Regulators of Long-Term Memory Revealed by Mushroom Body-Specific Gene Expression Profiling in Drosophila melanogaster

YF Widmer, A Bilican, R Bruggmann, SG Sprecher - Genetics, 2018 - academic.oup.com
Memory formation is achieved by genetically tightly controlled molecular pathways that
result in a change of synaptic strength and synapse organization. While for short-term …

Multiple neurons encode CrebB dependent appetitive long-term memory in the mushroom body circuit

YF Widmer, C Fritsch, MM Jungo, S Almeida, B Egger… - Elife, 2018 - elifesciences.org
Lasting changes in gene expression are critical for the formation of long-term memories
(LTMs), depending on the conserved CrebB transcriptional activator. While requirement of …

Predictive olfactory learning in Drosophila

C Zhao, YF Widmer, S Diegelmann, MA Petrovici… - Scientific reports, 2021 - nature.com
Olfactory learning and conditioning in the fruit fly is typically modelled by correlation-based
associative synaptic plasticity. It was shown that the conditioning of an odor-evoked …

Dopamine, sleep, and neuronal excitability modulate amyloid-β–mediated forgetting in Drosophila

JC Kaldun, SR Lone, AM Humbert Camps… - PLoS …, 2021 - journals.plos.org
Alzheimer disease (AD) is one of the main causes of age-related dementia and
neurodegeneration. However, the onset of the disease and the mechanisms causing …

Light preference assay to study innate and circadian regulated photobehavior in Drosophila larvae

AJF Luna, AMHJ von Essen, YF Widmer… - JoVE (Journal of …, 2013 - jove.com
Light acts as environmental signal to control animal behavior at various levels. The
Drosophila larval nervous system is used as a unique model to answer basic questions on …

Memory phase-specific genes in the Mushroom Bodies identified using CrebB-target DamID

N Sgammeglia, YF Widmer, JC Kaldun, C Fritsch… - PLoS …, 2023 - journals.plos.org
The formation of long-term memories requires changes in the transcriptional program and
de novo protein synthesis. One of the critical regulators for long-term memory (LTM) …

Mushroom body-specific profiling of gene expression identifies regulators of long-term memory in Drosophila

YF Widmer, A Bilican, R Bruggmann, SG Sprecher - bioRxiv, 2017 - biorxiv.org
Memory formation is achieved by genetically tightly controlled molecular pathways that
result in a change of synaptic strength and synapse organization. While for short-term …

[CITATION][C] Author response: Multiple neurons encode CrebB dependent appetitive long-term memory in the mushroom body circuit

YF Widmer, C Fritsch, MM Jungo, S Almeida, B Egger… - sonar.ch
Author response: Multiple neurons encode CrebB dependent appetitive long-term memory in
the mushroom body circuit SONAR logo Log in Sign up EN English Français Deutsch Italiano …

[CITATION][C] Dopamine, sleep, and neuronal excitability modulate amyloid-?-mediated forgetting in Drosophila

JC Kaldun, SR Lone, AM Humbert Camps, C Fritsch… - 2021 - Public Library of Science