▪ Abstract The nervous system of higher organisms exhibits extraordinary cellular diversity
owing to complex spatial and temporal patterning mechanisms. The role of spatial patterning …

Planarians have a long history in the fields of developmental and regenerative biology.
These animals have also sparked interest in neuroscience due to their neuroanatomy …

All multicellular organisms have requirements for tumor suppression to regulate cellular
proliferation during either embryonic development or adult life. However, different organisms …

The functions of adult stem cells and tumor suppressor genes are known to intersect.
However, when and how tumor suppressors function in the lineages produced by adult stem …

Whole‐mount in situ hybridization (WISH) is a powerful tool for visualizing gene expression
patterns in specific cell and tissue types. Each model organism presents its own unique set …

Individual neural progenitors generate different cell types in a reproducible order in the
retina,,, cerebral cortex,, and probably in the spinal cord. It is unknown how neural …

The origin of new morphological characters is a long-standing problem in evolutionary
biology. Novelties arise through changes in development, but the nature of these changes is …

Many long‐lived species of animals require the function of adult stem cells throughout their
lives. However, the transcriptomes of stem cells in invertebrates and vertebrates have not …

Temporal patterning is an important aspect of embryonic development, but the underlying
molecular mechanisms are not well understood. Drosophila neuroblasts are an excellent …

The ability to discriminate between different chemical stimuli is crucial for food detection,
spatial orientation and other adaptive behaviours in animals. In the nematode …