[PDF][PDF] Overexpression of circulating miRNA-21 and miRNA-146a in plasma samples of breast cancer patients

S Kumar, R Keerthana, A Pazhanimuthu, P Perumal - 2013 - nopr.niscpr.res.in
Breast cancer is the second most common malignant disease affecting Indian women and is
the leading cause of cancer-related mortality. MicroRNAs (miRNAs) are remarkably stable in
blood, which makes them novel and promising biomarkers for cancer detection and
diagnosis. In this study, we investigated whether expression levels of circulating specific
miRNAs, such as microRNA-21 (miR-21) and microRNA-146a (miR-146a) could be used as
potential biomarkers in plasma of breast cancer patients and healthy individuals. We …