Probability of obsessive and compulsive symptoms in Huntington's disease

LJ Beglinger, DR Langbehn, K Duff, L Stierman… - Biological …, 2007 - Elsevier
BACKGROUND: The purpose of this study was to examine the probability of obsessive and
compulsive (OC) symptoms across stages of Huntington's disease (HD) with both cross
sectional and longitudinal data. METHODS: We present the largest sample to date of
individuals at risk for HD (N= 3964). Obsessive and compulsive symptoms were assessed
with the Unified Huntington's Disease Rating Scale OC items. RESULTS: The probability of
meeting the threshold for obsessions and compulsions increased with greater disease …