emerging area of technology, and to date few reports have documented
the economics of such processes. As it is a relatively new technology, many processes do …
the economics of such processes. As it is a relatively new technology, many processes do …
[PDF][PDF] Biopharmaceutical Manufacturing: Historical and Future Trends in Titers, Yields, and Efficiency in Commercial-Scale Bioprocessing.
RA Rader, ES Langer - BioProcessing Journal, 2014 - biopharma.com
This article documents the progress, cur-rent state, and projected future trends in titer and
yield as industrial and technological benchmarks for commercial-scale biopharmaceutical …
yield as industrial and technological benchmarks for commercial-scale biopharmaceutical …
Cost-effective production of biocatalysts using inexpensive plant biomass: a review
D Sakhuja, H Ghai, RK Rathour, P Kumar, AK Bhatt… - 3 Biotech, 2021 - Springer
Enzymes are the complex protein moieties, catalyze the rate of chemical reactions by
transforming various substrates to specific products and play an integral part in multiple …
transforming various substrates to specific products and play an integral part in multiple …
[BOOK][B] Biopharmaceutical processing: development, design, and implementation of manufacturing processes
G Jagschies, E Lindskog, K Lacki, PM Galliher - 2018 - books.google.com
Biopharmaceutical Processing: Development, Design, and Implementation of Manufacturing
Processes covers bioprocessing from cell line development to bulk drug substances. The …
Processes covers bioprocessing from cell line development to bulk drug substances. The …