Factors affecting outcome in schizophrenia and their relevance for psychopharmacological treatment

AC Altamura, WV Bobo, HY Meltzer - International clinical …, 2007 - journals.lww.com
A major focus of current treatment research in schizophrenia is the determinants of long-term
outcome, including functional outcome and general medical well being, rather than just …

Strong treatment response and high maintenance rates of clozapine in childhood-onset schizophrenia

LI Kasoff, K Ahn, P Gochman, DD Broadnax… - Journal of Child and …, 2016 - liebertpub.com
Objective: Childhood-onset schizophrenia (COS) is a rare but severe form of the disorder,
which is often treatment refractory. Short-term studies have indicated a greater differential …

A six month randomized controlled trial of long acting injectable risperidone 50 and 100 mg in treatment resistant schizophrenia

HY Meltzer, JP Lindenmayer, J Kwentus, DB Share… - Schizophrenia …, 2014 - Elsevier
It has been suggested that atypical antipsychotic drugs (A-APDs) other than clozapine may
be effective to improve positive symptoms in some patients with treatment resistant …

[HTML][HTML] A randomized-controlled trial of blonanserin and olanzapine as adjunct to antipsychotics in the treatment of patients with schizophrenia and dopamine …

T Niitsu, T Hata, M Nishimoto, Y Hosoda… - Asian journal of …, 2020 - Elsevier
Dopamine supersensitivity psychosis (DSP) is a key factor contributing to the development
of antipsychotic treatment-resistant schizophrenia. We examined the efficacy and safety of …

[BOOK][B] Clinical manual of child and adolescent psychopharmacology

M McVoy, E Stepanova, RL Findling - 2023 - books.google.com
When it comes to the use of psychotropic agents in pediatric patients, it is not merely a
question of extrapolating data from adults to children and adolescents; special consideration …

Time course of improvement with antipsychotic medication in treatment-resistant schizophrenia

T Suzuki, G Remington, T Arenovich… - The British Journal of …, 2011 - cambridge.org
BackgroundImprovements are greatest in the earlier weeks of antipsychotic treatment of
patients with non-resistant schizophrenia. AimsTo address the early time-line for …

Use of very-high-dose olanzapine in treatment-resistant schizophrenia

JM Batail, B Langrée, G Robert, S Bleher… - Schizophrenia …, 2014 - Elsevier
Schizophrenia is a chronic illness with a progressive course that can be marked by
resistance to antipsychotic treatment. This can make therapeutic support challenging for the …

The dopaminergic stabilizers (−)-OSU6162 and ACR16 reverse (+)-MK-801-induced social withdrawal in rats

JP Rung, A Carlsson, KR Markinhuhta… - Progress in Neuro …, 2005 - Elsevier
Schizophrenia is manifested by positive and negative symptoms, as well as cognitive
deficits. Most existing antipsychotic agents have poor effects on the negative symptoms of …

Negative symptoms of schizophrenia are improved by the addition of paroxetine to neuroleptics: a double-blind placebo-controlled study

MC Jockers-Scherübl, A Bauer… - International clinical …, 2005 - journals.lww.com
Despite the availability of atypical antipsychotics, the treatment of negative symptoms in
schizophrenia remains a challenge. This study was designed to confirm the positive effect …

A review and Bayesian meta-analysis of clinical efficacy and adverse effects of 4 atypical neuroleptic drugs compared with haloperidol and placebo

M Klemp, IF Tvete, T Skomedal… - Journal of clinical …, 2011 - journals.lww.com
Aims: The objective of the study was to examine the efficacy and the degree of adverse
effects connected with atypical neuroleptic drugs and haloperidol by using a previously …