High-performance liquid chromatographic–electrospray ionization mass spectrometric analyses for the integration of natural products with modern high-throughput …

MA Strege - Journal of Chromatography B: Biomedical Sciences …, 1999 - Elsevier
Within the pharmaceutical industry, significant resources have been applied to the
identification of new drug compound leads through the use of high-throughput screening
(HTS). To meet the demand for rapid analytical characterization of biologically active
samples identified by HTS, the technique of high-performance liquid chromatography–
electrospray ionization mass spectrometry (HPLC–ESI-MS) has been utilized, and the
application of this technique specifically for the integration of natural product sample …