Morphometric studies of the neuropathological changes in choreatic diseases
H Lange, G Thörner, A Hopf, KF Schröder - Journal of the neurological …, 1976 - Elsevier
The striatum, pallidum and subthalamic nucleus were studied by combined morphometric
methods in serial sections of 13 brains of normal adults and of 15 patients with choreatic
diseases. In addition the volume of the hemispheres and of the cortex were measured. All
data obtained were corrected by the shrinkage factor to represent fresh brain values. In
Huntington's chorea the pallidum was more severely affected than is commonly appreciated.
The average volume reduction was of the same degree (lateral—57%, medial—50%) as that …
methods in serial sections of 13 brains of normal adults and of 15 patients with choreatic
diseases. In addition the volume of the hemispheres and of the cortex were measured. All
data obtained were corrected by the shrinkage factor to represent fresh brain values. In
Huntington's chorea the pallidum was more severely affected than is commonly appreciated.
The average volume reduction was of the same degree (lateral—57%, medial—50%) as that …