Repetitive DNA sequences are abundant in a broad range of species, from bacteria to
mammals, and they cover nearly half of the human genome. Repeats have always …

What are decision trees? | Nature Biotechnology Skip to main content Thank you for visiting
nature.com. You are using a browser version with limited support for CSS. To obtain the best …

New DNA sequencing technologies can sequence up to one billion bases in a single day at
low cost, putting large-scale sequencing within the reach of many scientists. Many …

An important component of many data mining projects is finding a good classification
algorithm, a process that requires very careful thought about experimental design. If not …

The parasite Plasmodium falciparum is responsible for hundreds of millions of cases of
malaria, and kills more than one million African children annually. Here we report an …

The human reference genome represents only a small number of individuals, which limits its
usefulness for genotyping. We present a method named HISAT2 (hierarchical indexing for …

This study describes comprehensive polling of transcription start and termination sites and
analysis of previously unidentified full-length complementary DNAs derived from the mouse …

Motivation: Next-generation sequencing technologies generate very large numbers of short
reads. Even with very deep genome coverage, short read lengths cause problems in de …

Methods used to sequence the transcriptome often produce more than 200 million short
sequences. We introduce StringTie, a computational method that applies a network flow …

Anopheles gambiae is the principal vector of malaria, a disease that afflicts more than 500
million people and causes more than 1 million deaths each year. Tenfold shotgun sequence …