Biogenesis of Fe-S cluster by the bacterial Suf system: SufS and SufE form a new type of cysteine desulfurase
L Loiseau, S Ollagnier-de-Choudens, L Nachin… - Journal of Biological …, 2003 - ASBMB
Biosynthesis of iron-sulfur clusters (Fe-S) depends on multiprotein systems. Recently, we
described the SUF system of Escherichia coli and Erwinia chrysanthemi as being important
for Fe-S biogenesis under stressful conditions. The SUF system is made of six proteins: SufC
is an atypical cytoplasmic ABC-ATPase, which forms a complex with SufB and SufD; SufA
plays the role of a scaffold protein for assembly of iron-sulfur clusters and delivery to target
proteins; SufS is a cysteine desulfurase which mobilizes the sulfur atom from cysteine and …
described the SUF system of Escherichia coli and Erwinia chrysanthemi as being important
for Fe-S biogenesis under stressful conditions. The SUF system is made of six proteins: SufC
is an atypical cytoplasmic ABC-ATPase, which forms a complex with SufB and SufD; SufA
plays the role of a scaffold protein for assembly of iron-sulfur clusters and delivery to target
proteins; SufS is a cysteine desulfurase which mobilizes the sulfur atom from cysteine and …