Proposed revisions to the Declaration of Helsinki—will they weaken the ethical principles underlying human research?
TA Brennan - New England Journal of Medicine, 1999 - Mass Medical Soc
New England Journal of Medicine, 1999•Mass Medical Soc
At a recent meeting of the human subjects committee of which I am a member, we discussed
a proposed protocol involving an analysis of human immunodeficiency virus (HIV) infection
in pregnant women and subsequent follow-up of their offspring in rural areas of a country in
sub-Saharan Africa. Recalling the recent controversy over the use of placebo in trials of
zidovudine treatment to halt perinatal transmission of HIV infection in Third World countries1–
4 and the decision by US agencies to stop funding such trials, 5 some members of our …
a proposed protocol involving an analysis of human immunodeficiency virus (HIV) infection
in pregnant women and subsequent follow-up of their offspring in rural areas of a country in
sub-Saharan Africa. Recalling the recent controversy over the use of placebo in trials of
zidovudine treatment to halt perinatal transmission of HIV infection in Third World countries1–
4 and the decision by US agencies to stop funding such trials, 5 some members of our …
At a recent meeting of the human subjects committee of which I am a member, we discussed a proposed protocol involving an analysis of human immunodeficiency virus (HIV) infection in pregnant women and subsequent follow-up of their offspring in rural areas of a country in sub-Saharan Africa. Recalling the recent controversy over the use of placebo in trials of zidovudine treatment to halt perinatal transmission of HIV infection in Third World countries1–4 and the decision by U.S. agencies to stop funding such trials,5 some members of our committee thought that the proposed protocol was ethically suspect because it did . . .