User profiles for "author:Rubin GM"

Gerald M. Rubin

Janelia Research Campus/HHMI
Verified email at janelia.hhmi.org
Cited by 161485

Comparative genomics of the eukaryotes

GM Rubin, MD Yandell, JR Wortman, GL Gabor, Miklos… - Science, 2000 - science.org
A comparative analysis of the genomes of Drosophila melanogaster, Caenorhabditis
elegans, and Saccharomyces cerevisiae—and the proteins they are predicted to encode …

A Whole-Genome Assembly of Drosophila

EW Myers, GG Sutton, AL Delcher, IM Dew, DP Fasulo… - Science, 2000 - science.org
We report on the quality of a whole-genome assembly of Drosophila melanogaster and the
nature of the computer algorithms that accomplished it. Three independent external data …

[HTML][HTML] The role of the genome project in determining gene function: insights from model organisms

GLG Miklos, GM Rubin - Cell, 1996 - cell.com
Large amounts of data, from DNA sequences to on-line brain atlases, are rapidly
accumulating in public databases, and there is a heightened expectation that the …

Analysis of genetic mosaics in developing and adult Drosophila tissues

T Xu, GM Rubin - Development, 1993 - journals.biologists.com
We have constructed a series of strains to facilitate the generation and analysis of clones of
genetically distinct cells in developing and adult tissues of Drosophila. Each of these strains …

Gene ontology: tool for the unification of biology

M Ashburner, CA Ball, JA Blake, D Botstein, H Butler… - Nature …, 2000 - nature.com
Genomic sequencing has made it clear that a large fraction of the genes specifying the core
biological functions are shared by all eukaryotes. Knowledge of the biological role of such …

Genetic Transformation of Drosophila with Transposable Element Vectors

GM Rubin, AC Spradling - Science, 1982 - science.org
Exogenous DNA sequences were introduced into the Drosophila germ line. A rosy
transposon (ry1), constructed by inserting a chromosomal DNA fragment containing the wild …

[PDF][PDF] A GAL4-driver line resource for Drosophila neurobiology

A Jenett, GM Rubin, TTB Ngo, D Shepherd, C Murphy… - Cell reports, 2012 - cell.com
We established a collection of 7,000 transgenic lines of Drosophila melanogaster.
Expression of GAL4 in each line is controlled by a different, defined fragment of genomic …

Transposition of Cloned P Elements into Drosophila Germ Line Chromosomes

AC Spradling, GM Rubin - Science, 1982 - science.org
Recombinant DNA carrying the 3-kilobase P transposable element was injected into
Drosophila embryos of a strain that lacked such elements. Under optimum conditions, half of …

Molecular characterization of the Drosophila trp locus: a putative integral membrane protein required for phototransduction

C Montell, GM Rubin - Neuron, 1989 - cell.com
Recent studies suggest that the fly uses the inositol lipid signaling system for visual
excitation and that the Drosophila transient receptor potential (trp) mutation disrupts this …

Expression of baculovirus P35 prevents cell death in Drosophila

BA Hay, T Wolff, GM Rubin - Development, 1994 - journals.biologists.com
The baculovirus P35 protein functions to prevent apoptotic death of infected cells. We have
expressed P35 in the developing embryo and eye of the fly Drosophila melanogaster. P35 …