The fall armyworm (FAW), Spodoptera frugiperda (JE Smith, 1797), is a serious pest of
several crops, particularly maize and other cereals. It has long been known as a pest in the …

The Polycomb gene was discovered 60 years ago as a mutation inducing a particular
homeotic phenotype. Subsequent work showed that Polycomb is a general repressor of …

Systematic annotation of gene regulatory elements is a major challenge in genome science.
Direct mapping of chromatin modification marks and transcriptional factor binding sites …

To gain insight into how genomic information is translated into cellular and developmental
programs, the Drosophila model organism Encyclopedia of DNA Elements (modENCODE) …

Insulators are DNA sequences that control the interactions among genomic regulatory
elements and act as chromatin boundaries. A thorough understanding of their location and …

Polycomb group (PcG) proteins are able to maintain the memory of silent transcriptional
states of homeotic genes throughout development. In Drosophila, they form multimeric …

Emergence of polyphagous herbivorous insects entails significant adaptation to recognize,
detoxify and digest a variety of host-plants. Despite of its biological and practical importance …

The ChIP on chip method combines chromatin immunoprecipitation (ChIP) with
hybridization on DNA microarrays (chip). The ChIP technique allows one to obtain a DNA …

While translational stop codon readthrough is often used by viral genomes, it has been
observed for only a handful of eukaryotic genes. We previously used comparative genomics …

Low-cost, high-throughput gene synthesis and precise control of protein expression are of
critical importance to synthetic biology and biotechnology,,. Here we describe the …