IN Western Europe and the United States approximately 1 in 12 women develop breast
cancer. A small proportion of breast cancer cases, in particular those arising at a young age …

We systematically generated large-scale data sets to improve genome annotation for the
nematode Caenorhabditis elegans, a key model organism. These data sets include …

To gain insight into how genomic information is translated into cellular and developmental
programs, the Drosophila model organism Encyclopedia of DNA Elements (modENCODE) …

Unlocking the secrets of the genome | Nature Skip to main content Thank you for visiting
nature.com. You are using a browser version with limited support for CSS. To obtain the best …

Huntington's disease, a neurodegenerative disorder characterized by loss of striatal
neurons, is caused by an expanded, unstable trinucleotide repeat in a novel 4p16. 3 gene …

Stem cells have the remarkable ability to give rise to both self-renewing and differentiating
daughter cells. Drosophila neural stem cells segregate cell-fate determinants from the self …

Abstract The Saccharomyces Genome Database (SGD; http://www. yeastgenome. org/)
provides high-quality curated genomic, genetic, and molecular information on the genes and …

FlyMine is a data warehouse that addresses one of the important challenges of modern
biology: how to integrate and make use of the diversity and volume of current biological …

Background A fundamental concept in biology is that heritable material, DNA, is passed from
parent to offspring, a process called vertical gene transfer. An alternative mechanism of …

Despite half a century of research, the biology of dinoflagellates remains enigmatic: they
defy many functional and genetic traits attributed to typical eukaryotic cells. Genomic …