Coccidioidomycosis is the endemic mycosis caused by the fungal pathogens Coccidioides
immitis and C. posadasii. This review is a summary of the recent advances that have been …

Fluid penetration. Given that distribution in extracellular fluid (ECF) is important, a variety of
methods have been applied to the collection and study of data on ECF distribution. Antibiotic …

We report the generation and analysis of functional data from multiple, diverse experiments
performed on a targeted 1% of the human genome as part of the pilot phase of the ENCODE …

Significant fractions of eukaryotic genomes give rise to RNA, much of which is unannotated
and has reduced protein-coding potential. The genomic origins and the associations of …

Ertapenem, a Group 1 carbapenem, is a once-a-day parenteral β-lactam antibiotic recently
licensed in the USA and Europe. Monotherapy with ertapenem dosed as 1 g once a day has …

Because nucleosomes are widely replaced by protamine in mature human sperm, the
epigenetic contributions of sperm chromatin to embryo development have been considered …

Seventy-four acutely ill patients were treated with intravenous ciprofloxacin at dosages
ranging between 200 mg every 12 h and 400 mg every 8 h. A population pharmacokinetic …

Many aerospace, civil and mechanical systems continue to be used despite ageing and the
associated potential for damage accumulation. Therefore, the ability to monitor the structural …

As procalcitonin concentrations have been shown to be elevated in patients with septicemia
and gram-negative infections in particular, we proceeded to investigate the effect of …

Background: Patients with chronic inflammatory disease (CID) treated with
immunosuppressive medications have increased risk for severe COVID-19. Although mRNA …