Mucosal immunization using recombinant plant-based oral vaccines

SJ Streatfield - Methods, 2006 - Elsevier
The induction of mucosal immunity is very important in conferring protection against
pathogens that typically invade via mucosal surfaces. Delivery of a vaccine to a mucosal …

Expression systems and developments in plant‐made vaccines

MM Rigano, AM Walmsley - Immunology and cell biology, 2005 - Wiley Online Library
Delivery of vaccines to mucosal surfaces can elicit humoral and cell‐mediated responses of
the mucosal and systemic immune systems, evoke less pain and discomfort than parenteral …

Foods as production and delivery vehicles for human vaccines

SS Korban, SF Krasnyanski… - Journal of the American …, 2002 - Taylor & Francis
Vaccination is a great asset for eradication of infectious diseases in humans and animals.
With the prevalence of antibiotic resistant bacterial strains and an alarming increase in new …

Targeting and expression of antigenic proteins in transgenic plants for production of edible oral vaccines

SS Korban - In Vitro Cellular & Developmental Biology-Plant, 2002 - Springer
Exploiting plants as biological bioreactors for production and delivery of edible oral subunit
vaccines is a promising application of biotechnology. Efforts to enhance expression levels of …

Plants for delivery of edible vaccines

AM Walmsley, CJ Arntzen - Current opinion in biotechnology, 2000 - Elsevier
Over the past decade, scientific advances in molecular biology and immunology have
improved understanding of many diseases and led to the development of novel strategies …

Edible plant vaccines: applications for prophylactic and therapeutic molecular medicine

HS Mason, H Warzecha, T Mor, CJ Arntzen - Trends in molecular medicine, 2002 - cell.com
The use of edible plants for the production and delivery of vaccine proteins could provide an
economical alternative to fermentation systems. Genes encoding bacterial and viral antigens …

Plant‐made oral vaccines against human infectious diseases—are we there yet?

HT Chan, H Daniell - Plant biotechnology journal, 2015 - Wiley Online Library
Although the plant‐made vaccine field started three decades ago with the promise of
developing low‐cost vaccines to prevent infectious disease outbreaks and epidemics …

[HTML][HTML] A review of oral vaccination with transgenic vegetables

CO Tacket, HS Mason - Microbes and infection, 1999 - Elsevier
Mucosal immunization of the gastrointestinal tract is an effective way to stimulate local and
systemic immune responses. Oral vaccines must be formulated in such a way that antigens …

Targeting of plant-derived vaccine antigens to immunoresponsive mucosal sites

MM Rigano, F Sala, CJ Arntzen, AM Walmsley - Vaccine, 2003 - Elsevier
Most pathogenic microorganisms enter their host via the mucosal surfaces lining the
digestive, respiratory and urino-reproductive tracts of the body. The most efficient means of …

Development of oral vaccines for human use.

AR Fooks - Current opinion in molecular therapeutics, 2000 - europepmc.org
In developed and developing countries, oral vaccine formulations that elicit protection at
mucosal surfaces are attractive vaccine candidates. Research has shown that vaccine …