Unethical trials of interventions to reduce perinatal transmission of the Human Immunodeficiency Virus in developing countries
P Lurie, SM Wolfe - bioethics, an anthology. Kuhse HE, Singer P …, 2006 - taylorfrancis.com
P Lurie, SM Wolfe
bioethics, an anthology. Kuhse HE, Singer P. eds. Oxford: Blackwell …, 2006•taylorfrancis.comI t has been almost three years since the Journal 1 published the results of AIDS Clinical
Trials Group (ACTG) Study 076, the fi rst randomized, controlled trial in which an intervention
was proved to reduce the incidence of human immunodefi ciency virus (HIV) infection. The
antiretroviral drug zidovudine, administered orally to HIV-positive pregnant women in the
United States and France, administered intravenously during labor, and subsequently
administered to the newborn infants, reduced the incidence of HIV infection by two thirds. 2 …
Trials Group (ACTG) Study 076, the fi rst randomized, controlled trial in which an intervention
was proved to reduce the incidence of human immunodefi ciency virus (HIV) infection. The
antiretroviral drug zidovudine, administered orally to HIV-positive pregnant women in the
United States and France, administered intravenously during labor, and subsequently
administered to the newborn infants, reduced the incidence of HIV infection by two thirds. 2 …
I t has been almost three years since the Journal 1 published the results of AIDS Clinical Trials Group (ACTG) Study 076, the fi rst randomized, controlled trial in which an intervention was proved to reduce the incidence of human immunodefi ciency virus (HIV) infection. The antiretroviral drug zidovudine, administered orally to HIV-positive pregnant women in the United States and France, administered intravenously during labor, and subsequently administered to the newborn infants, reduced the incidence of HIV infection by two thirds. 2 The regimen can save the life of one of every seven infants born to HIV-infected women.
taylorfrancis.com